Indole-3-Carbinol: Occurrence, Health-Beneficial Properties, and Cellular/Molecular Mechanisms

Autor: Darshika Amarakoon, Wu-Joo Lee, Gillian Tamia, Seong-Ho Lee

Publikováno v: Annual Review of Food Science and Technology. 14:347-366

Indole-3-carbinol (I3C) is a bioactive phytochemical abundant in cruciferous vegetables. One of its main in vivo metabolites is 3,3′-diindolylmethane (DIM), formed by the condensation of two molecules of I3C. Both I3C and DIM alter multiple signali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c710d40bfad8a31467d18c019caaba9
https://doi.org/10.1146/annurev-food-060721-025531

A mechanistic review: potential chronic disease‐preventive properties of sorghum

Autor: Seong-Ho Lee, Dmitriy Smolensky, Wu-Joo Lee, Zhiyuan Lou, Darshika Amarakoon

Publikováno v: Journal of the Science of Food and Agriculture. 101:2641-2649

Sorghum is one of the most widely cultivated crops, and is used in foods, domestic animal feedstuffs, alcohol production, and biofuels. Recently, many research groups have demonstrated that sorghum contains various components that are strongly associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3d4883e1b808957489285972bf27e1
https://doi.org/10.1002/jsfa.10933

Polyphenol Containing Sorghum Brans Exhibit an Anti-Cancer Effect in Apc Min/+ Mice Treated with Dextran Sodium Sulfate

Autor: Ramasamy Perumal, Darshika Amarakoon, Hee-Seop Lee, Jihye Lee, Dmitriy Smolensky, Seong-Ho Lee, Zhiyuan Lou, Leela E. Noronha, Thomas J. Herald

Publikováno v: International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8286
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8286, p 8286 (2021)

Colon cancer (CC) is considered a high-risk cancer in developed countries. Its etiology is correlated with a high consumption of red meat and low consumption of plant-based foods, including whole grains. Sorghum bran is rich in polyphenols. This stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92ea106e7bf9f9f04e19549b874001f

Adverse effect of polystyrene microplastics (PS-MPs) on tube formation and viability of human umbilical vein endothelial cells

Autor: Cheng-i Wei, Dmitriy Smolensky, Seong-Ho Lee, Kyu Yong Choi, Hee-Seop Lee, Darshika Amarakoon

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 154

Environmental contamination by microplastics (MPs) is an emerging concern in recent years due to associated adverse impacts of MPs on potential human health problems. Endothelial dysfunction is a condition in which the endothelial layer fails to form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d01e9d0c6bc49fb3598641a62a183a
https://pubmed.ncbi.nlm.nih.gov/34157338

Genetic and environmental variation of seed iron and food matrix factors of North-Dakota-grown field peas (Pisum sativum L.)

Autor: Darshika Amarakoon, Debjyoti Sen Gupta, Kevin E. McPhee, Pushparajah Thavarajah, Thomas M. DeSutter, Dil Thavarajah

Publikováno v: Journal of Food Composition and Analysis. 37:67-74

Iron (Fe) biofortification of staple food crops is carried out through genetic selection and breeding. This study determined the genetic and environmental variation of total seed Fe concentration and food matrix factors (carotenoids, kestose, phytic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::943ebbf114b0b3ff0d5064e6b26579cd
https://doi.org/10.1016/j.jfca.2014.09.001