Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Dave Tang"'
Autor:
Timo Lassmann, Richard W. Francis, Alexia Weeks, Dave Tang, Sarra E. Jamieson, Stephanie Broley, Hugh J. S. Dawkins, Lauren Dreyer, Jack Goldblatt, Tudor Groza, Benjamin Kamien, Cathy Kiraly-Borri, Fiona McKenzie, Lesley Murphy, Nicholas Pachter, Gargi Pathak, Cathryn Poulton, Amanda Samanek, Rachel Skoss, Jennie Slee, Sharron Townshend, Michelle Ward, Gareth S. Baynam, Jenefer M. Blackwell
Publikováno v:
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract Exome sequencing has enabled molecular diagnoses for rare disease patients but often with initial diagnostic rates of ~25−30%. Here we develop a robust computational pipeline to rank variants for reassessment of unsolved rare disease patie
Externí odkaz:
https://doaj.org/article/811cb355cf5b4897b431fd467c9f3752
Autor:
James W Kijas, David Townley, Brian P Dalrymple, Michael P Heaton, Jillian F Maddox, Annette McGrath, Peter Wilson, Roxann G Ingersoll, Russell McCulloch, Sean McWilliam, Dave Tang, John McEwan, Noelle Cockett, V Hutton Oddy, Frank W Nicholas, Herman Raadsma, International Sheep Genomics Consortium
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4668 (2009)
The genetic structure of sheep reflects their domestication and subsequent formation into discrete breeds. Understanding genetic structure is essential for achieving genetic improvement through genome-wide association studies, genomic selection and t
Externí odkaz:
https://doaj.org/article/fca2207878ca4bbb8449ca5e3a3576ce
Autor:
Sarra E. Jamieson, Richard W. Francis, Timo Lassmann, Elizabeth S. H. Scaman, Jenefer M. Blackwell, Heather J. Cordell, Dave Tang, Genevieve Syn, Harvey Coates, Michaela Fakiola, Denise Anderson
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Our goal was to identify genetic risk factors for severe otitis media (OM) in Aboriginal Australians. Methods Illumina® Omni2.5 BeadChip and imputed data were compared between 21 children with severe OM (multiple episodes chronic suppurat
Autor:
Marina Oliva, Tim Stuart, Dave Tang, Jahnvi Pflueger, Daniel Poppe, Jafar S. Jabbari, Scott Gigante, Jonathan Michael Dragwidge, James Whelan, Mathew G. Lewsey, Ryan Lister
Roots are fundamental organs for plant development and response to their environment: they anchor the plant to its growth substrate, uptake nutrients and water vital to plant growth, and can sense and respond to a variety of biotic and abiotic stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68601860538236eade157b3a388a3ddd
https://doi.org/10.1101/2022.03.04.483008
https://doi.org/10.1101/2022.03.04.483008
Autor:
Kazushi Hiranuka, Keigo Takahashi, Dave Tang, Noriko Watanabe, Takashi Yamada, Yuji Mishima, Norihiro Fujinami, Manami Shimomura, Toshihiro Suzuki, Tetsuya Nakatsura, Norihiro Nakamura
Publikováno v:
Cancer Research. 82:6389-6389
Background: Personalized neoantigen-based therapies are being actively developed with several clinical trials currently ongoing. The standard methodology to identify patient specific neoantigens relies on computational algorithms for analyzing mutati
Autor:
Jenefer M. Blackwell, Gargi Pathak, Hugh Dawkins, Cathryn Poulton, Lauren Dreyer, Alexia L. Weeks, Fiona Haslam McKenzie, Amanda Samanek, Jack Goldblatt, Richard W. Francis, Nicholas Pachter, Gareth Baynam, Lesley Murphy, Michelle Ward, Timo Lassmann, Tudor Groza, Cathy Kiraly-Borri, Benjamin Kamien, Jennie Slee, Stephanie Broley, Dave Tang, Sharron Townshend, Sarra E. Jamieson, Rachel Skoss
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-11 (2020)
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-11 (2020)
Exome sequencing has enabled molecular diagnoses for rare disease patients but often with initial diagnostic rates of ~25−30%. Here we develop a robust computational pipeline to rank variants for reassessment of unsolved rare disease patients. A co
Autor:
Benjamin H. Mullin, Rishi S. Kotecha, Emanuela Ferrari, Dave Tang, Anastasia M. Hughes, Laurence C. Cheung, Timo Lassmann, Patrycja Skut, Jiake Xu, Jennifer Tickner, Ursula R. Kees, Sébastien Malinge, Denise Anderson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The bone marrow microenvironment (BMM) plays a key role in leukemia progression, but its molecular complexity in pre-B cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children, remains poorly understood. To gain further insight,
Autor:
Raffaella Calligaris, Gilberto Pizzolato, Sara Finaurini, Piero Carninci, Lucia Antonutti, Remo Sanges, Maria Bertuzzi, Gianni Pezzoli, Dave Tang, Mauro Catalan, Stefano Goldwurm, Stefano Gustincich, Paolo Manganotti, Francesca Persichetti, Christina Vlachouli
Minisatellites, also called variable number of tandem repeats (VNTRs), are a class of repetitive elements that may affect gene expression at multiple levels and have been correlated to disease. Their identification and role as expression quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0ddb1d9bf67777d6477e203c293610
http://hdl.handle.net/20.500.11767/110181
http://hdl.handle.net/20.500.11767/110181
Autor:
Elizabeth A. Davis, Toby McLeay, Simon J. Miles, Dave Tang, Timo Lassmann, Elizabeth S. H. Scaman, Jenefer M. Blackwell, Michaela Fakiola, Heather J. Cordell, Sarra E. Jamieson, Genevieve Syn, Denise Anderson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Chronic renal disease (CRD) associated with cardiovascular disease (CVD) and/or type 2 diabetes (T2D) is a significant problem in Aboriginal Australians. Whole exome sequencing data (N = 72) showed enrichment for ClinVar pathogenic variants in gene s
Autor:
Gorjana Robevska, Kate Francis, Jocelyn van den Bergen, Katie L. Ayers, Lakshmi Nagarajan, Karen M. Rothacker, Dave Tang, Naeem Samnakay, Andrew H. Sinclair, Catherine S. Choong, Kiranjit Joshi
Publikováno v:
International Journal of Pediatric Endocrinology, Vol 2018, Iss 1, Pp 1-9 (2018)
International Journal of Pediatric Endocrinology
International Journal of Pediatric Endocrinology
Background Desert hedgehog (DHH) mutations have been described in only a limited number of individuals with 46, XY disorders of sex development (DSD) presenting as either partial or complete gonadal dysgenesis. Gonadal tumours and peripheral neuropat