Zobrazeno 1 - 10
of 29
pro vyhledávání: '"David, Ando"'
Autor:
Tyler W H Backman, Christina Schenk, Tijana Radivojevic, David Ando, Jahnavi Singh, Jeffrey J Czajka, Zak Costello, Jay D Keasling, Yinjie Tang, Elena Akhmatskaya, Hector Garcia Martin
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 11, p e1011111 (2023)
Metabolic fluxes, the number of metabolites traversing each biochemical reaction in a cell per unit time, are crucial for assessing and understanding cell function. 13C Metabolic Flux Analysis (13C MFA) is considered to be the gold standard for measu
Externí odkaz:
https://doaj.org/article/23460991878e4f2daf19048745ca008c
Autor:
Kosuke Iwai, Maren Wehrs, Megan Garber, Jess Sustarich, Lauren Washburn, Zachary Costello, Peter W. Kim, David Ando, William R. Gaillard, Nathan J. Hillson, Paul D. Adams, Aindrila Mukhopadhyay, Hector Garcia Martin, Anup K. Singh
Publikováno v:
Microsystems & Nanoengineering, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract We present a droplet-based microfluidic system that enables CRISPR-based gene editing and high-throughput screening on a chip. The microfluidic device contains a 10 × 10 element array, and each element contains sets of electrodes for two el
Externí odkaz:
https://doaj.org/article/ddc89d0ca66e4befb929ada5d4759c71
Autor:
Garrett W. Birkel, Amit Ghosh, Vinay S. Kumar, Daniel Weaver, David Ando, Tyler W. H. Backman, Adam P. Arkin, Jay D. Keasling, Héctor García Martín
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Modeling of microbial metabolism is a topic of growing importance in biotechnology. Mathematical modeling helps provide a mechanistic understanding for the studied process, separating the main drivers from the circumstantial ones,
Externí odkaz:
https://doaj.org/article/97efd12eba8047718e7bf3427294a120
Autor:
David Ando, Ajay Gopinathan
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169455 (2017)
Nucleocytoplasmic transport is highly selective, efficient, and is regulated by a poorly understood mechanism involving hundreds of disordered FG nucleoporin proteins (FG nups) lining the inside wall of the nuclear pore complex (NPC). Previous resear
Externí odkaz:
https://doaj.org/article/bd11995e213d4666be835114e1b3679d
Autor:
Amit Ghosh, David Ando, Jennifer Gin, Weerawat Runguphan, Charles Denby, George Wang, Edward Emmanuel Kweku Baidoo, Chris Shymansky, Jay Keasling, Hector Garcia Martin
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 4 (2016)
Efficient redirection of microbial metabolism into the abundant production of desired bioproducts remains non-trivial. Here we used flux-based modeling approaches to improve yields of fatty acids in S. cerevisiae. We combined 13C labeling data with c
Externí odkaz:
https://doaj.org/article/82291d96408b44a1b4d15141cc7cd615
Autor:
Garrett W. Birkel, Amit Ghosh, Vinay S. Kumar, Daniel Weaver, David Ando, Tyler W. H. Backman, Adam P. Arkin, Jay D. Keasling, Héctor García Martín
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-2 (2017)
Externí odkaz:
https://doaj.org/article/51aa0b07f1c347cca58e56e7344f22d8
Publikováno v:
Metabolites, Vol 8, Iss 1, p 3 (2018)
Determination of internal metabolic fluxes is crucial for fundamental and applied biology because they map how carbon and electrons flow through metabolism to enable cell function. 13 C Metabolic Flux Analysis ( 13 C MFA) and Two-Scale 13 C Metabolic
Externí odkaz:
https://doaj.org/article/09b648dfe0254dafbf1f20e9a7516c89
Autor:
Gaillard Wr, Nathan J. Hillson, Peter W. Kim, Aindrila Mukhopadhyay, Hector Garcia Martin, Maren Wehrs, Paul D. Adams, Anup K. Singh, Jess Sustarich, Garber M, Washburn L, Iwai K, David Ando, Costello Z
We present a droplet-based microfluidic system that enables CRISPR-based gene editing and high-throughput screening on chip. The microfluidic device contains a 10 x 10 element array, each element containing sets of electrodes for two electric field a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e115b7eb6a1e822985ce8a6ece1266
https://doi.org/10.1101/2021.06.10.447396
https://doi.org/10.1101/2021.06.10.447396
Autor:
Kosuke Iwai, Maren Wehrs, Megan Garber, Jess Sustarich, Lauren Washburn, Zachary Costello, Peter W. Kim, David Ando, William R. Gaillard, Nathan J. Hillson, Paul D. Adams, Aindrila Mukhopadhyay, Hector Garcia Martin, Anup K. Singh
Publikováno v:
Microsystems & nanoengineering, vol 8, iss 1
We present a droplet-based microfluidic system that enables CRISPR-based gene editing and high-throughput screening on a chip. The microfluidic device contains a 10 × 10 element array, and each element contains sets of electrodes for two electric fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40c16e035aeb727bfadb3f99319748e
https://pubmed.ncbi.nlm.nih.gov/35359611
https://pubmed.ncbi.nlm.nih.gov/35359611
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73831 (2013)
Bioinformatics of disordered proteins is especially challenging given high mutation rates for homologous proteins and that functionality may not be strongly related to sequence. Here we have performed a novel bioinformatic analysis, based on the spat
Externí odkaz:
https://doaj.org/article/64c61bb5628d4f628fa604a759801dc7