Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Davette L. Behrens"'
Autor:
Robert C. Bruckner, Andrew M. Stern, Anne Higley, Graciani Nilsa R, Sandya Mandlekar, Maria Rafalski, Melody Diamond, Ross L. Stein, Eddy W. Yue, Xiang Jiang, Pearl S. Huang, Randine Dowling, Dimeo Susan, Lisa C. Grimminger, Mingzhu Zhang, Zhihong Lai, Amy L. Musselman, Swamy Yeleswaram, Davette L. Behrens, Robert A. Copeland, Andrew P. Combs, Oliff Allen I, Wei Han, Shu-Yun Zhang, Rebecca Taub, Bruce Car, George L. Trainor, Charles F. Albright, Steve P. Seitz, Daniel Hu
Publikováno v:
Molecular Cancer Therapeutics. 4:751-760
Matrix metalloproteinase (MMP)–activated prodrugs were formed by coupling MMP-cleavable peptides to doxorubicin. The resulting conjugates were excellent in vitro substrates for MMP-2, -9, and -14. HT1080, a fibrosarcoma cell line, was used as a mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45501a8fa2fc432573f20a1fa75bdc1c
https://doi.org/10.1158/1535-7163.mct-05-0006
https://doi.org/10.1158/1535-7163.mct-05-0006
Publikováno v:
Journal of Medicinal Chemistry. 37:2232-2237
A series of nitrocoumarin and nitrochromene derivatives have been prepared and shown to inhibit the phosphatidylinositol-specific phospholipase C(PLC)(IC50 < 10 micrograms/mL) isolated from human melanoma. The inhibition of PLC by nitrocoumarin 4a wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48d3c71af7b89aa097391312eec1427
https://doi.org/10.1021/jm00040a016
https://doi.org/10.1021/jm00040a016
Publikováno v:
ChemInform. 25
A series of nitrocoumarin and nitrochromene derivatives have been prepared and shown to inhibit the phosphatidylinositol-specific phospholipase C(PLC)(IC50 < 10 micrograms/mL) isolated from human melanoma. The inhibition of PLC by nitrocoumarin 4a wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d243eb1453b826a3eec99003e10d14
https://doi.org/10.1002/chin.199448154
https://doi.org/10.1002/chin.199448154
Publikováno v:
Journal of biomolecular screening. 4(1)
Impairment of G proteincoupled seven-transmembrane (7 TM) receptor function has been implicated in a variety of different pathologic conditions, suggesting that the discovery of specific antagonists may lead to the development of successful therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40ce5823cfb4aec730c9a999e5ff3c
https://pubmed.ncbi.nlm.nih.gov/10838409
https://pubmed.ncbi.nlm.nih.gov/10838409
Autor:
Barry Allen Stone, George L. Trainor, Siew Peng Ho, Davette L. Behrens, Dustin H. O. Britton, Lynn Leffet, Jeffrey Allan Miller, Frank W. Hobbs
Publikováno v:
Nucleic acids research. 24(10)
Antisense oligonucleotides can vary significantly and unpredictably in their ability to inhibit protein synthesis. Libraries of chimeric oligonucleotides and RNase H were used to cleave and thereby locate sites on human multidrug resistance-1 RNA tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6503ef33055d01d30f40b4741a30ad3b
https://pubmed.ncbi.nlm.nih.gov/8657572
https://pubmed.ncbi.nlm.nih.gov/8657572
Autor:
Davette L. Behrens, Huey-Shin L. Shen, Charles C. Whitney, Daniel L. Dexter, Martin Forbes, Shih-Fong Chen
Publikováno v:
Cancer chemotherapy and pharmacology. 22(3)
The distribution of the novel anticancer drug candidate Brequinar Sodium (DuP 785, NSC 368390) was studied in control mice and mice implanted subcutaneously with human colon carcinoma xenografts. Mice were given radiolabeled 14C-Brequinar Sodium intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c235b7a858570c419dcfdb8d40927e3
https://pubmed.ncbi.nlm.nih.gov/3409452
https://pubmed.ncbi.nlm.nih.gov/3409452