Zobrazeno 1 - 10
of 3 576
pro vyhledávání: '"Dave S."'
Autor:
Ronell Bridgemohan, Matthew J. Deitch, Emily Harmon, Matt R. Whiles, P. Christopher Wilson, Eban Bean, Puran Bridgemohan, Joseph H. Bisesi, Jodel Nicholas, Aaden Redhead, Dave S. Bachoon
Publikováno v:
Journal of Water and Health, Vol 22, Iss 5, Pp 923-938 (2024)
The World Health Organization classifies leptospirosis as a significant public health concern, predominantly affecting impoverished and unsanitary regions. By using the Pensacola Bay System as a case study, this study examines the underappreciated su
Externí odkaz:
https://doaj.org/article/30bdce30aa6d48e8ae7f9504e5eb9878
Autor:
Di Chen, Rui Zhang, Xiaoming Huang, Chunxia Ji, Wei Xia, Ying Qi, Xinyu Yang, Lishuang Lin, Jing Wang, Haixia Cheng, Weijun Tang, Jinhua Yu, Dave S. B. Hoon, Jun Zhang, Xin Gao, Yu Yao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background The tumor immune microenvironment can influence the prognosis and treatment response to immunotherapy. We aimed to develop a non-invasive radiomic signature in high-grade glioma (HGG) to predict the absolute density of tumor-assoc
Externí odkaz:
https://doaj.org/article/c98e5705cd594d078749ca3975601c9a
Publikováno v:
Applied and Computational Mechanics, Vol 17, Iss 2, Pp 105-120 (2023)
Gear trains are plagued by self-excited vibrations that are concentrated at the mesh frequency and its harmonics due to their varying mesh stiffness and deviations from the ideal involute profile. This is even more pronounced in spur gears due to the
Externí odkaz:
https://doaj.org/article/56c5fb6ae6964d54a10c72d6eccc1c8a
Autor:
Matias A. Bustos, Takamichi Yokoe, Yoshiaki Shoji, Yuta Kobayashi, Shodai Mizuno, Tomohiro Murakami, Xiaoqing Zhang, Sreeja C. Sekhar, SooMin Kim, Suyeon Ryu, Matthew Knarr, Steven A. Vasilev, Analisa DiFeo, Ronny Drapkin, Dave S. B. Hoon
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPi) are approved for the treatment of BRCA-mutated breast cancer (BC), including triple-negative BC (TNBC) and ovarian cancer (OvCa). A key challenge is to identify the factors associate
Externí odkaz:
https://doaj.org/article/6d8f7c8618654c2da50e93cefd679139
Autor:
Satoru Furuhashi, Matias A. Bustos, Shodai Mizuno, Suyeon Ryu, Yalda Naeini, Anton J. Bilchik, Dave S. B. Hoon
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-19 (2023)
Abstract The incidence of sporadic early-onset colon cancer (EOCC) has increased worldwide. The molecular mechanisms in the tumor and the tumor microenvironment (TME) in EOCC are not fully understood. The aim of this study is to unravel unique spatia
Externí odkaz:
https://doaj.org/article/0d6712e49e7948a8ae7537f97259d4ae
Autor:
Gino K. In, Jennifer R. Ribeiro, Jun Yin, Joanne Xiu, Matias A. Bustos, Fumito Ito, Frances Chow, Gabriel Zada, Lindsay Hwang, April K. S. Salama, Soo J. Park, Justin C. Moser, Sourat Darabi, Evidio Domingo-Musibay, Maria L. Ascierto, Kim Margolin, Jose Lutzky, Geoffrey T. Gibney, Michael B. Atkins, Benjamin Izar, Dave S. B. Hoon, Ari M. VanderWalde
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor tumor immune responses and are enriched in oxidative phosphoryla
Externí odkaz:
https://doaj.org/article/32efd05519e741b4bbdba359b3adab39
Autor:
Eric Ovruchesky, Elizabeth Pan, Melis Guer, Andrew Elliott, Shankar Siva, Praful Ravi, Bradley McGregor, Aditya Bagrodia, Ithaar Derweesh, Pedro Barata, Elisabeth I. Heath, Emmanuel S. Antonarakis, Sourat Darabi, Dave S. B. Hoon, Amir Mortazavi, Toni K. Choueiri, Chadi Nabhan, Shuanzeng Wei, Rana R. McKay
Publikováno v:
Cancers, Vol 16, Iss 10, p 1855 (2024)
Purpose: Given the emergence of PSMA-targeted diagnostic agents and therapeutics, we sought to investigate patterns of FOLH1 expression in RCC and their impacts on RCC outcomes. Methods: We conducted a pooled multi-institutional analysis of patients
Externí odkaz:
https://doaj.org/article/2eb560ab232a4717b798c1aca20ab102
Autor:
Samuel A. Kareff, Asaad Trabolsi, Harris B. Krause, Timothy Samec, Andrew Elliott, Estelamari Rodriguez, Coral Olazagasti, Dionysios C. Watson, Matias A. Bustos, Dave S. B. Hoon, Stephanie L. Graff, Emmanuel S. Antonarakis, Sanjay Goel, George Sledge, Gilberto Lopes
Publikováno v:
Cancers, Vol 16, Iss 8, p 1572 (2024)
Tipifarnib is the only targeted therapy breakthrough for HRAS-mutant (HRASmt) recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). The molecular profiles of HRASmt cancers are difficult to explore given the low frequency of HRASmt.
Externí odkaz:
https://doaj.org/article/6987b80b5782400b895a7de9fe648443
Autor:
Miles C. Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A. Creasy, Marie-Andrée Forget, Xiaoxing Yu, Xingzhi Song, Xizeng Mao, A. Gordon Robertson, Gabriele Romano, Peng Li, Elizabeth M. Burton, Yiling Lu, Robert Szczepaniak Sloane, Khalida M. Wani, Kunal Rai, Alexander J. Lazar, Lauren E. Haydu, Matias A. Bustos, Jianjun Shen, Yueping Chen, Margaret B. Morgan, Jennifer A. Wargo, Lawrence N. Kwong, Cara L. Haymaker, Elizabeth A. Grimm, Patrick Hwu, Dave S. B. Hoon, Jianhua Zhang, Jeffrey E. Gershenwald, Michael A. Davies, P. Andrew Futreal, Chantale Bernatchez, Scott E. Woodman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The regulation of the distinct intrinsic phenotypic states in melanoma remain poorly characterised. Here, multi-omics analysis for a panel of 68 early passage melanoma cell lines reveals that cancer cell intrinsic transcriptomic programs are associat
Externí odkaz:
https://doaj.org/article/96b59787498043a5a256fe86f8315695
Autor:
Shijun Ma, Yue Zhao, Wee Chyan Lee, Li-Teng Ong, Puay Leng Lee, Zemin Jiang, Gokce Oguz, Zhitong Niu, Min Liu, Jian Yuan Goh, Wenyu Wang, Matias A. Bustos, Sidse Ehmsen, Adaikalavan Ramasamy, Dave S. B. Hoon, Henrik J. Ditzel, Ern Yu Tan, Qingfeng Chen, Qiang Yu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Hypoxia can promote tumor escape from immune surveillance and immunotherapy. Here, the authors show that hypoxia induces T and NK cell dysfunction through HIF1α-mediated epigenetic suppression of effector gene expression, conferring resistance to an
Externí odkaz:
https://doaj.org/article/f4d636bacf6c468fb0de459e001bd7f5