Zobrazeno 1 - 10
of 67
pro vyhledávání: '"David, Boczkowski"'
Autor:
Austin M. Eckhoff, Michael C. Brown, Karenia Landa, Ibtehaj Naqvi, Eda K. Holl, David Boczkowski, Ashley Fletcher, Kristen E. Rhodin, Minh Huy Giang, Bruce Sullenger, Georgia M. Beasley, Peter J. Allen, Smita K. Nair
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMonocytes and monocyte-derived tumor infiltrating cells have been implicated in the immunosuppression and immune evasion associated with pancreatic adenocarcinoma (PDAC). Yet, precisely how monocytes in the periphery and tumor microenvironm
Externí odkaz:
https://doaj.org/article/1eb497b660224ba3b823ad6d334a8bd8
Autor:
Matthias Gromeier, Darell D Bigner, Smita K Nair, David Boczkowski, Michael C Brown, Karenia Landa, Sin-Ho Jung, Georgia M Beasley, Norma E Farrow, Maria Angelica Selim, Rami N Al-Rohil, Aaron D Therien, Junheng Gao, Eda K Holl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background We previously reported results from a phase 1 study testing intratumoral recombinant poliovirus, lerapolturev, in 12 melanoma patients. All 12 patients received anti-PD-1 systemic therapy before lerapolturev, and 11 of these 12 patients al
Externí odkaz:
https://doaj.org/article/04605eb95ab14089a2829c1d83ca4646
Autor:
Aaron D. Therien, Georgia M. Beasley, Kristen E. Rhodin, Norma E. Farrow, Douglas S. Tyler, David Boczkowski, Rami N. Al-Rohil, Eda K. Holl, Smita K. Nair
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionB cells are key regulators of immune responses in melanoma. We aimed to explore differences in the histologic location and activation status of B cell follicles in sentinel lymph nodes (SLN) of melanoma patients.MethodsFlow cytometry was
Externí odkaz:
https://doaj.org/article/b9f0f4ada7424c5ebc1dcb3d7d1046ae
Autor:
Duane A. Mitchell, John H. Sampson, Gary E. Archer, Kent Weinhold, Laura A. Johnson, Rebecca Liu, Janet Staats, Weihua Xie, Robert Schmittling, David Boczkowski, Gabriel De Leon, Smita K. Nair
PDF file - 72KB, Phenotype of in vitro stimulated T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f9f5b7f989c617c38821c9c3312f73
https://doi.org/10.1158/1078-0432.22454721.v1
https://doi.org/10.1158/1078-0432.22454721.v1
Autor:
Duane A. Mitchell, John H. Sampson, Gary E. Archer, Kent Weinhold, Laura A. Johnson, Rebecca Liu, Janet Staats, Weihua Xie, Robert Schmittling, David Boczkowski, Gabriel De Leon, Smita K. Nair
Purpose: Despite aggressive conventional therapy, glioblastoma (GBM) remains uniformly lethal. Immunotherapy, in which the immune system is harnessed to specifically attack malignant cells, offers a treatment option with less toxicity. The expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e621a29059fc406cabeb933c1b854b1
https://doi.org/10.1158/1078-0432.c.6522825.v1
https://doi.org/10.1158/1078-0432.c.6522825.v1
Autor:
Duane A. Mitchell, John H. Sampson, Gary E. Archer, Kent Weinhold, Laura A. Johnson, Rebecca Liu, Janet Staats, Weihua Xie, Robert Schmittling, David Boczkowski, Gabriel De Leon, Smita K. Nair
PDF file - 277KB, Phenotypic analysis of CMV pp65 RNA-pulsed DCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de9bd2ae161179104c901ae03c9ccf3
https://doi.org/10.1158/1078-0432.22454730.v1
https://doi.org/10.1158/1078-0432.22454730.v1
Autor:
Duane A. Mitchell, John H. Sampson, Gary E. Archer, Kent Weinhold, Laura A. Johnson, Rebecca Liu, Janet Staats, Weihua Xie, Robert Schmittling, David Boczkowski, Gabriel De Leon, Smita K. Nair
PDF file - 69KB, Cytokine secretion analysis of CMV pp65-specific T cells co-cultured with primary GBM tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfd7ca78b97c56366b53e2e2a2ffa63
https://doi.org/10.1158/1078-0432.22454727.v1
https://doi.org/10.1158/1078-0432.22454727.v1
Autor:
Duane A. Mitchell, John H. Sampson, Gary E. Archer, Kent Weinhold, Laura A. Johnson, Rebecca Liu, Janet Staats, Weihua Xie, Robert Schmittling, David Boczkowski, Gabriel De Leon, Smita K. Nair
PDF file - 65KB, Analysis of maturation markers in dendritic cells pulsed with RNA and cultured in maturation cytokine cocktail.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e8d40fa90b3db43f5d5eb0caaf6c74
https://doi.org/10.1158/1078-0432.22454733.v1
https://doi.org/10.1158/1078-0432.22454733.v1
Publikováno v:
Nucleic acid therapeutics. 32(6)
The success of mRNA vaccines against COVID-19 is nothing short of a medical revolution. Given its chemical lability the use of mRNA as a therapeutic has been counterintuitive and met with skepticism. The development of mRNA-based COVID-19 vaccines wa
Autor:
Karenia Landa, Bruce A. Sullenger, Eda K. Holl, Victoria Frazier, David Boczkowski, Smita K. Nair
Publikováno v:
Mol Ther
Tumor cells release nucleic acid-containing proinflammatory complexes, termed nucleic acid-containing damage-associated molecular patterns (NA DAMPs), passively upon death and actively during stress. NA DAMPs activate pattern recognition receptors on