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of 10
pro vyhledávání: '"Daryn K. Cass"'
Autor:
Kuei Y Tseng, Adriana Caballero, Alexander Dec, Daryn K Cass, Natalie Simak, Elizabeth Sunu, Michael J Park, Shannon R Blume, Stephen Sammut, Diana J Park, Anthony R West
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27187 (2011)
There is clearly a necessity to identify novel non-dopaminergic mechanisms as new therapeutic targets for Parkinson's disease (PD). Among these, the soluble guanylyl cyclase (sGC)-cGMP signaling cascade is emerging as a promising candidate for second
Externí odkaz:
https://doaj.org/article/f50c637644c14cd78b916f8abbf67d55
Autor:
Ajay Bhandari, John P. Bruno, Robert Schwarcz, Kuei Y. Tseng, Daniel R. Thomases, Daryn K. Cass, Eden Flores-Barrera
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(33)
Increased concentrations of kynurenic acid (KYNA) in the prefrontal cortex (PFC) are thought to contribute to the development of cognitive deficits observed in schizophrenia. Although this view is consistent with preclinical studies showing a negativ
Autor:
Daniel R. Thomases, Kuei Y. Tseng, Li-Jun Heng, Eden Flores-Barrera, Daryn K. Cass, Adriana Caballero
Publikováno v:
Biological Psychiatry. 75:508-516
Background Refinement of mature cognitive functions, such as working memory and decision making, typically takes place during adolescence. The acquisition of these functions is linked to the protracted development of the prefrontal cortex (PFC) and d
Publikováno v:
Biological Psychiatry. 74:490-501
Background Drug experimentation during adolescence is associated with increased risk of drug addiction relative to any other age group. To further understand the neurobiology underlying such liability, we investigate how early adolescent cocaine expe
Publikováno v:
Psychopharmacology. 231:1789-1796
The prefrontal cortex (PFC) receives multiple cortical and subcortical afferents that regulate higher order cognitive functions, many of which emerge late in adolescence. However, it remains unclear how these afferents influence PFC processing, espec
Publikováno v:
Brain Structure and Function. 219:395-406
Determining the normal developmental trajectory of individual GABAergic components in the prefrontal cortex (PFC) during the adolescent transition period is critical because local GABAergic interneurons are thought to play an important role in the fu
The adolescent susceptibility to the onset of psychiatric disorders is only beginning to be understood when factoring in the development of the prefrontal cortex (PFC). The functional maturation of the PFC is dependent upon proper integration of glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c638af92298cbddbf8f6f4705cd7a6
https://europepmc.org/articles/PMC4078083/
https://europepmc.org/articles/PMC4078083/
Autor:
Kuei Y. Tseng, Eden Flores-Barrera, Daryn K. Cass, Daniel R. Thomases, Adriana Caballero, Webster F. Vital
Publikováno v:
Molecular psychiatry
Converging epidemiological studies indicate that cannabis abuse during adolescence increases the risk of developing psychosis and prefrontal cortex (PFC)-dependent cognitive impairments later in life. However, the mechanisms underlying the adolescent
Autor:
Daryn K. Cass, Stephen Sammut, Shannon R. Blume, Anthony R. West, Elizabeth Sunu, Kuei Y. Tseng, Adriana Caballero, Natalie Simak, Michael J. Park, Diana J. Park, Alexander M. Dec
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 11, p e27187 (2011)
PLoS ONE, Vol 6, Iss 11, p e27187 (2011)
Objective There is clearly a necessity to identify novel non-dopaminergic mechanisms as new therapeutic targets for Parkinson's disease (PD). Among these, the soluble guanylyl cyclase (sGC)-cGMP signaling cascade is emerging as a promising candidate
Publikováno v:
Experimental neurology. 219(1)
Currently existing behavioral measures for motor impairments in rodent models with bilateral dopamine depletion have demonstrated to be difficult to assess due to the degree of task complexity. There is clearly a need for a behavioral test that is si