Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Darya Tsibulskaya"'
Autor:
Eldar Yagmurov, Darya Tsibulskaya, Alexey Livenskyi, Marina Serebryakova, Yury I. Wolf, Sergei Borukhov, Konstantin Severinov, Svetlana Dubiley
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The Escherichia coli microcin C (McC) and related compounds are potent Trojan horse peptide-nucleotide antibiotics. The peptide part facilitates transport into sensitive cells. Inside the cell, the peptide part is degraded by nonspecific pep
Externí odkaz:
https://doaj.org/article/b80e8b2de51b4e6eac6f5593db304134
Autor:
Inna Zukher, Michael Pavlov, Darya Tsibulskaya, Alexey Kulikovsky, Tatyana Zyubko, Dmitry Bikmetov, Marina Serebryakova, Satish K. Nair, Måns Ehrenberg, Svetlana Dubiley, Konstantin Severinov
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Microcin C (McC) is a peptide adenylate antibiotic produced by Escherichiacoli cells bearing a plasmid-borne mcc gene cluster. Most MccA precursors, encoded by validated mcc operons from diverse bacteria, are 7 amino acids long, but the sign
Externí odkaz:
https://doaj.org/article/1320d8f1afa64361aa8de0fbe621008b
Autor:
Alexey Kulikovsky, Darya Tsibulskaya, Måns Ehrenberg, Dmitry Bikmetov, Svetlana Dubiley, Inna Zukher, Konstantin Severinov, Michael Y. Pavlov, Tatyana Zyubko, Marina V. Serebryakova, Satish K. Nair
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00768-19 (2019)
mBio, Vol 10, Iss 2, p e00768-19 (2019)
Microcin C (McC) is a peptide adenylate antibiotic produced by Escherichiacoli cells bearing a plasmid-borne mcc gene cluster. Most MccA precursors, encoded by validated mcc operons from diverse bacteria, are 7 amino acids long, but the significance
Autor:
Darya Tsibulskaya, Svetlana Dubiley, Julia Piskunova, Olga Mokina, Konstantin Severinov, Marina V. Serebryakova, Alexey Kulikovsky
Publikováno v:
Journal of the American Chemical Society. 139(45)
Microcin C is a heptapeptide-adenylate antibiotic produced by some strains of Escherichia coli. Its peptide part is responsible for facilitated transport inside sensitive cells where it is proteolyzed with release of a toxic warhead-a nonhydrolyzable
Autor:
Arthur Van Aerschot, Darya Tsibulskaya, Alexey Kulikovsky, Svetlana Dubiley, Olga Mokina, Manesh Nautiyal, Marina V. Serebryakova, Konstantin Severinov
Publikováno v:
Journal of the American Chemical Society
Microcin C and related antibiotics are Trojan-horse peptide-adenylates. The peptide part is responsible for facilitated transport inside the sensitive cell, where it gets processed to release a toxic warhead—a nonhydrolyzable aspartyl-adenylate, wh
Autor:
Alexey Kulikovsky, Konstantin Severinov, Marina V. Serebryakova, Olga Bantysh, Inna Zukher, Svetlana Dubiley, Darya Tsibulskaya
Publikováno v:
Journal of bacteriology. 197(19)
Escherichia coli microcin C (McC) consists of a ribosomally synthesized heptapeptide attached to a modified adenosine. McC is actively taken up by sensitive Escherichia coli strains through the YejABEF transporter. Inside the cell, McC is processed b