Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Dashuang, Shi"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Plasmodium falciparum harbors group 1 and group 2 chaperonin systems to mediate the folding of cellular proteins in different cellular locations. Two distinct group 1 chaperonins operate in the organelles of mitochondria and apicoplasts, whi
Externí odkaz:
https://doaj.org/article/b980ac26f71944b9a0f7ac229bc5e405
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 18836-18864 (2015)
Enzymes in the transcarbamylase family catalyze the transfer of a carbamyl group from carbamyl phosphate (CP) to an amino group of a second substrate. The two best-characterized members, aspartate transcarbamylase (ATCase) and ornithine transcarbamyl
Externí odkaz:
https://doaj.org/article/1f0e2333bc3b4b179cd805150746a72b
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13004-13022 (2015)
N-acetylglutamate synthase (NAGS) catalyzes the production of N-acetylglutamate (NAG) from acetyl-CoA and l-glutamate. In microorganisms and plants, the enzyme functions in the arginine biosynthetic pathway, while in mammals, its major role is to pro
Externí odkaz:
https://doaj.org/article/5863ea3e44744be593a8cf47cbec30d0
Publikováno v:
Biology, Vol 7, Iss 2, p 34 (2018)
Carbamyl phosphate (CP) is well-known as an essential intermediate of pyrimidine and arginine/urea biosynthesis. Chemically, CP can be easily synthesized from dihydrogen phosphate and cyanate. Enzymatically, CP can be synthesized using three differen
Externí odkaz:
https://doaj.org/article/4b2a0128c94740dabc8a4d4d937bb075
Autor:
Abhishek Santra, Teri J. Slack, Hai Yu, Dashuang Shi, Musleh M. Muthana, Wanqing Li, Yang Liu, Xi Chen
Publikováno v:
The Journal of organic chemistry, vol 84, iss 11
J Org Chem
J Org Chem
A library of 2(e),3(a/e)-difluorosialic acids and their C-5 and/or C-9 derivatives were chemoenzymatically synthesized. Pasteurella multocida sialic acid aldolase (PmAldolase), but not its Escherichia coli homolog (EcAldolase), was found to catalyze
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Plasmodium falciparum harbors group 1 and group 2 chaperonin systems to mediate the folding of cellular proteins in different cellular locations. Two distinct group 1 chaperonins operate in the organelles of mitochondria and apicoplasts, while group
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70369 (2013)
N-acetylglutamate synthase (NAGS) catalyzes the conversion of AcCoA and L-glutamate to CoA and N-acetyl-L-glutamate (NAG), an obligate cofactor for carbamyl phosphate synthetase I (CPSI) in the urea cycle. NAGS deficiency results in elevated levels o
Externí odkaz:
https://doaj.org/article/c04939634cc44988a43f269b9a8255cd
Autor:
Jianhua Wei, Yang Xue, Lian Wu, Jie Ma, Xiuli Yi, Junrui Zhang, Bin Lu, Chunying Li, Dashuang Shi, Songtao Shi, Xinghua Feng, Tao Cai
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35337 (2012)
EEC (ectrodactyly, ectodermal dysplasia, clefting; OMIM 604292) is an autosomal dominant developmental disorder resulting mainly from pathogenic mutations of the DNA-binding domain (DBD) of the TP63 gene. In this study, we showed that K193E mutation
Externí odkaz:
https://doaj.org/article/c1798ad77a0247319e5ee2747df6a1d2
Autor:
Dashuang Shi, Yongdong Li, Juan Cabrera-Luque, Zhongmin Jin, Xiaolin Yu, Gengxiang Zhao, Nantaporn Haskins, Norma M Allewell, Mendel Tuchman
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28825 (2011)
Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, we
Externí odkaz:
https://doaj.org/article/de8dae987bdc4042b99fb83b43ae9ad3
Autor:
Hai Yu, Gengxiang Zhao, Yang Liu, Xi Chen, Teri J. Slack, Dashuang Shi, John B. McArthur, An Xiao, Zahra Khedri, Yanhong Li, Wanqing Li
Publikováno v:
Bioorganic & medicinal chemistry, vol 26, iss 21
Sialidases or neuraminidases are enzymes that catalyze the cleavage of terminal sialic acids from oligosaccharides and glycoconjugates. They play important roles in bacterial and viral infection and have been attractive targets for drug development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c459c65aaf167265104cef103341765d
https://escholarship.org/uc/item/3dr8f40t
https://escholarship.org/uc/item/3dr8f40t