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Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder.

Autor: Simões de Oliveira L; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK., O'Leary HE; School of Medicine, University of Colorado, Denver, CO, USA.; Department of Pharmacology, University of Colorado Denver, 12800 East 19th Ave, Aurora, CO, 80045, USA., Nawaz S; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK.; National Centre for Biological Sciences, Tata Institute for Fundamental Research, Bangalore, 560065, India.; Centre for Brain Development and Repair, Instem, Bangalore, India., Loureiro R; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK., Davenport EC; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK., Baxter P; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Louros SR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK., Dando O; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Perkins E; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK., Peltier J; Faculty of Medical Sciences, Newcastle University Biosciences Institute, Newcastle upon Tyne, NE2 4HH, UK., Trost M; Faculty of Medical Sciences, Newcastle University Biosciences Institute, Newcastle upon Tyne, NE2 4HH, UK., Osterweil EK; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK., Hardingham GE; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Cousin MA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK.; Centre for Brain Development and Repair, Instem, Bangalore, India., Chattarji S; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK.; National Centre for Biological Sciences, Tata Institute for Fundamental Research, Bangalore, 560065, India.; Centre for Brain Development and Repair, Instem, Bangalore, India., Booker SA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK., Benke TA; School of Medicine, University of Colorado, Denver, CO, USA. tim.benke@cuanschutz.edu.; Department of Pharmacology, University of Colorado Denver, 12800 East 19th Ave, Aurora, CO, 80045, USA. tim.benke@cuanschutz.edu., Wyllie DJA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. david.j.a.wyllie@ed.ac.uk.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK. david.j.a.wyllie@ed.ac.uk.; Centre for Brain Development and Repair, Instem, Bangalore, India. david.j.a.wyllie@ed.ac.uk.; Centre for Discovery Brain Sciences, Simons Initiative for the Developing Brain, University of Edinburgh, Hugh Robson Building, Edinburgh, EH8 9XD, UK. david.j.a.wyllie@ed.ac.uk., Kind PC; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. p.kind@ed.ac.uk.; Simons Initiative for the Developing Brain, Patrick Wild Centre, University of Edinburgh, Edinburgh, UK. p.kind@ed.ac.uk.; Centre for Brain Development and Repair, Instem, Bangalore, India. p.kind@ed.ac.uk.; Centre for Discovery Brain Sciences, Simons Initiative for the Developing Brain, University of Edinburgh, Hugh Robson Building, Edinburgh, EH8 9XD, UK. p.kind@ed.ac.uk.

Publikováno v: Molecular autism [Mol Autism] 2024 Jun 14; Vol. 15 (1), pp. 28. Date of Electronic Publication: 2024 Jun 14.

Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy.

Autor: Bonnycastle K; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK. Katherine.Bonnycastle@gmail.com.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK. Katherine.Bonnycastle@gmail.com.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK. Katherine.Bonnycastle@gmail.com.; Service de Génétique Médicale, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Université de Montréal, Montreal, QC, Canada. Katherine.Bonnycastle@gmail.com., Dobson KL; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK., Blumrich EM; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK., Gajbhiye A; Newcastle University Biosciences Institute, Faculty of Medical Sciences, NE2 4HH, Newcastle upon Tyne, UK., Davenport EC; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK., Pronot M; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK., Steinruecke M; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK., Trost M; Newcastle University Biosciences Institute, Faculty of Medical Sciences, NE2 4HH, Newcastle upon Tyne, UK., Gonzalez-Sulser A; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK., Cousin MA; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK. M.Cousin@ed.ac.uk.; Simons Initiative for the Developing Brain, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK. M.Cousin@ed.ac.uk.; Muir Maxwell Epilepsy Centre, Hugh Robson Building, George Square, University of Edinburgh, EH8 9XD, Edinburgh, Scotland, UK. M.Cousin@ed.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2023 Aug 30; Vol. 14 (1), pp. 5285. Date of Electronic Publication: 2023 Aug 30.