Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Darwin D'Souza"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 148-148 (2024)
OBJECTIVES/GOALS: The major obstacle to an effective cure or remission for HIV infection is the integration of HIV into the genome of long-lived resting cells which constitute the so-called viral reservoir. With this study we want to elucidate the ch
Externí odkaz:
https://doaj.org/article/4f4cdb0b8ff0459d94a197abe7f58b48
Autor:
Michael Naidoo, Leanne Jones, Benjamin Conboy, Wael Hamarneh, Darwin D’Souza, Karen Anthony, Lee R. Machado
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Alterations in the expression of the Duchenne muscular dystrophy (DMD) gene have been associated with the development, progression and survival outcomes of numerous cancers including tumours of the central nervous system. We undertook a deta
Externí odkaz:
https://doaj.org/article/c7cc1985e9d4490d99f8da0a5b4c4756
Autor:
Charles E. Bullerwell, Philippe Pierre Robichaud, Pierre M. L. Deprez, Andrew P. Joy, Gabriel Wajnberg, Darwin D’Souza, Simi Chacko, Sébastien Fournier, Nicolas Crapoulet, David A. Barnett, Stephen M. Lewis, Rodney J. Ouellette
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract PAX5 and EBF1 work synergistically to regulate genes that are involved in B lymphocyte differentiation. We used the KIS-1 diffuse large B cell lymphoma cell line, which is reported to have elevated levels of PAX5 expression, to investigate t
Externí odkaz:
https://doaj.org/article/5b11cbd215904b91952bccb6c01327a7
Autor:
Matthew D. Park, Ivan Reyes-Torres, Jessica LeBerichel, Pauline Hamon, Nelson M. LaMarche, Samarth Hegde, Meriem Belabed, Leanna Troncoso, John A. Grout, Assaf Magen, Etienne Humblin, Achuth Nair, Martina Molgora, Jinchao Hou, Jenna H. Newman, Adam M. Farkas, Andrew M. Leader, Travis Dawson, Darwin D’Souza, Steven Hamel, Alfonso Rodriguez Sanchez-Paulete, Barbara Maier, Nina Bhardwaj, Jerome C. Martin, Alice O. Kamphorst, Ephraim Kenigsberg, Maria Casanova-Acebes, Amir Horowitz, Brian D. Brown, Lucas Ferrari De Andrade, Marco Colonna, Thomas U. Marron, Miriam Merad
Publikováno v:
Nature Immunology. 24:792-801
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03bc3b9e8d3d3b64cd6944d3408171bd
https://doi.org/10.1038/s41590-023-01475-4
https://doi.org/10.1038/s41590-023-01475-4
Autor:
Lijun Yao, Reyka G. Jayasinghe, Brian H. Lee, Swati S. Bhasin, William Pilcher, Deon Bryant Doxie, Edgar Gonzalez-Kozlova, Surendra Dasari, Mark A. Fiala, Yered Pita-Juarez, Michael Strausbauch, Geoffrey Kelly, Beena E. Thomas, Shaji K. Kumar, Hearn Jay Cho, Emilie Anderson, Michael C. Wendl, Travis Dawson, Darwin D'souza, Stephen T. Oh, Giulia Cheloni, Ying Li, John F. DiPersio, Adeeb H. Rahman, Kavita M. Dhodapkar, Seunghee Kim-Schulze, Ravi Vij, Ioannis S. Vlachos, Shaadi Mehr, Mark Hamilton, Daniel Auclair, Taxiarchis Kourelis, David Avigan, Madhav V. Dhodapkar, Sacha Gnjatic, Manoj K. Bhasin, Li Ding
Publikováno v:
Cancer Research Communications. 2:1255-1265
As part of the Multiple Myeloma Research Foundation (MMRF) immune atlas pilot project, we compared immune cells of multiple myeloma bone marrow samples from 18 patients assessed by single-cell RNA sequencing (scRNA-seq), mass cytometry (CyTOF), and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae1595f9d5482def5649d82d765b7f2
https://doi.org/10.1158/2767-9764.crc-22-0022
https://doi.org/10.1158/2767-9764.crc-22-0022
Autor:
Li Ding, Manoj K. Bhasin, Sacha Gnjatic, Madhav V. Dhodapkar, David Avigan, Taxiarchis Kourelis, Daniel Auclair, Mark Hamilton, Shaadi Mehr, Ioannis S. Vlachos, Ravi Vij, Seunghee Kim-Schulze, Kavita M. Dhodapkar, Adeeb H. Rahman, John F. DiPersio, Ying Li, Giulia Cheloni, Stephen T. Oh, Darwin D'souza, Travis Dawson, Michael C. Wendl, Emilie Anderson, Hearn Jay Cho, Shaji K. Kumar, Beena E. Thomas, Geoffrey Kelly, Michael Strausbauch, Yered Pita-Juarez, Mark A. Fiala, Surendra Dasari, Edgar Gonzalez-Kozlova, Deon Bryant Doxie, William Pilcher, Swati S. Bhasin, Brian H. Lee, Reyka G. Jayasinghe, Lijun Yao
