Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Darshan N. Kasal"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Zbtb16-encoded transcription factor PLZF directs the differentiation of multiple innate and innate-like cell lineages, but how Zbtb16 itself is regulated remains unclear. Here the authors show, using CRISPR gene editing, ATAC-seq and ChIP-seq, that s
Externí odkaz:
https://doaj.org/article/8dd0fcd1a0814b67b951e8f0ed19db10
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
In the original PDF version of this Article, which was published on 16 October 2017, the publication date was incorrectly given as 11 October 2017. This has now been corrected in the PDF; the HTML version of the paper was correct from the time of pub
Externí odkaz:
https://doaj.org/article/8d28a32fa1a0464a93847114dd8a09cf
Autor:
Tyler E. Billipp, Connie Fung, Lily M. Webeck, Derek B. Sargent, Matthew B. Gologorsky, Margaret M. McDaniel, Darshan N. Kasal, John W. McGinty, Kaitlyn A. Barrow, