Zobrazeno 1 - 10
of 630
pro vyhledávání: '"Davenport, EE"'
Autor:
Vanderstichele T; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Burnham KL; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., de Klein N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Tardaguila M; Human Technopole, Fondazione Human Technopole, Milan, Italy., Howell B; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Walter K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Kundu K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Puddicombe Way, Cambridge, UK., Koeppel J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Lee W; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Tokolyi A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Persyn E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Nath AP; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Marten J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK; Department of Medicine, University of Melbourne, Austin Health, Melbourne, VIC, Australia., Roberts DJ; Radcliffe Department of Medicine, John Radcliffe Hospital, Oxford, UK; Clinical Services, NHS Blood and Transplant, Oxford Centre, John Radcliffe Hospital, Oxford, UK., Di Angelantonio E; Human Technopole, Fondazione Human Technopole, Milan, Italy; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Danesh J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Berton A; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Molndal, Sweden., Platt A; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Soranzo N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; Human Technopole, Fondazione Human Technopole, Milan, Italy; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Puddicombe Way, Cambridge, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK., Parts L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Inouye M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Davenport EE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: ed5@sanger.ac.uk.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2024 Aug 08; Vol. 111 (8), pp. 1524-1543. Date of Electronic Publication: 2024 Jul 24.
Autor:
Owen NE; Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, CB2 0QQ, U.K., Williams TL; Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, CB2 0QQ, U.K., Maguire JJ; Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, CB2 0QQ, U.K., Kuc RE; Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, CB2 0QQ, U.K., Davenport EE; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, U.K., Davenport AP; Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, CB2 0QQ, U.K.
Publikováno v:
Bioscience reports [Biosci Rep] 2024 Jul 31; Vol. 44 (7).
Autor:
Burnham KL; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Milind N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; University of Cambridge, Cambridge, UK., Lee W; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Kwok AJ; Centre for Human Genetics, University of Oxford, Oxford, UK., Cano-Gamez K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; Centre for Human Genetics, University of Oxford, Oxford, UK., Mi Y; Centre for Human Genetics, University of Oxford, Oxford, UK., Geoghegan CG; Centre for Human Genetics, University of Oxford, Oxford, UK., Zhang P; Centre for Human Genetics, University of Oxford, Oxford, UK; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., McKechnie S; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Soranzo N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Hinds CJ; Centre for Translational Medicine & Therapeutics, William Harvey Research Institute, Faculty of Medicine & Dentistry, Queen Mary University of London, London, UK., Knight JC; Centre for Human Genetics, University of Oxford, Oxford, UK; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK. Electronic address: julian@well.ox.ac.uk., Davenport EE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: ed5@sanger.ac.uk.
Publikováno v:
Cell genomics [Cell Genom] 2024 Jul 10; Vol. 4 (7), pp. 100587. Date of Electronic Publication: 2024 Jun 18.
Autor:
Mi Y; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Burnham KL; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge CB10 1SA, UK., Charles PD; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK., Heilig R; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK., Vendrell I; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford OX3 7BN, UK., Whalley J; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Torrance HD; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College, London SW7 2AZ, UK., Antcliffe DB; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College, London SW7 2AZ, UK.; Department of Critical Care, Imperial College Healthcare NHS Trust, London W2 1NY, UK., May SM; Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Oxford OX3 9DU, UK., Berridge G; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK., Hutton P; Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7JX, UK., Geoghegan CG; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Radhakrishnan J; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Nesvizhskii AI; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Yu F; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Davenport EE; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge CB10 1SA, UK., McKechnie S; Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7JX, UK., Davies R; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College, London SW7 2AZ, UK., O'Callaghan DJP; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College, London SW7 2AZ, UK.; Department of Critical Care, Imperial College Healthcare NHS Trust, London W2 1NY, UK., Patel P; Department of Critical Care, Imperial College Healthcare NHS Trust, London W2 1NY, UK., Del Arroyo AG; Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Oxford OX3 9DU, UK., Gordon AC; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College, London SW7 2AZ, UK.; Department of Critical Care, Imperial College Healthcare NHS Trust, London W2 1NY, UK., Ackland GL; Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK., Hinds CJ; Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK., Fischer R; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford OX3 7BN, UK., Knight JC; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford OX3 7BN, UK.; NIHR Oxford Biomedical Research Centre, Oxford OX3 9DU, UK.
Publikováno v:
Science translational medicine [Sci Transl Med] 2024 Jun 05; Vol. 16 (750), pp. eadh0185. Date of Electronic Publication: 2024 Jun 05.
