Zobrazeno 1 - 10
of 906
pro vyhledávání: '"David, Arnold"'
Autor:
Lingchen Liu, Jia Zhang, Scott Wood, Felicity Newell, Conrad Leonard, Lambros T. Koufariotis, Katia Nones, Andrew J. Dalley, Haarika Chittoory, Farzad Bashirzadeh, Jung Hwa Son, Daniel Steinfort, Jonathan P. Williamson, Michael Bint, Carl Pahoff, Phan T. Nguyen, Scott Twaddell, David Arnold, Christopher Grainge, Peter T. Simpson, David Fielding, Nicola Waddell, John V. Pearson
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Lung cancer is a heterogeneous disease and the primary cause of cancer-related mortality worldwide. Somatic mutations, including large structural variants, are important biomarkers in lung cancer for selecting targeted therapy. Ge
Externí odkaz:
https://doaj.org/article/3e541a9800144058a28c32a39366caaa
Autor:
Christopher J. Gilbert, Charles P. Rabolli, Volha A. Golubeva, Kristina M. Sattler, Meifang Wang, Arsh Ketabforoush, W. David Arnold, Christoph Lepper, Federica Accornero
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The regulation of proteostasis is fundamental for maintenance of muscle mass and function. Activation of the TGF-β pathway drives wasting and premature aging by favoring the proteasomal degradation of structural muscle proteins. Yet, how th
Externí odkaz:
https://doaj.org/article/76a086d225274d19b9e5e63a238d8b1e
Publikováno v:
IEEE Access, Vol 12, Pp 73547-73560 (2024)
Systemic vulnerabilities in the Internet of Things (IoT) pose a challenge for establishing robust cybersecurity strategies. These challenges leave IoT devices susceptible to infection, often falling victim to far-reaching Botnets. To counter these ri
Externí odkaz:
https://doaj.org/article/5fae12d290a54de1b338f091d16a7f8c
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 28, Iss 6, Pp 100219- (2024)
Objective: Pathological, age-related loss of muscle function, commonly referred to as sarcopenia, contributes to loss of mobility, impaired independence, as well as increased risk of adverse health events. Sarcopenia has been attributed to changes in
Externí odkaz:
https://doaj.org/article/ff498c5d6ea5468a86d207bdb58ae28e
Differential impact on motor unit characteristics across severities of adult spinal muscular atrophy
Autor:
Kristina Marie Kelly, Jordan Mizell, Ladan Bigdeli, Samuel Paul, Marco Antonio Tellez, Amy Bartlett, Sarah Heintzman, Jerold Everett Reynolds, Gary Brent Sterling, Kiran Francis Rajneesh, Stephen James Kolb, Bakri Elsheikh, William David Arnold
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 12, Pp 2208-2222 (2023)
Abstract Objective To test the hypotheses that decomposition electromyography (dEMG) motor unit action potential (MUAP) amplitude and firing rate are altered in SMA; dEMG parameters are associated with strength and function; dEMG parameters are corre
Externí odkaz:
https://doaj.org/article/d1576408f74743d9a8752cf72b8f9760
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-4 (2023)
Abstract In this commentary, we discuss a recent article in Trials that raised concerns about the number of poorly performed randomised trials in the medical literature and discuss the trials literature more widely. Although we all aim for higher met
Externí odkaz:
https://doaj.org/article/4114b3e335044f34b6ebb6738fd4a354
Autor:
Gregory Owendoff, Alissa Ray, Prameela Bobbili, Leatha Clark, Cory W. Baumann, Brian C. Clark, W. David Arnold
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 2439-2445 (2023)
Externí odkaz:
https://doaj.org/article/16b70d6a689945179a4bd390b15e225f