Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daven N. Jackson-Humbles"'
Autor:
Surayma Waidyanatha, June K. Dunnick, Daven N. Jackson-Humbles, Esra Mutlu, Sam J. Harbo, David E. Malarkey, Barney Sparrow, Keith R. Shockley, Emily Cheng, Molly Vallant, Nicholas J. Machesky, B Collins, Michelle C. Cora, Veronica G. Robinson, Kristin Patton, Amy Zmarowski, Jamie S. Richey
Publikováno v:
Toxicol Lett
The relative toxicity of three legacy and six emerging brominated flame retardants* was studied in the male Harlan Sprague Dawley rat. The hepatocellular and thyroid toxicity of each flame retardant was evaluated following five-day exposure to each o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34754410a6f532435db5e30c9ca11943
https://doi.org/10.1016/j.toxlet.2020.07.016
https://doi.org/10.1016/j.toxlet.2020.07.016
Autor:
Carine Holz, Ning Li, Arthur K. Cho, Daven N. Jackson-Humbles, Damansher Sidhu, John R. Froines, James G. Wagner, Ryan P. Lewandowski, Arantzazu Eiguren-Fernandez, Peyman Akbari, Jack R. Harkema
Publikováno v:
Toxicology letters. 356
Although exposure to ambient particulate matter (PM) is linked to asthma, the health effects of co-existing vapor-phase organic pollutants (vapor) and their combined effects with PM on this disease are poorly understood. We used a murine asthma model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3211ffacc4f97c08fe26c6bbae0d3601
https://pubmed.ncbi.nlm.nih.gov/34863859
https://pubmed.ncbi.nlm.nih.gov/34863859
Autor:
Jon A. Hotchkiss, Ryan A Lewandowski, Daven N. Jackson-Humbles, Shannon M. Krieger, Amy Freeland, Elyse A Eldridge, Jack R. Harkema, James G. Wagner
Publikováno v:
Toxicologic pathology. 48(7)
Rats repeatedly exposed to high airborne concentrations of ethylene develop eosinophilic rhinitis and mucous cell hyperplasia/hypertrophy (MCH) in nasal respiratory epithelium. Mechanisms underlying these lesions are not well understood to inform occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbb2357d26564c32840779259d07d8f
https://pubmed.ncbi.nlm.nih.gov/32975493
https://pubmed.ncbi.nlm.nih.gov/32975493
Autor:
Matthew D. Stout, Matthew Buccellato, Helen Cunny, David E. Malarkey, Kristine L. Witt, Shawn F. Harris, Dawn Fallacara, Rachel P. Frawley, Irene Inok Surh, Dori R. Germolec, Wimolnut Manheng, Kimber L. White, Greg Travlos, Grace E. Kissling, Daven N. Jackson-Humbles, Keith R. Shockley, Scott S. Auerbach
Publikováno v:
Toxicology
2-Methoxy-4-nitroaniline (MNA), an intermediate in the synthesis of azo dyes used in textiles and paints, is structurally similar to carcinogenic anilines. Human exposure occurs primarily in the occupational setting through handling of dye dust, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fddb6f4ec48da69b214be941168ea2
https://pubmed.ncbi.nlm.nih.gov/32380031
https://pubmed.ncbi.nlm.nih.gov/32380031
Autor:
Daven N. Jackson-Humbles, Rance Nault, Phillip T. Brooks, Timothy R. Zacharewski, Jack R. Harkema, Chee Bing Ong, Christina Brandenberger, Kazuyoshi Kumagai, Ryan P. Lewandowski, James G. Wagner
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 54:331-340
Inhalation exposures to ozone commonly encountered in photochemical smog cause airway injury and inflammation. Elevated ambient ozone concentrations have been epidemiologically associated with nasal airway activation of neutrophils and eosinophils. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb211415d131d65f6738bf626b6dce
https://doi.org/10.1165/rcmb.2015-0165oc
https://doi.org/10.1165/rcmb.2015-0165oc
Autor:
Darlene Dixon, Barry S. McIntyre, Ronald A. Herbert, John C. Seely, Daven N. Jackson-Humbles, Paul M. D. Foster, David E. Malarkey
Publikováno v:
Toxicologic pathology. 46(4)
Congenital uterine wall cysts arising from paramesonephric (Mullerian) and mesonephric (Wolffian) ducts are typically incidental findings in most species. We used immunohistochemistry (IHC) to characterize and determine the origin of uterine cysts in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14001d80bd7125e39f87e9c0d452a1e
https://pubmed.ncbi.nlm.nih.gov/29706125
https://pubmed.ncbi.nlm.nih.gov/29706125
Autor:
Ryan P. Lewandowski, James G. Wagner, Jack R. Harkema, Steven J. Van Dyken, Nicholas Buglak, Ning Li, Daven N. Jackson-Humbles, Kaylin White, Kazuyoshi Kumagai
Publikováno v:
Toxicologic pathology. 45(6)
Exposure to elevated levels of ambient ozone in photochemical smog is associated with eosinophilic airway inflammation and nonatopic asthma in children. In the present study, we determined the role of innate lymphoid cells (ILCs) in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d794a328507376892e3cc6bf03f50c2
https://pubmed.ncbi.nlm.nih.gov/28891433
https://pubmed.ncbi.nlm.nih.gov/28891433
Autor:
Daven N. Jackson-Humbles, Jack R. Harkema, Nicholas A. Vetter, Ryan P. Lewandowski, Lucas A. Hotchkiss, James G. Wagner
Publikováno v:
Toxicologic pathology. 45(1)
Ozone is an irritating gas found in photochemical smog. Epidemiological associations have been made between the onset of asthma and childhood exposures to increasing levels of ambient ozone (i.e., air pollutant–induced nonatopic asthma). Individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae15ea44c41b88e2c2235c72504e19d7
https://pubmed.ncbi.nlm.nih.gov/28068894
https://pubmed.ncbi.nlm.nih.gov/28068894
Autor:
Cheryl E. Rockwell, Christina Brandenberger, Ning Li, Jack R. Harkema, Daven N. Jackson-Humbles, James G. Wagner
Publikováno v:
Clinical & Experimental Allergy. 44:1282-1292
SummaryBackground The prevalence of asthma in the elderly is increasing and associated with higher mortality than in children or young adults. However, the effects of age on the development and character of allergic asthma have been understudied. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095c638aaa7ddfdee976bdca09a0bd27
https://doi.org/10.1111/cea.12388
https://doi.org/10.1111/cea.12388
Autor:
Jack R. Harkema, Krista K. Greenwood, Steven P. Proper, James G. Wagner, Daven N. Jackson-Humbles, Yogesh Saini, Lori A. Bramble, John J. LaPres
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 302:L455-L462
Allergic airway disease is characterized by a T helper type 2 cell-mediated airway inflammation and airway hyperresponsiveness. Little is known about the role of hypoxia-mediated signaling in the progression of the disease. To address this knowledge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb35ea3faa7f38192ba131ff573bb37d
https://doi.org/10.1152/ajplung.00193.2011
https://doi.org/10.1152/ajplung.00193.2011