Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daryl Dekarske"'
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: More than half of patients with Parkinson’s disease will experience psychosis symptoms in the form of hallucinations or delusions at some point over the course of their disease. These symptoms can significantly impact patients’ health
Externí odkaz:
https://doaj.org/article/3b0df1a440874b68a9dd8f87031e7f60
Publikováno v:
Geriatrics, Vol 6, Iss 2, p 61 (2021)
Dysphagia (difficulty swallowing) affects up to 13% of persons 65 years and older and 51% of older persons in nursing homes and can contribute to reduced adherence to oral medications. This was an exploratory, single-center, open-label, randomized, c
Externí odkaz:
https://doaj.org/article/56840379906e4e2ab3c011b06e1b0f80
Autor:
Mona Darwish, Bryan Dirks, Julie Passarell, David Jaworowicz, Sebastien Bihorel, Becky Howell, Joel Owen, Daryl DeKarske, Srdjan Stankovic
Publikováno v:
Clinical Pharmacology in Drug Development. 12:463-474
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2442a44ffb473c0319c0eaf6f2fccb41
https://doi.org/10.1002/cpdd.1232
https://doi.org/10.1002/cpdd.1232
Autor:
Mona, Darwish, Dragana, Bugarski-Kirola, Julie, Passarell, Joel, Owen, David, Jaworowicz, Daryl, DeKarske, Srdjan, Stankovic
Publikováno v:
Journal of Clinical Psychopharmacology. 42:544-551
Pimavanserin is a selective serotonin 5-HT 2A receptor inverse agonist/antagonist being investigated in patients with negative symptoms of schizophrenia. This analysis aimed to characterize exposure-response relationships of pimavanserin in this popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e33b838c84927aeebc2d66636279bb
https://doi.org/10.1097/jcp.0000000000001611
https://doi.org/10.1097/jcp.0000000000001611
Publikováno v:
Clinical Drug Investigation. 42:513-524
Trofinetide, a synthetic analog of tripeptide glycine-proline-glutamate, is an investigational agent for the treatment of Rett syndrome, a neurodevelopmental disorder with affected individuals requiring lifelong support. Food can affect the pharmacok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc2c5ad80550d72c18474a5ecacffe5
https://doi.org/10.1007/s40261-022-01156-4
https://doi.org/10.1007/s40261-022-01156-4
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5dc57245b02c5d856d3bb3fa0752f70
https://doi.org/10.1002/alz.057479
https://doi.org/10.1002/alz.057479
Autor:
Victor Abler, Marc Cantillon, Jason L. Aldred, Lori Jacobi, Gustavo Alva, James C. Norton, Daryl DeKarske, Rene Nunez, Bruce Coate
Publikováno v:
Journal of Parkinson's Disease
Background: Many patients with Parkinson’s disease (PD) experience depression. Objective: Evaluate pimavanserin treatment for depression in patients with PD. Methods: Pimavanserin was administered as monotherapy or adjunctive therapy to a selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bde8bb7f1da2492cfaadc2f244aabb1
https://pubmed.ncbi.nlm.nih.gov/32804101
https://pubmed.ncbi.nlm.nih.gov/32804101
Autor:
Marc Cantillon, Jason L. Aldred, James C. Norton, Michael T. Guskey, Bruce Coate, Gustavo Alva, Daryl DeKarske
Publikováno v:
CNS Spectrums. 25:301-301
Study Objectives:Depression occurs in ~50% of Parkinson’s disease (PD) patients, increases in severity and duration as the disease progresses, and is associated with increased morbidity. Improvement of depression in PD patients is correlated with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42fd9c26197311cd43c783f8b42e4a5a
https://doi.org/10.1017/s1092852920000747
https://doi.org/10.1017/s1092852920000747