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pro vyhledávání: '"Darshana Zhaveri"'
Autor:
William Markland, Ernst ter Haar, Darshana Zhaveri, Guy W. Bemis, Thomas Hoock, Martin Connors, Francesco G. Salituro, Shawn D. Britt, Cochran John E, Suganthini Nanthakumar, Edmund Harrington, Jian Wang, Luc J. Farmer, Paul Taslimi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:6231-6235
A series of SYK inhibitors based on the phenylamino pyrimidine thiazole lead 4 were prepared and evaluated for biological activity. Lead optimization provided compounds with nanomolar Ki’s against SYK and potent inhibition in mast cell degranulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2a734cf4205416eba869a8c2e13177
https://doi.org/10.1016/j.bmcl.2008.09.106
https://doi.org/10.1016/j.bmcl.2008.09.106