Autor:
Antcliffe DB; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK d.antcliffe@imperial.ac.uk.; Centre for Perioperative and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK., Mi Y; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Santhakumaran S; Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK., Burnham KL; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Prevost AT; Nightingale-Saunders Clinical Trials and Epidemiology Unit, King's College London, London, UK., Ward JK; Conway Institute, School of Medicine, University College Dublin, Dublin, Ireland., Marshall TJ; Department of Anaesthetics, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.; Central Clinical School Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Bradley C; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK., Al-Beidh F; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK., Hutton P; Adult Intensive Care Unit, John Radcliffe Hospital, Oxford, UK., McKechnie S; Adult Intensive Care Unit, John Radcliffe Hospital, Oxford, UK., Davenport EE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Hinds CJ; William Harvey Research Institute, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., O'Kane CM; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; Regional Intensive Care Unit, Royal Victoria Hospital, Belfast, UK.; Northern Ireland Clinical Trials Unit, Royal Hospitals, Belfast, UK., Shankar-Hari M; The Queen's Medical Research Institute, The University of Edinburgh College of Medicine and Veterinary Medicine, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK., Gordon AC; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.; Centre for Perioperative and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK., Knight JC; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Publikováno v:
Thorax [Thorax] 2024 May 20; Vol. 79 (6), pp. 515-523. Date of Electronic Publication: 2024 May 20.
A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.
Autor:
Torrance HD; Division of Anaesthetics, Pain Medicine & Intensive Care Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London. UK., Zhang P; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., Longbottom ER; Centre for Translational Medicine & Therapeutics, William Harvey Institute, Faculty of Medicine & Dentistry at Queen Mary University of London, London. UK., Mi Y; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK., Whalley JP; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK.; Center for Cancer Cell Biology, Immunology, and Infection, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL., Allcock A; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK., Kwok AJ; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK., Cano-Gamez E; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK., Geoghegan CG; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK., Burnham KL; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK., Antcliffe DB; Division of Anaesthetics, Pain Medicine & Intensive Care Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London. UK., Davenport EE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK., Pearse RM; Centre for Translational Medicine & Therapeutics, William Harvey Institute, Faculty of Medicine & Dentistry at Queen Mary University of London, London. UK., O'Dwyer MJ; Department of Anaesthesia and Critical Care, St Vincent's University Hospital, Dublin. Ireland., Hinds CJ; Centre for Translational Medicine & Therapeutics, William Harvey Institute, Faculty of Medicine & Dentistry at Queen Mary University of London, London. UK., Knight JC; Wellcome Centre for Human Genetics, University of Oxford, Oxford. UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., Gordon AC; Division of Anaesthetics, Pain Medicine & Intensive Care Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London. UK.
Publikováno v:
Annals of surgery [Ann Surg] 2024 Mar 01; Vol. 279 (3), pp. 510-520. Date of Electronic Publication: 2023 Jul 27.
Autor:
Angchagun K; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Boonklang P; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Chomkatekaew C; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Pakdeerat S; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Wongsuwan G; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Amornchai P; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Wuthiekanun V; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Panapipat S; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Ngernseng T; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Waithira N; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Walton S; Wellcome Sanger Institute, Hinxton, England, CB10 1SA, UK., Limmathurotsakul D; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Surawong A; Sunpasitthiprasong Regional Hospital, Ubon Ratchathani, 34000, Thailand., Siriboon S; Sunpasitthiprasong Regional Hospital, Ubon Ratchathani, 34000, Thailand., Chamnan P; Sunpasitthiprasong Regional Hospital, Ubon Ratchathani, 34000, Thailand., Chantratita N; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand., Dunachie S; Nuffield Department of Medicine, Centre of Tropical Medicine and Global Health, University of Oxford, Oxford, England, OX3 7LG, UK., Corander J; Wellcome Sanger Institute, Hinxton, England, CB10 1SA, UK.; Institute of Basic Medical Sciences, Faculty of Medcine, University of Oslo, Oslo, Oslo, 0317, Norway., Davenport EE; Wellcome Sanger Institute, Hinxton, England, CB10 1SA, UK., Knight J; Wellcome Centre for Human Genetics, University of Oxford, Oxford, England, OX3 7BN, UK., Parkhill J; Department of Veterinary Medicine, University of Cambridge, Cambridge, England, CB3 0ES, UK., Peacock SJ; Department of Medicine, University of Cambridge, Cambridge, England, CB2 0SP, UK., Thomson NR; Wellcome Sanger Institute, Hinxton, England, CB10 1SA, UK., Day NPJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand.; Nuffield Department of Medicine, Centre of Tropical Medicine and Global Health, University of Oxford, Oxford, England, OX3 7LG, UK., Chewapreecha C; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand.; Wellcome Sanger Institute, Hinxton, England, CB10 1SA, UK.; Department of Clinical Medicine, Faculty of Tropical Medicine, Mahidol University, Salaya, Nakhon Pathom, 10400, Thailand.
