Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial.

Autor: Ortigoza MB; Division of Infectious Disease, Department of Medicine, NYU Grossman School of Medicine, New York, New York.; Department of Microbiology, NYU Grossman School of Medicine, New York, New York., Yoon H; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York., Goldfeld KS; Department of Population Health, NYU Grossman School of Medicine, New York, New York., Troxel AB; Department of Population Health, NYU Grossman School of Medicine, New York, New York., Daily JP; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York., Wu Y; Department of Population Health, NYU Grossman School of Medicine, New York, New York., Li Y; Department of Population Health, NYU Grossman School of Medicine, New York, New York., Wu D; Department of Population Health, NYU Grossman School of Medicine, New York, New York., Cobb GF; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Baptiste G; Department of Surgery, NYU Grossman School of Medicine, New York, New York., O'Keeffe M; Department of Medicine, NYU Long Island School of Medicine, Mineola, New York., Corpuz MO; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York., Ostrosky-Zeichner L; Division of Infectious Disease, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Amin A; Department of Emergency Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Zacharioudakis IM; Division of Infectious Disease, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Jayaweera DT; Division of Infectious Disease, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida.; Miami Clinical and Translational Science Institute, University of Miami Miller School of Medicine Miami, Florida., Wu Y; Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida., Philley JV; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, The University of Texas Health Science Center at Tyler, UTHealth East Texas, Tyler., Devine MS; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, The University of Texas Health Science Center at Tyler, UTHealth East Texas, Tyler., Desruisseaux MS; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut., Anjan S; Division of Infectious Disease, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida., Mathew R; Division of Critical Care, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Patel B; Division of Critical Care, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Nigo M; Division of Infectious Disease, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Upadhyay R; Department of Medicine, NYU Grossman School of Medicine, New York, New York.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, New York., Kupferman T; Division of Infectious Disease, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Dentino AN; Department of Internal Medicine, The University of Texas Rio Grande Valley, Edinburg., Nanchal R; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee., Merlo CA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland., Hager DN; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland., Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York., Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York., Rivera J; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York., Bikash CR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York., Lasso G; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York., Hilbert TP; Department of Pathology, NYU Grossman School of Medicine, New York, New York., Paroder M; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York., Asencio AA; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York., Liu M; Department of Population Health, NYU Grossman School of Medicine, New York, New York.; Department of Environmental Health, NYU Grossman School of Medicine, New York, New York., Petkova E; Department of Population Health, NYU Grossman School of Medicine, New York, New York.; Department of Child and Adolescent Psychiatry, NYU Grossman School of Medicine, New York.; Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York., Bragat A; Clinical Research Information Technology and Informatics, NYU Grossman School of Medicine, New York, New York., Shaker R; Clinical and Translational Science Institute of Southern Wisconsin, Medical College of Wisconsin Milwaukee., McPherson DD; Center for Clinical and Translational Sciences, Division of Cardiovascular Medicine, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Sacco RL; Miami Clinical and Translational Science Institute, University of Miami Miller School of Medicine Miami, Florida., Keller MJ; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.; Harold and Muriel Block Institute for Clinical and Translational Research, Albert Einstein College of Medicine and Montefiore Medical Center Bronx, New York., Grudzen CR; Ronald O. Perelman Department of Emergency Medicine, NYU Grossman School of Medicine, New York, New York.; NYC Health and Hospitals Corporation Clinical and Translational Science Institute, NYU Grossman School of Medicine, New York, New York., Hochman JS; NYC Health and Hospitals Corporation Clinical and Translational Science Institute, NYU Grossman School of Medicine, New York, New York.; Leon H. Charney Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Pirofski LA; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York., Parameswaran L; Division of Infectious Disease, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Corcoran AT; Department of Urology, NYU Long Island School of Medicine, Mineola, New York., Rohatgi A; Department of Medicine, NYU Long Island School of Medicine, Mineola, New York., Wronska MW; Department of Medicine, NYU Long Island School of Medicine, Mineola, New York., Wu X; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Srinivasan R; Department of Pediatrics, NYU Grossman School of Medicine, New York, New York., Deng FM; Department of Pathology, NYU Grossman School of Medicine, New York, New York., Filardo TD; Division of Infectious Disease, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Pendse J; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Blaser SB; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Whyte O; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Gallagher JM; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Thomas OE; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Ramos D; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Sturm-Reganato CL; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Fong CC; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Daus IM; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Payoen AG; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Chiofolo JT; Department of Pathology, NYU Long Island School of Medicine, Mineola, New York., Friedman MT; Department of Pathology, NYU Long Island School of Medicine, Mineola, New York., Wu DW; Department of Pathology, NYU Grossman School of Medicine, New York, New York., Jacobson JL; Department of Pathology, NYU Grossman School of Medicine, New York, New York., Schneider JG; Department of Medicine, NYU Long Island School of Medicine, Mineola, New York., Sarwar UN; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.; Pfizer Vaccine Clinical Research and Development, Pfizer Inc, Pearl River, New York., Wang HE; Department of Emergency Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston.; Department of Emergency Medicine, The Ohio State University, Ohio., Huebinger RM; Department of Emergency Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Dronavalli G; Division of Critical Care, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Bai Y; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Grimes CZ; Division of Infectious Disease, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Eldin KW; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Umana VE; Division of Infectious Disease, Department of Internal Medicine, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston., Martin JG; Department of Internal Medicine, The University of Texas Rio Grande Valley, Edinburg., Heath TR; Department of Internal Medicine, The University of Texas Rio Grande Valley, Edinburg., Bello FO; Department of Internal Medicine, The University of Texas Rio Grande Valley, Edinburg., Ransford DL; Miami Clinical and Translational Science Institute, University of Miami Miller School of Medicine Miami, Florida., Laurent-Rolle M; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Shenoi SV; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Akide-Ndunge OB; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Thapa B; Department of Medicine, Medical College of Wisconsin, Milwaukee., Peterson JL; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee., Knauf K; Clinical and Translational Science Institute of Southern Wisconsin, Medical College of Wisconsin Milwaukee., Patel SU; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland., Cheney LL; Division of Infectious Disease, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York., Tormey CA; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut., Hendrickson JE; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.; Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.

Publikováno v: JAMA internal medicine [JAMA Intern Med] 2022 Feb 01; Vol. 182 (2), pp. 115-126.