Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Darshan Ranganathan"'
Autor:
Darshan Ranganathan, Isabella L. Karle
Publikováno v:
International Journal of Peptide and Protein Research. 46:24-29
The adipoyl- and suberoyl-linked bis(Ala) peptides have an extended backbone between the two C alpha atoms in each molecule. They self-assemble, through intermolecular hydrogen bonds and stacking of parallel strands, into highly ordered modified beta
Autor:
Darshan Ranganathan, Isabella K. Karle
Publikováno v:
International Journal of Peptide and Protein Research. 46:65-68
The backbone-modified tripeptide Bz-Aib-NHCOCO-Aib-OMe, in which the central C alpha has been replaced with CO, self-assembles in the solid state into highly ordered two-dimensional arrays through MeOH mediated intermolecular stacking of dimeric 'dis
Autor:
Darshan Ranganathan, I.L. Karle
Publikováno v:
The Journal of Peptide Research. 65:65-70
Molecules of 1,3,5-benzene tricarbonyl [Aib(4)OMe](3) do not possess any internal symmetry, neither exact nor approximate, in the crystalline state. The Aib(4)OMe moieties each form a 3(10)-helix with an appropriate pair of hydrogen bonds but the sen
Publikováno v:
Biopolymers. 89:471-478
The design, synthesis, conformational, crystallographic, and ion transport studies of 30-membered, proline containing depsipeptides that incorporate the rigid low molecular weight lipophilic adamantane (Adm) building blocks are reported. The adamanty
Autor:
Isabella L. Karle, Darshan Ranganathan
Publikováno v:
Journal of Molecular Structure. 647:85-96
Selected peptides and hybrid peptides (combinations of peptide sequences with organic moieties in a single molecule) self-assemble to form pores, channels and tubules. The assemblies occur in a variety of motifs. Various physiological functions, such
Publikováno v:
Journal of the American Chemical Society. 123:5619-5624
A novel family of cystine-based spirobicyclic peptides (cystinospiranes) has been synthesized by a single-step procedure involving condensation of pentaerythritol-derived tetrachloride with either the simple L-cystine dimethyl ester or its C,C'-exten
Publikováno v:
Biopolymers. 59:301-304
Autor:
Mariappanadar Vairamani, Darshan Ranganathan, Isabella L. Karle, A. C. Kunwar, A. V. S. Sarma, Sunita Kurur
Publikováno v:
The Journal of Peptide Research. 56:416-426
The design, synthesis, characterization and self-assembling properties of a new class of amphiphilic peptides, constructed from a bifunctional polar core attached to totally hydrophobic arms, are presented. The first series of this class, represented
Publikováno v:
Biopolymers. 54:289-295
The first generation molecule of glutamic acid-based dendrons on a 1,3,5-benzenetricarbonyl core leads to a cylindrical assembly as demonstrated by single crystal x-ray diffraction. The benzene π–π stack (A) is stabilized by vertical NH OC hy
Publikováno v:
Biopolymers. 54:249-261
Norbornene-supported bis-helical peptides with the general structure NBE(Aib(n) )(2) (NBE: 2,3-trans-norbornene dicarbonyl unit; Aib: alpha,alpha'-dimethyl glycine unit; n = 4,5) have been synthesized and examined for self-assembly preferences in the