Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dave Farr"'
Publikováno v:
Journal of Advanced Nursing. 62:562-571
Title. A unique practice model for Nurse Practitioners in long-term care homes Aim. This paper is a report of a study examining a practice model for Nurse Practitioners (NPs) working in long-term care (LTC) homes and its impact on staff confidence, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cfc2e2f5508d7a58b57feb5c83cbe2
https://doi.org/10.1111/j.1365-2648.2008.04628.x
https://doi.org/10.1111/j.1365-2648.2008.04628.x
Autor:
Darryl Brynley Jones, Karen Dunnet, John Ambler, Lyndon Nigel Brown, Diana Janus, Garrick Smith, Dave Bentley, Mark Mercer, Keith Menear, Dave Farr, K D Butler, Paul Butler, Morris Tweed, Emma Baker, Mark Talbot, Darren Le Grand, Judy Hayler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:737-742
The application of selection criteria, based on potency and physicochemical parameters, to a candidate library of thrombin inhibitors is described. The utility of the approach is exemplified by the discovery of a potent, selective and bioavailable th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b71e74af7c3708ef01cda36045d1146
https://doi.org/10.1016/s0960-894x(99)00061-x
https://doi.org/10.1016/s0960-894x(99)00061-x
Autor:
Lyndon Nigel Brown, Keith Menear, Dave Farr, Darren Le Grand, Morris Tweed, John Ambler, Karen Dunnet, Mark Mercer, Diana Janus, Bernard Wathey, David Bentley, Mark Talbot
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(8)
Thrombin inhibitors have been designed with the replacement of the strongly basic guanidine P1 pharmocophore with a group that exploits the lipophilicity of the S1 pocket. The approach has lead to the discovery of potent thrombin inhibitors demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2adac2f91335be131c61084027db0e
https://pubmed.ncbi.nlm.nih.gov/10328293
https://pubmed.ncbi.nlm.nih.gov/10328293
Autor:
Karen Dunnet, Garrick Smith, Darren Le Grand, John Ambler, Keith Menear, Mark Mercer, Diana Janus, Dave Farr, Mark Talbot, Paul Butler, Darryl Brynley Jones, Lyndon Nigel Brown, Emma Baker, Morris Tweed
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(24)
The chemical optimisation of CGH1668 1 is described employing an in vivo model of absorption to determine the influence on bioavailability of single point modifications to five key molecular templates. The discovery of an orally bioavailable and sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b465f25cea0a8b6bb45beff4ef05ca66
https://pubmed.ncbi.nlm.nih.gov/9934475
https://pubmed.ncbi.nlm.nih.gov/9934475