Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daryl Subramaniam"'
Publikováno v:
Journal of Neurochemistry. 102:1276-1291
We have previously shown that statins reduce the production of amyloid-beta (Abeta) by both isoprenoid- and cholesterol-dependent mechanisms. These pathways contribute to the regulation of the dimerisation of BACE into its physiologically active form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2e0feea81b726ee1206393b7cf7457
https://doi.org/10.1111/j.1471-4159.2007.04619.x
https://doi.org/10.1111/j.1471-4159.2007.04619.x
We present the case of an 82-year-old Caucasian lady with a 16-day history of colicky lower abdominal pain and reduced appetite. When presenting to hospital she was haemodynamically stable with no fever. Examination revealed a soft but tender abdomen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00add9dc08a2e6a8d70d6067ce5095e5
https://europepmc.org/articles/PMC3604302/
https://europepmc.org/articles/PMC3604302/
Publikováno v:
Biochemical Society transactions. 35(Pt 3)
Statins inhibit the dimerization of β-secretase [BACE (β-site amyloid precursor protein-cleaving enzyme)] by inhibiting the lipidation of BACE and associated proteins. Our studies have demonstrated a clearly defined temporal sequence for these reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bfc6b83e70df244e2c88ebda19d22d
https://pubmed.ncbi.nlm.nih.gov/17511656
https://pubmed.ncbi.nlm.nih.gov/17511656
Publikováno v:
Case Reports. 2013:bcr2013201474-bcr2013201474
The development of Fournier's gangrene in an 80-year-old male patient with diabetes after a routine outpatient haemorrhoid banding procedure is described. Four days following the procedure, the patient noticed an increasing amount of pain and swellin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fdbcb1eab9b3a83ae89cb14d362c7c
https://doi.org/10.1136/bcr-2013-201474
https://doi.org/10.1136/bcr-2013-201474
Publikováno v:
International Journal of Surgery. 11:626
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fa7e0be92d89105ab6ce0319d4d780
https://doi.org/10.1016/j.ijsu.2013.06.211
https://doi.org/10.1016/j.ijsu.2013.06.211