Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Daryl R. Sauer"'
Publikováno v:
Journal of Flow Chemistry. 3:34-40
A continuous-flow microfluidic electrochemical device (Flux Module) has been designed and evaluated as a practical new laboratory tool to facilitate electrochemical synthetic transformations. Four- and six-electron benzylic oxidations are reported to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23f9cc9665ed0d0833353e15545241f
https://doi.org/10.1556/jfc-d-13-00002
https://doi.org/10.1556/jfc-d-13-00002
Publikováno v:
Tetrahedron Letters. 50:5145-5148
A ‘catch and release’ two-step one-pot protocol has been developed for the facile and practical synthesis of substituted guanidines from thioureas and various amines utilizing readily available brominated polystyrene resin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::075c385df9ad78b88563fad5fa867a52
https://doi.org/10.1016/j.tetlet.2009.06.113
https://doi.org/10.1016/j.tetlet.2009.06.113
Autor:
Jeffrey Y. Pan, Bruce Clapham, David M Dingle, David P Blanchard, Daryl R. Sauer, Melissa J. Michmerhuizen, Thomas A. Nemcek, Wilson Noel S
Publikováno v:
Journal of Combinatorial Chemistry. 10:88-93
This manuscript details the construction of a fully automated flow hydrogenation apparatus for use in high-throughput organic synthesis. The instrument comprises of a Bohdan robot platform coupled with a ThalesNano H-cube hydrogenator and a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460aa020e67597dcc1de17b61e0117bf
https://doi.org/10.1021/cc700178a
https://doi.org/10.1021/cc700178a
Publikováno v:
Tetrahedron Letters. 48:5181-5184
Acylsulfonamides can be rapidly and conveniently synthesized from a variety of carboxylic acids and sulfonamides utilizing the commercially available reagents, PS-DCC and DMAP under mild reaction conditions. DMAP can be efficiently scavenged by utili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609bcdc33860c272a7db0bcd88b7afed
https://doi.org/10.1016/j.tetlet.2007.05.158
https://doi.org/10.1016/j.tetlet.2007.05.158
Publikováno v:
Tetrahedron Letters. 48:2237-2240
Triazolopyridines can be rapidly and efficiently synthesized from a variety of carboxylic acids with 2-hydrazinopyridines in one simple step. The use of commercially available PS-PPh 3 resin combined with microwave heating delivered the product triaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8b123dbffce1b347403b332b8ad84a
https://doi.org/10.1016/j.tetlet.2007.02.004
https://doi.org/10.1016/j.tetlet.2007.02.004
Publikováno v:
Tetrahedron Letters. 47:4823-4826
Benzoxazoles or benzimidazoles can be rapidly and efficiently synthesized from a variety of carboxylic acids with 2-aminophenols or 1,2-phenylenediamines in one simple step, respectively. The use of commercially available PS-PPh3 resin combined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f5cd48f4f05dc2c2f3a93ae7bef8853
https://doi.org/10.1016/j.tetlet.2006.05.052
https://doi.org/10.1016/j.tetlet.2006.05.052
Publikováno v:
Tetrahedron Letters. 47:105-108
1,3,4-Oxadiazoles can be rapidly and efficiently synthesized from a variety of carboxylic acids and acid hydrazides in one simple step. The use of commercially available PS-PPh 3 resin combined with microwave heating delivered the product 1,3,4-oxadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0676f971ab4061e5ef840944ceec21
https://doi.org/10.1016/j.tetlet.2005.10.131
https://doi.org/10.1016/j.tetlet.2005.10.131
Publikováno v:
Organic Letters. 7:925-928
1,2,4-Oxadiazoles can be rapidly and efficiently synthesized from a variety of readily available carboxylic acids and amidoximes using either method A or method B. The use of commercially available polymer-supported reagents combined with microwave h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b805a24fffd80877498baa95ce57aa
https://doi.org/10.1021/ol050007r
https://doi.org/10.1021/ol050007r
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:1599-1602
Antibacterial SAR for a series of macrolides derived from erythromycin A that are potent LHRH antagonists was developed in an attempt to eliminate the antibiotic activities of these compounds. Increasing the size of the alkyl substituents on the deso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ed12e41e789e1d5cbef835cb9565e6
https://doi.org/10.1016/j.bmcl.2003.12.059
https://doi.org/10.1016/j.bmcl.2003.12.059
Autor:
Daryl R. Sauer, Jonathan Greer, Charles J. Nichols, Craig D. Wegner, Jason A. Segreti, Kurt M. Mohning, Fortuna Haviv, John T. Randolph, E N Bush, Philip L. Waid, Gilbert Diaz, Leslie M. Besecke, Gary Bammert
Publikováno v:
Journal of Medicinal Chemistry. 47:1085-1097
The design and synthesis of a series of 11,12-cyclic carbamate derivatives of 6-O-methylerythromycin A that are novel, nonpeptide LHRH antagonists, is described. The macrolide antagonist 1, discovered during a screen of our chemical repository, was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fabef2f09ac213c5e8373f774e466e4
https://doi.org/10.1021/jm030418i
https://doi.org/10.1021/jm030418i