Identification and Development of Therapeutics for COVID-19

Autor: Rando, Halie M., Wellhausen, Nils, Ghosh, Soumita, Lee, Alexandra J., Dattoli, Anna Ada, Hu, Fengling, Byrd, James Brian, Rafizadeh, Diane N., Lordan, Ronan, Qi, Yanjun, Sun, Yuchen, Brueffer, Christian, Field, Jeffrey M., Guebila, Marouen Ben, Jadavji, Nafisa M., Skelly, Ashwin N., Ramsundar, Bharath, Wang, Jinhui, Goel, Rishi Raj, Park, YoSon, Consortium, the COVID-19 Review, Boca, Simina M., Gitter, Anthony, Greene, Casey S.

After emerging in China in late 2019, the novel Severe acute respiratory syndrome-like coronavirus 2 (SARS-CoV-2) spread worldwide and as of early 2021, continues to significantly impact most countries. Only a small number of coronaviruses are known

Externí odkaz: http://arxiv.org/abs/2103.02723

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Identification and Development of Therapeutics for COVID-19.

Autor: Rando HM; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, United States of America; Center for Health AI, University of Colorado School of Medicine, Aurora, Colorado, United States of America · Funded by the Gordon and Betty Moore Foundation (GBMF 4552)., Wellhausen N; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Ghosh S; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Lee AJ; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America · Funded by the Gordon and Betty Moore Foundation (GBMF 4552)., Dattoli AA; Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Hu F; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Byrd JB; University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America · Funded by NIH K23HL128909; FastGrants., Rafizadeh DN; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of AmericaFunded by NIH Medical Scientist Training Program T32 GM07170., Lordan R; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5158, USA., Qi Y; Department of Computer Science, University of Virginia, Charlottesville, VA, United States of America., Sun Y; Department of Computer Science, University of Virginia, Charlottesville, VA, United States of America., Brueffer C; Department of Clinical Sciences, Lund University, Lund, Sweden., Field JM; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Guebila MB; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America., Jadavji NM; Biomedical Science, Midwestern University, Glendale, AZ, United States of America; Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada · Funded by the American Heart Association (20AIREA35050015)., Skelly AN; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States of America · Funded by NIH Medical Scientist Training Program T32 GM07170., Ramsundar B; The DeepChem Project, https://deepchem.io/., Wang J; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Goel RR; Institute for Immunology, University of Pennsylvania, Philadelphia, PA, United States of America., Park Y; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America · Funded by NHGRI R01 HG10067., Boca SM; Innovation Center for Biomedical Informatics, Georgetown University Medical Center, Washington, District of Columbia, United States of America; Early Biometrics & Statistical Innovation, Data Science & Artificial Intelligence, R & D, AstraZeneca, Gaithersburg, Maryland, United States of America., Gitter A; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America; Morgridge Institute for Research, Madison, Wisconsin, United States of America · Funded by John W. and Jeanne M. Rowe Center for Research in Virology., Greene CS; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America; Childhood Cancer Data Lab, Alex's Lemonade Stand Foundation, Philadelphia, Pennsylvania, United States of America; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, United States of America; Center for Health AI, University of Colorado School of Medicine, Aurora, Colorado, United States of America · Funded by the Gordon and Betty Moore Foundation (GBMF 4552); the National Human Genome Research Institute (R01 HG010067).

Publikováno v: ArXiv [ArXiv] 2021 Mar 03. Date of Electronic Publication: 2021 Mar 03.