Leveraging Alumina-Templated

Autor: Darveau, Patrick

The work disclosed in this dissertation outlines a newly discovered acidic alumina-mediated orthoallylation of unprotected phenols and the application of this method to the synthesis of prenylated phenolic natural products including dorsmanin A and h

Externí odkaz: http://hdl.handle.net/11375/29239

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QSAR models reveal new EPAC-selective allosteric modulators.

Autor: Mohamed H; Department of Chemistry and Chemical Biology, McMaster University, Hamilton Ontario L8S 4L8 Canada melacin@mcmaster.ca., Shao H; Department of Chemistry and Chemical Biology, McMaster University, Hamilton Ontario L8S 4L8 Canada melacin@mcmaster.ca., Akimoto M; Department of Chemistry and Chemical Biology, McMaster University, Hamilton Ontario L8S 4L8 Canada melacin@mcmaster.ca., Darveau P; Department of Chemistry and Chemical Biology, McMaster University, Hamilton Ontario L8S 4L8 Canada melacin@mcmaster.ca., MacKinnon MR; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton Ontario L8S 4L8 Canada., Magolan J; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton Ontario L8S 4L8 Canada., Melacini G; Department of Chemistry and Chemical Biology, McMaster University, Hamilton Ontario L8S 4L8 Canada melacin@mcmaster.ca.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton Ontario L8S 4L8 Canada.

Publikováno v: RSC chemical biology [RSC Chem Biol] 2022 Aug 03; Vol. 3 (10), pp. 1230-1239. Date of Electronic Publication: 2022 Aug 03 (Print Publication: 2022).