Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dave Beare"'
Autor:
Peter J. Campbell, Elisabeth Dawson, Peter Fish, Claire Rye, Dave Beare, Sari Ward, Nidhi Bindal, Simon A. Forbes, Sam Thompson, Sally Bamford, Bhavana Harsha, Laura Ponting, Raymund Stefancsik, Charambulos Boutselakis, John Tate, Shicai Wang, Chris Ramshaw, Charlotte G. Cole, Chai Yin Kok, Harry Jubb, Zbyslaw Sondka
Publikováno v:
Cancer Research. 78:3284-3284
COSMIC, the Catalogue Of Somatic Mutations In Cancer (http://cancer.sanger.ac.uk/cosmic) is a long-term sustainable effort to collect, standardise and integrate information on somatic mutations and other molecular alterations that cause human cancer.
Autor:
Sara Widaa, Michael R. Stratton, Adam Butler, Sarah Edkins, Thomas Santarius, P. Andy Futreal, Lina Chen, Jon Hinton, Dave Beare, Sajani Swamy, Christopher Greenman, Graham R. Bignell
Publikováno v:
Biostatistics (Oxford, England)
High-throughput oligonucleotide microarrays are commonly employed to investigate genetic disease, including cancer. The algorithms employed to extract genotypes and copy number variation function optimally for diploid genomes usually associated with
Autor:
Lucy Stebbings, Syd Barthorpe, Sarah O’Meara, Michael R. Stratton, Richard J. Kahnoski, Lee Mulderrig, Bin Tean Teh, Ronald A. DePinho, Laura Mudie, Mark Maddison, Catherine Leroy, Giovanni Tonon, Philip J. Stephens, Jenny Andrews, David J. McBride, Yu-Tzu Tai, John Wong, Sok Kean Khoo, Meng-Lay Lin, Tatiana Mironenko, Aaron Massie, Claire Hardy, Rachel Turner, David T. Jones, Calli Latimer, Jennifer Cole, Sarah Edkins, Dave Beare, Sofie West, Peter J. Campbell, V. Peter Collins, Helen Davies, Sara Widaa, Graham R. Bignell, Mingming Jia, Patrick S. Tarpey, Gijs van Haaften, Jennifer Varian, Gurpreet Tang, Adam Butler, Chai Yin Kok, Simon Law, Gillian L. Dalgliesh, Raffaella Smith, Koichi Ichimura, Rebecca Shepherd, Jon W. Teague, Erin Pleasance, Kirsten McLay, Simon Maquire, Gemma Buck, Suet Yi Leung, Paul Wray, Andrew Menzies, Simon A. Forbes, Christopher Greenman, P. Andrew Futreal, Kelly Turrell, Jonathan Hinton, Lina Chen, Siu Tsan Yuen, Kenneth C. Anderson
Publikováno v:
Nature genetics
Somatically acquired epigenetic changes are present in many cancers. Epigenetic regulation is maintained via post-translational modifications of core histones. Here, we describe inactivating somatic mutations in the histone lysine demethylase gene UT
Autor:
Daniel A. Haber, Patricia Greninger, Cyril H. Benes, Howard Lightfoot, Simon A. Forbes, James Smith, Jorge Soares, Sridhar Ramaswamy, P. Andrew Futreal, I. Richard Thompson, Ultan McDermott, Michael R. Stratton, Mathew J. Garnett, Elena J. Edelman, Wanjuan Yang, Dave Beare, Nidhi Bindal
Publikováno v:
Nucleic Acids Research
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest publi
Autor:
Lina Chen, Mingming Jia, Mark Maddison, Claire Hardy, Henry Knott, Jenny Andrews, Bill Wondergem, Karl Dykema, Patrick S. Tarpey, Syd Barthorpe, Meng-Lay Lin, Michael R. Stratton, Sok Kean Khoo, Lucy Stebbings, Sarah Edkins, Laura Mudie, Gemma Buck, Adam Butler, Calli Latimer, Helen Davies, Tatiana Mironenko, David Petillo, David T. Jones, John Anema, Jon W. Teague, Bin Tean Teh, Dave Beare, Simon A. Forbes, Catherine Leroy, Kirsten McLay, Simon Maguire, Gurpreet Tang, Kelly Turrell, P. Andrew Futreal, Graham R. Bignell, Aarjunan Rajasingham, David J. McBride, King Wai Lau, Christopher Greenman, Erin Pleasance, Chai Yin Kok, Andrew Menzies, Richard J. Kahnoski, Gillian L. Dalgliesh, Raffaella Smith, Peter J. Campbell, Rebecca Shepherd, Philip J. Stephens, Lee Mulderrig, Kyle A. Furge, Sarah O’Meara
Publikováno v:
Nature. 463(7279)
Clear cell renal cell carcinoma (ccRCC) is the most common form of adult kidney cancer, characterized by the presence of inactivating mutations in the VHL gene in most cases, and by infrequent somatic mutations in known cancer genes. To determine fur
Autor:
Sally Bamford, Michael R. Stratton, Kenric Leung, Charlotte G. Cole, Mingming Jia, Prasad Gunasekaran, Dave Beare, Simon A. Forbes, Minjie Ding, Nidhi Bindal, Chai Yin Kok, Tisham De, Charambulos Boutselakis, Sari Ward, Peter J. Campbell, Jon W. Teague
Publikováno v:
Cancer Research. 75:62-62
COSMIC, the Catalogue Of Somatic Mutations In Cancer (http://cancer.sanger.ac.uk) is the world's largest and most comprehensive online resource for exploring the impact of somatic mutations in human cancer. Live since 2004, the 71st release (Nov 2014