Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Daryl A. Roston"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 26:725-738
Assay development, assay validation, and documentation are reported here for a single packed column pressurized fluid chromatographic/ultraviolet (UV) method that provides: (1) simultaneous detection and quantification for the chiral drug, the chiral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f12f885639690f4af6333082b1d037
https://doi.org/10.1016/s0731-7085(01)00441-1
https://doi.org/10.1016/s0731-7085(01)00441-1
Autor:
Jeffrey J. Sun, Daryl A. Roston
Publikováno v:
Journal of Chromatography A. 673:211-218
Matrix effects during standard addition analysis were studied through the determination of trace amounts of butyric acid (a reagent in the synthesis of an experimental drug substance and a residual component affecting the drug quality). By studying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e608da8cec65eec5b571536d4dbea045
https://doi.org/10.1016/0021-9673(94)85038-0
https://doi.org/10.1016/0021-9673(94)85038-0
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 11:293-300
The present study demonstrates the utility of a diversified analytical approach for the characterization and quantitative analysis for two polymorphs of a new anti-inflammatory agent, (+/-)-7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy-3,4-dihydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e421b4c66126f9227c7654436a2d5a
https://doi.org/10.1016/0731-7085(93)80020-2
https://doi.org/10.1016/0731-7085(93)80020-2
Autor:
Daryl A. Roston
Publikováno v:
Drug Development and Industrial Pharmacy. 18:245-255
An on-line SFE-SFC system was used to extract and chromatograph a synthetic prostaglandin from hydroxypropyl methylcellulose (HPMC), which is a widely used material in controlled-release drug formulations. The only sample preparation for the on-line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a093b9ae7d85dd14bd932d6f7cc3152d
https://doi.org/10.3109/03639049209043697
https://doi.org/10.3109/03639049209043697
Autor:
Rick R. Rhinebarger, Daryl A. Roston
Publikováno v:
Journal of Liquid Chromatography. 14:539-556
The present report describes development of a reversed-phase, ion-pairing, high-performance liquid chromatographic method with pulsed amperometric detection for analysis of a new aminosugar drug substance, N-butyldeoxynojirimycin, which has been iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba215963a710a6899fcaeeabed57c9f
https://doi.org/10.1080/01483919108049269
https://doi.org/10.1080/01483919108049269
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 26(3)
The current study assesses the effect of extending column length during gradient packed column sub/supercritical fluid chromatography (PCSFC) experiments on the detection of known and unknown impurities in a drug substance sample. Quantitative drug s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef17dcb123fc72de170d8a33782ebef
https://pubmed.ncbi.nlm.nih.gov/11489380
https://pubmed.ncbi.nlm.nih.gov/11489380
Autor:
Daryl A. Roston, Jeffrey J. Sun
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 15(4)
Supercritical fluid extraction (SFE) was evaluated as a sample preparation procedure for the recovery of experimental drugs from animal feed preparations that are generated during long-term toxicology studies. A commercially available supercritical f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25a12feb9aa8a18c3e80d38602460c3
https://pubmed.ncbi.nlm.nih.gov/8953489
https://pubmed.ncbi.nlm.nih.gov/8953489
Autor:
Daryl A. Roston, Peter T. Kissinger
Publikováno v:
Analytical Chemistry. 54:429-434
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c702552d13490bbd2262c4790562568
https://doi.org/10.1021/ac00240a019
https://doi.org/10.1021/ac00240a019
Publikováno v:
Talanta. 36:373-377
Conventional reversed-phase HPLC conditions have been optimized for resolution of a mixture containing prostaglandins PGE 1 , PGE 2 , PGF 1α , and PGF 2α . Electroactive derivative-forming reagents, such as p -nitrobenzyloxyamine, 2-bromo-2′-nitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0e2d874357e6b1e3cd00a63c7af011
https://doi.org/10.1016/0039-9140(89)80203-6
https://doi.org/10.1016/0039-9140(89)80203-6
Publikováno v:
Analytical Chemistry. 54:1417A-1434A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb3406e88d6f6261dcb56520d40f83e
https://doi.org/10.1021/ac00250a003
https://doi.org/10.1021/ac00250a003