Expression of cell type markers in CITE-seq and comparison of cell subset abundance between technical replicates and across different centers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b4d97031332b88d668c344989ef6b4
https://doi.org/10.1158/2767-9764.22545047.v1
https://doi.org/10.1158/2767-9764.22545047.v1
Autor:
Li Ding, Manoj K. Bhasin, Sacha Gnjatic, Madhav V. Dhodapkar, David Avigan, Taxiarchis Kourelis, Daniel Auclair, Mark Hamilton, Shaadi Mehr, Ioannis S. Vlachos, Ravi Vij, Seunghee Kim-Schulze, Kavita M. Dhodapkar, Adeeb H. Rahman, John F. DiPersio, Ying Li, Giulia Cheloni, Stephen T. Oh, Darwin D'souza, Travis Dawson, Michael C. Wendl, Emilie Anderson, Hearn Jay Cho, Shaji K. Kumar, Beena E. Thomas, Geoffrey Kelly, Michael Strausbauch, Yered Pita-Juarez, Mark A. Fiala, Surendra Dasari, Edgar Gonzalez-Kozlova, Deon Bryant Doxie, William Pilcher, Swati S. Bhasin, Brian H. Lee, Reyka G. Jayasinghe, Lijun Yao
supplementary table 1 shows cell type annotation markers, clinical information of patients, cross-technique comparison of cell subset abundance and expression of cell type marker genes in CITE-seq and CyTOF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a43147e97357ca395db0c3f061a35f8
https://doi.org/10.1158/2767-9764.22545041
https://doi.org/10.1158/2767-9764.22545041
Autor:
Li Ding, Manoj K. Bhasin, Sacha Gnjatic, Madhav V. Dhodapkar, David Avigan, Taxiarchis Kourelis, Daniel Auclair, Mark Hamilton, Shaadi Mehr, Ioannis S. Vlachos, Ravi Vij, Seunghee Kim-Schulze, Kavita M. Dhodapkar, Adeeb H. Rahman, John F. DiPersio, Ying Li, Giulia Cheloni, Stephen T. Oh, Darwin D'souza, Travis Dawson, Michael C. Wendl, Emilie Anderson, Hearn Jay Cho, Shaji K. Kumar, Beena E. Thomas, Geoffrey Kelly, Michael Strausbauch, Yered Pita-Juarez, Mark A. Fiala, Surendra Dasari, Edgar Gonzalez-Kozlova, Deon Bryant Doxie, William Pilcher, Swati S. Bhasin, Brian H. Lee, Reyka G. Jayasinghe, Lijun Yao
As part of the Multiple Myeloma Research Foundation (MMRF) immune atlas pilot project, we compared immune cells of multiple myeloma bone marrow samples from 18 patients assessed by single-cell RNA sequencing (scRNA-seq), mass cytometry (CyTOF), and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbd16971b30f00c19dbfb31fe88bcda
https://doi.org/10.1158/2767-9764.c.6550841
https://doi.org/10.1158/2767-9764.c.6550841
Autor:
Assaf Magen, Pauline Hamon, Nathalie Fiaschi, Leanna Troncoso, Etienne Humblin, Darwin D’souza, Travis Dawson, Matthew D. Park, Joel Kim, Steven Hamel, Mark Buckup, Christie Chang, Alexandra Tabachnikova, Hara Schwartz, Nausicaa Malissen, Yonit Lavin, Alessandra Soares-Schanoski, Bruno Giotti, Samarth Hegde, Raphaël Mattiuz, Clotilde Hennequin, Jessica Le Berichel, Zhen Zhao, Stephen Ward, Isabel Fiel, Colles Price, Nicolas Fernandez, Jiang He, Baijun Kou, Michael Dobosz, Lianjie Li, Christina Adler, Min Ni, Yi Wei, Wei Wang, Namita T. Gupta, Kunal Kundu, Kamil Cygan, Raquel P. Deering, Alex Tsankov, Seunghee Kim-Schulze, Sacha Gnjatic, Ephraim Kenigsberg, Myron Schwartz, Thomas U. Marron, Gavin Thurston, Alice O. Kamphorst, Miriam Merad
Here, we leveraged a large neoadjuvant PD-1 blockade trial in patients with hepatocellular carcinoma (HCC) to search for correlates of response to immune checkpoint blockade (ICB) within T cell-rich tumors. We show that ICB response correlated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04351ccef56bbab01aa40ecee8e4b71c
https://doi.org/10.1101/2022.06.22.497216
https://doi.org/10.1101/2022.06.22.497216
Autor:
Andrew P. Joy, Rodney J. Ouellette, David Barnett, Charles E. Bullerwell, Philippe Pierre Robichaud, Pierre M. L. Deprez, Gabriel Wajnberg, Darwin D’Souza, Simi Chacko, Stephen M. Lewis, Stéphanie Fournier, Nicolas Crapoulet
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
PAX5 and EBF1 work synergistically to regulate genes that are involved in B lymphocyte differentiation. We used the KIS-1 diffuse large B cell lymphoma cell line, which is reported to have elevated levels of PAX5 expression, to investigate the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e325414fdc3a58bc7f782e3fce9203
https://doi.org/10.1038/s41598-021-81000-5
https://doi.org/10.1038/s41598-021-81000-5