Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dave Klenerman"'
Autor:
Srinjan Basu, Lisa-Maria Needham, David Lando, Edward J. R. Taylor, Kai J. Wohlfahrt, Devina Shah, Wayne Boucher, Yi Lei Tan, Lawrence E. Bates, Olga Tkachenko, Julie Cramard, B. Christoffer Lagerholm, Christian Eggeling, Brian Hendrich, Dave Klenerman, Steven F. Lee, Ernest D. Laue
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Single molecule tracking of fluorescent proteins in live cells is temporally limited by fluorophore photobleaching. Here the authors show using fluorophore pairs that FRET competes with photobleaching to improve photostability and allow longer-term t
Externí odkaz:
https://doaj.org/article/4ba0bd5ae2024d44b50386dc802df3dc
Autor:
Andy Riddell, Tim J. Stevens, Dave Klenerman, Martin Leeb, Steven F. Lee, Brian Hendrich, Kai J. Wohlfahrt, Wayne Boucher, Srinjan Basu, Liam P Atkinson, Yang Cao, Ernest D. Laue, David Lando
Fluorescence imaging and chromosome conformation capture assays such as Hi-C are key tools for studying genome organization. However, traditionally, they have been carried out independently, making integration of the two types of data difficult to pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a52f6d57103557e2a3142d068e0ad8
Autor:
James Stephenson, Dave Klenerman, Julia C. Kenyon, Haitao Li, Andrew M. L. Lever, Martyn F. Symmons
Publikováno v:
Structure(London, England:1993)
Summary HIV-1 genomic RNA has a noncoding 5′ region containing sequential conserved structural motifs that control many parts of the life cycle. Very limited data exist on their three-dimensional (3D) conformation and, hence, how they work structur
Autor:
Luciano Di Croce, Julie Cramard, Aoife O’Shaughnessy-Kirwan, Andre J. Faure, Miriam Sansó, Tim J. Stevens, Martin Leeb, Ben Lehner, Anton Wutz, David Lando, Kai J. Wohlfahrt, Brian Hendrich, Steven F. Lee, Yang Cao, Dave Klenerman, Srinjan Basu, Ernest D. Laue, Enrique Blanco, Lluis Morey, Meryem Ralser, Wayne Boucher, Liam P Atkinson, Matthieu Palayret
Publikováno v:
Nature
The folding of genomic DNA from the beads-on-a-string-like structure of nucleosomes into higher-order assemblies is crucially linked to nuclear processes. Here we calculate 3D structures of entire mammalian genomes using data from a new chromosome co
Autor:
James McCol, Dave Klenerman, Ji-Eun Lee, Steven F. Lee, Simon J. Davis, Ana Filipa L.O.M. Santos, Aleks Ponjavic, Alexander R. Carr
Publikováno v:
Biophysical Journal. 110:485a
Most optical imaging of individual cells has been conducted in 2D on flat glass or culture plastic. Not only is this very abstract from the biological environment and does not imitate physiological conditions, but it may lead to unwanted perturbation