ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae .

Autor: Davies DT; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Leiris S; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Sprynski N; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Castandet J; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Lozano C; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Bousquet J; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Zalacain M; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Vasa S; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Dasari PK; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Pattipati R; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Vempala N; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Gujjewar S; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Godi S; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Jallala R; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Sathyap RR; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Darshanoju NA; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Ravu VR; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Juventhala RR; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Pottabathini N; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Sharma S; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Pothukanuri S; Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India., Holden K; Evotec (U.K.) Ltd., Block 23, Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K., Warn P; Evotec (U.K.) Ltd., Block 23, Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K., Marcoccia F; Dipartimento di Biotecnologie Mediche, University of Siena, Viale Bracci 16, Siena, 53100, Italy., Benvenuti M; Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, Via Aldo Moro 2, Siena, 53100, Italy., Pozzi C; Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, Via Aldo Moro 2, Siena, 53100, Italy., Mangani S; Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, Via Aldo Moro 2, Siena, 53100, Italy., Docquier JD; Dipartimento di Biotecnologie Mediche, University of Siena, Viale Bracci 16, Siena, 53100, Italy., Lemonnier M; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France., Everett M; Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2020 Sep 11; Vol. 6 (9), pp. 2419-2430. Date of Electronic Publication: 2020 Aug 20.