Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Dave S B, Hoon"'
Autor:
Di Chen, Rui Zhang, Xiaoming Huang, Chunxia Ji, Wei Xia, Ying Qi, Xinyu Yang, Lishuang Lin, Jing Wang, Haixia Cheng, Weijun Tang, Jinhua Yu, Dave S. B. Hoon, Jun Zhang, Xin Gao, Yu Yao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background The tumor immune microenvironment can influence the prognosis and treatment response to immunotherapy. We aimed to develop a non-invasive radiomic signature in high-grade glioma (HGG) to predict the absolute density of tumor-assoc
Externí odkaz:
https://doaj.org/article/c98e5705cd594d078749ca3975601c9a
Autor:
Matias A. Bustos, Takamichi Yokoe, Yoshiaki Shoji, Yuta Kobayashi, Shodai Mizuno, Tomohiro Murakami, Xiaoqing Zhang, Sreeja C. Sekhar, SooMin Kim, Suyeon Ryu, Matthew Knarr, Steven A. Vasilev, Analisa DiFeo, Ronny Drapkin, Dave S. B. Hoon
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPi) are approved for the treatment of BRCA-mutated breast cancer (BC), including triple-negative BC (TNBC) and ovarian cancer (OvCa). A key challenge is to identify the factors associate
Externí odkaz:
https://doaj.org/article/6d8f7c8618654c2da50e93cefd679139
Autor:
Satoru Furuhashi, Matias A. Bustos, Shodai Mizuno, Suyeon Ryu, Yalda Naeini, Anton J. Bilchik, Dave S. B. Hoon
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-19 (2023)
Abstract The incidence of sporadic early-onset colon cancer (EOCC) has increased worldwide. The molecular mechanisms in the tumor and the tumor microenvironment (TME) in EOCC are not fully understood. The aim of this study is to unravel unique spatia
Externí odkaz:
https://doaj.org/article/0d6712e49e7948a8ae7537f97259d4ae
Autor:
Gino K. In, Jennifer R. Ribeiro, Jun Yin, Joanne Xiu, Matias A. Bustos, Fumito Ito, Frances Chow, Gabriel Zada, Lindsay Hwang, April K. S. Salama, Soo J. Park, Justin C. Moser, Sourat Darabi, Evidio Domingo-Musibay, Maria L. Ascierto, Kim Margolin, Jose Lutzky, Geoffrey T. Gibney, Michael B. Atkins, Benjamin Izar, Dave S. B. Hoon, Ari M. VanderWalde
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor tumor immune responses and are enriched in oxidative phosphoryla
Externí odkaz:
https://doaj.org/article/32efd05519e741b4bbdba359b3adab39
Autor:
Miles C. Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A. Creasy, Marie-Andrée Forget, Xiaoxing Yu, Xingzhi Song, Xizeng Mao, A. Gordon Robertson, Gabriele Romano, Peng Li, Elizabeth M. Burton, Yiling Lu, Robert Szczepaniak Sloane, Khalida M. Wani, Kunal Rai, Alexander J. Lazar, Lauren E. Haydu, Matias A. Bustos, Jianjun Shen, Yueping Chen, Margaret B. Morgan, Jennifer A. Wargo, Lawrence N. Kwong, Cara L. Haymaker, Elizabeth A. Grimm, Patrick Hwu, Dave S. B. Hoon, Jianhua Zhang, Jeffrey E. Gershenwald, Michael A. Davies, P. Andrew Futreal, Chantale Bernatchez, Scott E. Woodman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The regulation of the distinct intrinsic phenotypic states in melanoma remain poorly characterised. Here, multi-omics analysis for a panel of 68 early passage melanoma cell lines reveals that cancer cell intrinsic transcriptomic programs are associat
Externí odkaz:
https://doaj.org/article/96b59787498043a5a256fe86f8315695
Autor:
Shijun Ma, Yue Zhao, Wee Chyan Lee, Li-Teng Ong, Puay Leng Lee, Zemin Jiang, Gokce Oguz, Zhitong Niu, Min Liu, Jian Yuan Goh, Wenyu Wang, Matias A. Bustos, Sidse Ehmsen, Adaikalavan Ramasamy, Dave S. B. Hoon, Henrik J. Ditzel, Ern Yu Tan, Qingfeng Chen, Qiang Yu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Hypoxia can promote tumor escape from immune surveillance and immunotherapy. Here, the authors show that hypoxia induces T and NK cell dysfunction through HIF1α-mediated epigenetic suppression of effector gene expression, conferring resistance to an
Externí odkaz:
https://doaj.org/article/f4d636bacf6c468fb0de459e001bd7f5
Autor:
Yasunari Fukuda, Matias A. Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M. Lopez, Jared K. Burks, Jeffrey E. Lee, Elizabeth A. Grimm, Dave S. B. Hoon, Suhendan Ekmekcioglu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-11 (2022)
Abstract Soluble forms of receptors play distinctive roles in modulating signal-transduction pathways. Soluble CD74 (sCD74) has been identified in sera of inflammatory diseases and implicated in their pathophysiology; however, few relevant data are a
Externí odkaz:
https://doaj.org/article/140d1bf9c59b46fe8fac11763cb01977
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/f8a7141cc6f34f7aa02ba0c46e4661a0
Autor:
Yasunari Fukuda, Matias A. Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M. Lopez, Jared K. Burks, Jeffrey E. Lee, Elizabeth A. Grimm, Dave S. B. Hoon, Suhendan Ekmekcioglu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/42b64f33aaa74cc386ffcfd4f2939ee4
Autor:
Yoshiaki Shoji, Takamichi Yokoe, Yuta Kobayashi, Tomohiro Murakami, Peter J. Bostick, Yosef Shiloh, Dave S. B. Hoon, Matias A. Bustos
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/79dba0f7ed4149d59cbe086b6003269e