Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Darya, Kiryushko"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-7 (2023)
Abstract The ability to image cell chemistry at the nanoscale is key for understanding cell biology, but many optical microscopies are restricted by the ~(200–250)nm diffraction limit. Electron microscopy and super-resolution fluorescence technique
Externí odkaz:
https://doaj.org/article/968092649e6b4c4192d321acc9cc8515
Autor:
Vincenzo Mangini, Claire M. Cobley, Fabio Benfenati, Roland A. Fleck, Darya Kiryushko, Roberto Dr. Fiammengo, Pedro Machado, Silvio Sacchetti, Pierluigi Valente, Joachim P. Spatz, Alexandra E. Porter
Publikováno v:
ACS Nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51203ad24835a78037950999c3e8d391
https://doi.org/10.1021/acsnano.1c05607
https://doi.org/10.1021/acsnano.1c05607
Autor:
Corinne Morfill, Stanislava Pankratova, Pedro Machado, Nathalie K. Fernando, Anna Regoutz, Federica Talamona, Alessandra Pinna, Michal Klosowski, Robert J. Wilkinson, Roland A. Fleck, Fang Xie, Alexandra E. Porter, Darya Kiryushko
Publikováno v:
Morfill, C, Pankratova, S, Machado, P, Fernando, N K, Regoutz, A, Talamona, F, Pinna, A, Klosowski, M, Wilkinson, R J, Fleck, R A, Xie, F, Porter, A E & Kiryushko, D 2022, ' Nanostars Carrying Multifunctional Neurotrophic Dendrimers Protect Neurons in Preclinical In Vitro Models of Neurodegenerative Disorders ', ACS applied materials & interfaces, vol. 14, no. 42, pp. 47445–47460 . https://doi.org/10.1021/acsami.2c14220
A challenge in neurology is the lack of efficient brain-penetrable neuroprotectants targeting multiple disease mechanisms. Plasmonic gold nanostars are promising candidates to deliver standard-of-care drugs inside the brain but have not been trialed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a434b7523f65fd5823f1c295e02141
https://pubmed.ncbi.nlm.nih.gov/36218307
https://pubmed.ncbi.nlm.nih.gov/36218307
Autor:
Mihai Moldovan, Volodymyr Pinchenko, Oksana Dmytriyeva, Stanislava Pankratova, Kåre Fugleholm, Jorg Klingelhofer, Elisabeth Bock, Vladimir Berezin, Christian Krarup, Darya Kiryushko
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 43-53 (2013)
Abstract We recently found that S100A4, a member of the multifunctional S100 protein family, protects neurons in the injured brain and identified two sequence motifs in S100A4 mediating its neurotrophic effect. Synthetic peptides encompassing these m
Externí odkaz:
https://doaj.org/article/242884535b06493ba6c278273d8f8129
Publikováno v:
ACS Applied Materials & Interfaces. 11:36307-36315
Molecular mobility in neuronal plasma membranes is a crucial factor in brain function. Microscopic viscosity is an important parameter that determines molecular mobility. This study presents the first direct measurements of the microviscosity of plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bab933c981a150e88d1a9db68d4f2f
https://doi.org/10.1021/acsami.9b10426
https://doi.org/10.1021/acsami.9b10426
Autor:
R. Charles Coombes, Ernesto Yagüe, Carlo Palmieri, Darya Kiryushko, Erik R Taylor, Ioannis G Theodorou, Michał M. Kłosowski, Mary P. Ryan, Thisa Niriella, Pakatip Ruenraroengsak, Fang Xie, Alexandra E. Porter
Publikováno v:
Nanoscale. 11:12858-12870
There is a need for novel strategies to treat aggressive breast cancer subtypes and overcome drug resistance. ZnO nanoparticles (NPs) have potential in cancer therapy due to their ability to potently and selectively induce cancer cell apoptosis. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e628cb6481194c431aaf03c78f81ff
https://doi.org/10.1039/c9nr01277j
https://doi.org/10.1039/c9nr01277j
Autor:
Pierluigi, Valente, Darya, Kiryushko, Silvio, Sacchetti, Pedro, Machado, Claire M, Cobley, Vincenzo, Mangini, Alexandra E, Porter, Joachim P, Spatz, Roland A, Fleck, Fabio, Benfenati, Roberto, Fiammengo
Publikováno v:
ACS nano. 14(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6daf0c23ae36056d75cadefc328b4e60
https://pubmed.ncbi.nlm.nih.gov/32510204
https://pubmed.ncbi.nlm.nih.gov/32510204
Autor:
Vincenzo Mangini, Fabio Benfenati, Joachim P. Spatz, Silvio Sacchetti, Roland A. Fleck, Roberto Fiammengo, Darya Kiryushko, Alexandra E. Porter, Pedro Machado, Claire M. Cobley, Pierluigi Valente
Publikováno v:
ACS Nano
N-methyl-d-aspartate receptors (NMDARs) are ionotropic glutamate receptors controlling fundamental physiological processes in the central nervous system, such as learning and memory. Excessive activation of NMDARs causes excitotoxicity and results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06759c8f4cbab3a6fae28d4a9450a22d
https://hdl.handle.net/11562/1024503
https://hdl.handle.net/11562/1024503
Autor:
Seigo Masuda, Sheng Hu, Daniel Gonzalez-Carter, Angela E. Goode, Darya Kiryushko, Rosalia Lopes-Rodrigues, David T. Dexter, Alexandra E. Porter, Milo S. P. Shaffer
Nanoparticles capable of penetrating the blood-brain barrier (BBB) will greatly advance the delivery of therapies against brain disorders. Carbon nanotubes hold great potential as delivery vehicles due to their high aspect-ratio and cell-penetrating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccfd82369ae163bc494f5c674adf038
http://hdl.handle.net/10044/1/74557
http://hdl.handle.net/10044/1/74557
Amyloid deposits of aggregated beta-amyloid Aβ(1-42) peptides are a pathological hallmark of Alzheimer's disease. Aβ(1-42) aggregates are known to induce biophysical alterations in cells, including disruption of plasma membranes. We investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecbea5b961c4c0b72a31971bee3dcfe
http://hdl.handle.net/10044/1/65822
http://hdl.handle.net/10044/1/65822