Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Dasom Mun"'
Autor:
Dasom Mun, Ji-Young Kang, Malgeum Park, Gyeongseo Yoo, Hyoeun Kim, Nuri Yun, You Mi Hwang, Boyoung Joung
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103592- (2024)
Long QT syndrome type 2 (LQT2) is a heart disorder resulting from a loss-of-function mutation in the KCNH2 gene that causes loss of Kv11.1 channel function, potentially resulting in syncope, arrhythmias, and sudden death. We derived induced pluripote
Externí odkaz:
https://doaj.org/article/eff471611fdb4b298b86d7cf4a3f0d1a
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 10, Pp n/a-n/a (2023)
Abstract Small‐interfering RNA (siRNA) therapy is considered a powerful therapeutic strategy for treating cardiac hypertrophy, an important risk factor for subsequent cardiac morbidity and mortality. However, the lack of safe and efficient in vivo
Externí odkaz:
https://doaj.org/article/2909577102da499dab43f699f339d248
Generation of two PITX2 knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system
Autor:
Dasom Mun, Ji-Young Kang, Yumin Chun, Da-Seul Park, Hyoeun Kim, Nuri Yun, Seung-Hyun Lee, Boyoung Joung
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102940- (2022)
PITX2 is a homeobox gene located in the human 4q25 locus and is commonly associated with atrial fibrillation (AF). Here, we generated two PITX2 knock-out human induced pluripotent stem cell (iPSC) lines using CRISPR/Cas9 genome editing. The edited iP
Externí odkaz:
https://doaj.org/article/728513e601b34ec4b017545106bd69c1
Generation of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system
Autor:
Ji-Young Kang, Dasom Mun, Yumin Chun, Da-Seul Park, Hyoeun Kim, Nuri Yun, Seung-Hyun Lee, Boyoung Joung
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102901- (2022)
TTN mutations are the common genetic cause for various types of cardiomyopathies (e.g., dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy) and skeletal myopathies. Her
Externí odkaz:
https://doaj.org/article/e8b63f964ebf401b8c6c3f49883d1327
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 1024-1032 (2021)
Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by cells, with important roles in physiological and pathological processes. Recent research has established the application of sEVs as therapeutic vehicles in variou
Externí odkaz:
https://doaj.org/article/5120cedaa63d4a62a422f0793d41c06a
Publikováno v:
Stem Cell Research, Vol 63, Iss , Pp 102878- (2022)
E192K missense mutation of TPM1 has been found in different types of cardiomyopathies (e.g., hypertrophic cardiomyopathy, dilated cardiomyopathy, and left ventricular non-compaction), leading to systolic dysfunction, diastolic dysfunction, and/or tac
Externí odkaz:
https://doaj.org/article/1a1f28a69b3b4ac086927170d25560ce
Publikováno v:
Heart Rhythm. 19:1450-1458
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d6836e069c378fd31b27ed267135ab
https://doi.org/10.1016/j.hrthm.2022.05.033
https://doi.org/10.1016/j.hrthm.2022.05.033
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220036 (2019)
Exosomes might have an unimproved potential to serve as effective delivery vehicles. However, when exosomes are developed for therapeutic applications, a method to enhance their delivery is important. This study aimed to evaluate wheather calcium chl
Externí odkaz:
https://doaj.org/article/eaf579bb3d774b3d97491559b2de6571
Publikováno v:
Clinical Science. 136:621-637
Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles that contribute to the pathogenesis of atrial fibrillation (AF). Here, we investigated the role of sEVs derived from patients with persistent AF in the pathophysiology of AF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d728d2f2e677118d2c47447640be4e15
https://doi.org/10.1042/cs20211141
https://doi.org/10.1042/cs20211141
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss, Pp 1024-1032 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by cells, with important roles in physiological and pathological processes. Recent research has established the application of sEVs as therapeutic vehicles in variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd70850becebb5e377a3c62a45ef54b8
http://www.sciencedirect.com/science/article/pii/S2162253121001128
http://www.sciencedirect.com/science/article/pii/S2162253121001128