Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Darwin S. Dichmann"'
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 527-536 (2015)
Alternative splicing is pervasive in vertebrates, yet little is known about most isoforms or their regulation. transformer-2b (tra2b) encodes a splicing regulator whose endogenous function is poorly understood. Tra2b knockdown in Xenopus results in e
Externí odkaz:
https://doaj.org/article/4e917aed01e146c7bb3430b8cc021523
Publikováno v:
Development
The FET family of atypical RNA-binding proteins includes Fused in sarcoma (Fus), Ewings sarcoma (EWS), and the TATA-binding protein-associate factor 15 (TAF15). All FET family members are highly conserved from fish to mammals, suggesting an independe
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 1
Significance The majority of transcription generates noncoding RNAs, most of which are uncharacterized. Using RNA-seq on cultured mouse sclerotome, we identified PEAT , a long-noncoding RNA (lncRNA) adjacent to a key regulator of sclerotome, Pax1 . W
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 527-536 (2015)
Dichmann, Darwin S.; Walentek, Peter; & Harland, Richard. M.(2015). The Alternative Splicing Regulator Tra2b Is Required for Somitogenesis and Regulates Splicing of an Inhibitory Wnt11b Isoform. Cell Reports, 10(4), 527-536. doi: 10.1016/j.celrep.2014.12.046. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/7111g1h4
Dichmann, Darwin S.; Walentek, Peter; & Harland, Richard. M.(2015). The Alternative Splicing Regulator Tra2b Is Required for Somitogenesis and Regulates Splicing of an Inhibitory Wnt11b Isoform. Cell Reports, 10(4), 527-536. doi: 10.1016/j.celrep.2014.12.046. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/7111g1h4
SummaryAlternative splicing is pervasive in vertebrates, yet little is known about most isoforms or their regulation. transformer-2b (tra2b) encodes a splicing regulator whose endogenous function is poorly understood. Tra2b knockdown in Xenopus resul
Autor:
Shuji Takahashi, Yutaka Suzuki, Douglas W. Houston, Christian D. Haudenschild, Tsutomu Kinoshita, Darwin S. Dichmann, Shuuji Mawaribuchi, Masanori Taira, Jane Grimwood, Martin F. Flajnik, Yumi Izutsu, Tatsuo Michiue, Michihiko Ito, Yoko Kuroki, Yuzuru Ito, Yuko Ohta, Oleg Simakov, Ila van Kruijsbergen, Taejoon Kwon, Shengquiang Shu, Jacob O. Kitzman, Edward M. Marcotte, Adam M. Session, Yuuri Yasuoka, Sahar V. Mozaffari, Jonathan C. Stites, Jay Shendure, Minoru Watanabe, Joseph W. Carlson, Rebecca Heald, Nicholas H. Putnam, Akimasa Fukui, John B. Wallingford, Aaron M. Zorn, Kevin A. Burns, Atsushi Suzuki, Sven Heinz, Jarrod Chapman, Therese Mitros, Hajime Ogino, Georgios Georgiou, Makoto Asashima, Kamran Karimi, Uffe Hellsten, Jeremy Schmutz, Daniel S. Rokhsar, Joshua D. Fortriede, Yoshinobu Uno, Vaneet Lotay, Jerry Jenkins, Simon J. van Heeringen, Akira Hikosaka, Toshiaki Tanaka, Atsushi Toyoda, Yoshikazu Haramoto, Sarita S. Paranjpe, Chiyo Takagi, Yoichi Matsuda, Takuya Nakayama, Takamasa S. Yamamoto, Ryan Lister, Asao Fujiyama, Richard M. Harland, Ian K. Quigley, Kelly E. Miller, Louis DuPasquier, Peter D. Vize, Gert Jan C. Veenstra, Mariko Kondo, Ozren Bogdanovic, Haruki Ochi, Jessica B. Lyons, Jacques Robert, Naoto Ueno
Publikováno v:
Nature, vol 538, iss 7625
Nature, 538, 336-362
Nature, 538, pp. 336-362
Nature, 538, 336-362
Nature, 538, pp. 336-362
To explore the origins and consequences of tetraploidy in the African clawed frog, we sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis genome. We characterize the allotetraploid origin of X. laevis by partition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb634b9e56d258b46c4fef0a637602ed
https://escholarship.org/uc/item/8h02q9hf
https://escholarship.org/uc/item/8h02q9hf
Autor:
Richard M. Harland, Darwin S. Dichmann
Publikováno v:
Genes & Development. 26:1351-1363
Here we investigated the function of the atypical RNA-binding protein fus/TLS (fused in sarcoma/translocated in sarcoma) during early frog development. We found that fus is necessary for proper mRNA splicing of a set of developmental regulatory genes
Publikováno v:
Developmental Dynamics. 235:3016-3025
Here, we examine the role of GDF11 in pancreatic development. Using in situ hybridization and reverse transcriptase-polymerase chain reaction analyses, we show that Gdf11 transcripts are expressed in embryonic pancreas epithelium before the secondary
Publikováno v:
Developmental Dynamics. 226:663-674
We have performed a high-capacity, semiquantitative, reverse transcriptase-polymerase chain reaction screen for expression of fibroblast growth factor (FGF) and transforming growth factor beta (TGFbeta) family genes as well as their cognate receptors
Autor:
B. Tang, Lingguang Cui, Maureen J. Charron, John Rømer, H. Huang, Jens J. Holst, Peter B. Johansen, Richard W. Gelling, Erica Nishimura, Christian Fledelius, Xueliang Du, Darwin S. Dichmann, Linda A. Jelicks, Luciano Rossetti, Palle Serup, Silvana Obici
Publikováno v:
Proceedings of the National Academy of Sciences. 100:1438-1443
Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic α cells in response to low blood glucose. To examine the role of glucagon in glucose homeostasis, mice were generated with a null mutation of the glucagon receptor (Gcg
Autor:
Richard M. Harland, Darwin S. Dichmann
Publikováno v:
Developmental biology. 349(2)
Neuronal subtypes originate from an undifferentiated neural epithelium that is progressively divided into progenitor domains by homeodomain transcription factors such as members of the Nkx family. Here we report the functional analysis of Nkx6.1 and