Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Dave Sing"'
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Expiratory flow limitation (EFL) can be detected using oscillometric reactance and is associated with a worse clinical presentation in chronic obstructive pulmonary disease (COPD). Reactance can show negative swings upon exhalatio
Externí odkaz:
https://doaj.org/article/966b28fd33e847328e2ee5925f943241
Autor:
Phillip D. Monk, Jody L. Brookes, Victoria J. Tear, Toby N. Batten, Clare Newall, Marcin Mankowski, Michael G. Crooks, Dave Singh, Rekha Chaudhuri, Brian Leaker, Kerry Lunn, Sophie Reynolds, Sarah Dudley, Felicity J. Gabbay, Stephen T. Holgate, Ratko Djukanovic, Thomas MA Wilkinson
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Respiratory viral infections are major drivers of chronic obstructive pulmonary disease (COPD) exacerbations. Interferon-β is naturally produced in response to viral infection, limiting replication. This exploratory study aimed t
Externí odkaz:
https://doaj.org/article/0e45758b1a514217839b388bd5252764
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background COPD is associated with the development of lung cancer. A protective effect of inhaled corticosteroids (ICS) on lung cancer is still controversial. Hence, this study investigated the development of lung cancer according to inhaler
Externí odkaz:
https://doaj.org/article/0c9cc6c5df3044478a1bf4d175819819
Autor:
Salman Siddiqui, Thys van der Molen, Huib A M Kerstjens, Dave Singh, Chris Brightling, Maarten van den Berge, Alberto Papi, Klaus F Rabe, Leonardo M Fabbri, Monica Kraft, Martijn C Nawijn, Susan Muiser, Tessa M Kole
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Asthma is a heterogeneous disease with a prevalence and severity that differs between male and female patients.Question What are differences between male and female patients with asthma with regard to asthma control, lung function, inflamm
Externí odkaz:
https://doaj.org/article/9bc70945e83b454984afcfa5cfa39b16
Autor:
Zaid W. El-Husseini, Dmitry Khalenkow, Andy Lan, Thys van der Molen, Chris Brightling, Alberto Papi, Klaus F. Rabe, Salman Siddiqui, Dave Singh, Monica Kraft, Bianca Beghe, Maarten van den Berge, Djoke van Gosliga, Martijn C. Nawijn, Stefan Rose-John, Gerard H. Koppelman, Reinoud Gosens
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Asthma is stratified into type 2-high and type 2-low inflammatory phenotypes. Limited success has been achieved in developing drugs that target type 2-low inflammation. Previous studies have linked IL-6 signaling to severe asthma.
Externí odkaz:
https://doaj.org/article/e4d93162eadc447d86daca4b0d26e0df
Autor:
James Campling, Andrew Vyse, Hui-Hsuan Liu, Hannah Wright, Mary Slack, Ralf-Rene Reinert, Mark Drayson, Alex Richter, Dave Singh, Gavin Barlow, George Kassianos, Gillian Ellsbury
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 785-800 (2023)
Introduction Pneumococcal disease (PD) significantly contributes to morbidity and mortality, carrying substantial economic and public health burden. This article is a targeted review of evidence for pneumococcal vaccination in the UK, the definitions
Externí odkaz:
https://doaj.org/article/f4d32a0f961d48538c7cb07767be744f
Autor:
Elena S. Izmailova, Rachel Kilian, Jessie P. Bakker, Shawna Evans, Anthony D. Scotina, Theodore F. Reiss, Dave Singh, John A. Wagner
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 11, Pp 2112-2122 (2023)
Abstract Several inefficiencies in drug development trial implementation may be improved by moving data collection from the clinic to mobile, allowing for more frequent measurements and therefore increased statistical power while aligning to a patien
Externí odkaz:
https://doaj.org/article/5e2c9466368c4ca7864bdb4179a3d2f7
Autor:
Charlotte Davis, Dave Singh, Katie Anderson, Antonella Vardeu, Jakub Kopycinski, Alice Bridges-Webb, Alice Trickett, Susanne O’Brien, Matthew Downs, Randip Kaur, Radka Kolenovska, Louise Bussey, Kathryn Rutkowski, Sarah Sebastian, Tamsin Cargill, Eleanor Barnes, Thomas G. Evans, Paola Cicconi
Publikováno v:
Vaccines, Vol 12, Iss 6, p 644 (2024)
There are varying data concerning the effect of prior anti-vector immunity on the T-cell response induced by immunisation with an identical vectored vaccine containing a heterologous antigen insert. To determine whether prior exposure to ChAdOx1-SARS
Externí odkaz:
https://doaj.org/article/face05f3e51d423d870639594d13c324
Publikováno v:
ERJ Open Research, Vol 10, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/978656b3339f477489c81973ccdaf7a8