Publikováno v:
Wellcome open research [Wellcome Open Res] 2023 Nov 02; Vol. 8, pp. 347. Date of Electronic Publication: 2023 Nov 02 (Print Publication: 2023).
Autor:
Cano-Gamez, E, Burnham, KL, Goh, C, Allcock, A, Malick, ZH, Overend, L, Kwok, A, Smith, DA, Peters-Sengers, H, Antcliffe, D, GAinS Investigators, McKechnie, S, Scicluna, BP, Van der Poll, T, Gordon, AC, Hinds, CJ, Davenport, EE, Knight, JC, Webster, N, Galley, H, Taylor, J, Hall, S, Addison, J, Roughton, S, Tennant, H, Guleri, A, Waddington, N, Arawwawala, D, Durcan, J, Short, A, Swan, K, Williams, S, Smolen, S, Mitchell-Inwang, C, Gordon, T, Errington, E, Templeton, M, Venatesh, P, Ward, G, McCauley, M, Baudouin, S, Higham, C, Soar, J, Grier, S, Hall, E, Brett, S, Kitson, D, Wilson, R, Mountford, L, Moreno, J, Hall, P, Hewlett, J, Garrard, C, Millo, J, Young, D, Hutton, P, Parsons, P, Smiths, A, Faras-Arraya, R, Raymode, P, Thompson, J, Bowrey, S, Kazembe, S, Rich, N, Andreou, P, Hales, D, Roberts, E, Fletcher, S, Rosbergen, M, Glister, G, Cuesta, JM, Bion, J, Millar, J, Perry, EJ, Willis, H, Mitchell, N, Ruel, S, Carrera, R, Wilde, J, Nilson, A, Lees, S, Kapila, A, Jacques, N, Atkinson, J, Brown, A, Prowse, H, Krige, A, Bland, M, Bullock, L, Harrison, D, Mills, G, Humphreys, J, Armitage, K, Laha, S, Baldwin, J, Walsh, A, Doherty, N, Drage, S, Ortiz-Ruiz de Gordoa, L, Lowes, S, Walsh, H, Calder, V, Swan, C, Payne, H, Higgins, D, Andrews, S, Mappleback, S, Hind, C, Watson, D, McLees, E, Purdy, A, Stotz, M, Ochelli-Okpue, A, Bonner, S, Whitehead, I, Hugil, K, Goodridge, V, Cawthor, L, Kuper, M, Pahary, S, Bellingan, G, Marshall, R, Montgomery, H, Ryu, JH, Bercades, G, Boluda, S, Bentley, A, Mccalman, K, Jefferies, F, Knight, J, Davenport, E, Burnham, K, Maugeri, N, Radhakrishnan, J, Mi, Y
Publikováno v:
Science translational medicine, 14(669):eabq4433. American Association for the Advancement of Science
Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing millions of global deaths each year. To alleviate this burden, improved prognostication and biomarkers of response are urgently needed. We investigated the use
Autor:
Kwok AJ; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Allcock A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Ferreira RC; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Cano-Gamez E; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Smee M; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Burnham KL; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Zurke YX; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., McKechnie S; John Radcliffe Hospital, Oxford Universities Hospitals NHS Foundation Trust, Oxford, UK., Mentzer AJ; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; John Radcliffe Hospital, Oxford Universities Hospitals NHS Foundation Trust, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Monaco C; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Udalova IA; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Hinds CJ; William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University, London, UK., Todd JA; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Davenport EE; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Knight JC; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. julian.knight@well.ox.ac.uk.; John Radcliffe Hospital, Oxford Universities Hospitals NHS Foundation Trust, Oxford, UK. julian.knight@well.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. julian.knight@well.ox.ac.uk.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK. julian.knight@well.ox.ac.uk.
Publikováno v:
Nature immunology [Nat Immunol] 2023 May; Vol. 24 (5), pp. 767-779. Date of Electronic Publication: 2023 Apr 24.
Autor:
Xu Y; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. yx322@medschl.cam.ac.uk.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. yx322@medschl.cam.ac.uk.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK. yx322@medschl.cam.ac.uk., Ritchie SC; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Liang Y; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Timmers PRHJ; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Pietzner M; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Computational Medicine, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK., Lannelongue L; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Lambert SA; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK., Tahir UA; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., May-Wilson S; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Foguet C; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Nath AP; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Persyn E; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Peters JE; Department of Immunology and Inflammation, Faculty of Medicine, Imperial College London, London, UK., Oliver-Williams C; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Deng S; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Prins B; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Bomba L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; BioMarin Pharmaceutical, Novato, CA, USA., Soranzo N; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Behaviour, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Genomics Research Centre, Human Technopole, Milan, Italy., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Behaviour, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; 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Publikováno v:
Nature [Nature] 2023 Apr; Vol. 616 (7955), pp. 123-131. Date of Electronic Publication: 2023 Mar 29.