Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Darya Mitrofanova"'
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2158 (2019)
Cells of unicellular and multicellular eukaryotes can respond to certain environmental cues by arresting the cell cycle and entering a reversible state of quiescence. Quiescent cells do not divide, but can re-enter the cell cycle and resume prolifera
Externí odkaz:
https://doaj.org/article/8dea9fee11414ffb897cfff963ca26b6
Autor:
Karamat Mohammad, Paméla Dakik, Younes Medkour, Mélissa McAuley, Darya Mitrofanova, Vladimir I. Titorenko
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 860 (2018)
The concentrations of some key metabolic intermediates play essential roles in regulating the longevity of the chronologically aging yeast Saccharomyces cerevisiae. These key metabolites are detected by certain ligand-specific protein sensors that re
Externí odkaz:
https://doaj.org/article/2dcc5acbd6f040048232d6fd5e26e85d
Autor:
Veronika Svistkova, Paola Escudero, Jennifer Anne Baratang Junio, Karamat Mohammad, Monica Enith Lozano Rodriguez, Vladimir I. Titorenko, Darya Mitrofanova, Younes Medkour, Hana Maalaoui, Tarek Taifour, Anthony Arlia-Ciommo, Sahar Soodbakhsh, Éric Simard, Pamela Dakik, Fani-Fay Goltsios
Publikováno v:
Oncotarget
We have recently found that PE21, an extract from the white willow Salix alba, slows chronological aging and prolongs longevity of the yeast Saccharomyces cerevisiae more efficiently than any of the previously known pharmacological interventions. Her
Autor:
Jennifer Anne Baratang Junio, Vladimir I. Titorenko, Tarek Taifour, Anthony Arlia-Ciommo, Darya Mitrofanova, Tala Tafakori, Vicky Lutchman, Younes Medkour, Pamela Dakik, Monica Enith Lozano Rodriguez, Eugenie Samson, Belise Rukundo, Éric Simard
Publikováno v:
Oncotarget
In a quest for previously unknown geroprotective natural chemicals, we used a robust cell viability assay to search for commercially available plant extracts that can substantially prolong the chronological lifespan of budding yeast. Many of these pl
Autor:
Darya Mitrofanova, Mélissa McAuley, Vladimir I. Titorenko, Younes Medkour, Pamela Dakik, Karamat Mohammad
Publikováno v:
Frontiers in Bioscience. 23:1166-1194
Emergent evidence indicates that certain aspects of lipid synthesis, degradation and interorganellar transport play essential roles in modulating the pace of cellular aging in the budding yeast Saccharomyces cerevisiae. The molecular mechanisms under
Autor:
Darya Mitrofanova, Younes Medkour, Mélissa McAuley, Vladimir I. Titorenko, Karamat Mohammad, Pamela Dakik
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
The functional state of mitochondria is vital to cellular and organismal aging in eukaryotes across phyla. Studies in the yeastSaccharomyces cerevisiaehave provided evidence that age-related changes in some aspects of mitochondrial functionality can
Autor:
Éric Simard, Jennifer Anne Baratang Junio, Darya Mitrofanova, Mélissa McAuley, Berly Cortes, Vicky Lutchman, Marisa Chancharoen, Vladimir I. Titorenko, Monica Enith Lozano Rodriguez, Pamela Dakik
Publikováno v:
Oncotarget
We have recently discovered six plant extracts that delay yeast chronological aging. Most of them affect different nodes, edges and modules of an evolutionarily conserved network of longevity regulation that integrates certain signaling pathways and
Autor:
Mélissa McAuley, Karamat Mohammad, Younes Medkour, Vladimir I. Titorenko, Pamela Dakik, Darya Mitrofanova
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 860 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The concentrations of some key metabolic intermediates play essential roles in regulating the longevity of the chronologically aging yeast Saccharomyces cerevisiae. These key metabolites are detected by certain ligand-specific protein sensors that re
Autor:
Mélissa McAuley, Pamela Dakik, Vladimir I. Titorenko, Darya Mitrofanova, Karamat Mohammad, Younes Medkour
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
A disturbed homeostasis of cellular lipids and the resulting lipotoxicity are considered to be key contributors to many human pathologies, including obesity, metabolic syndrome, type 2 diabetes, cardiovascular diseases, and cancer. The yeast Saccharo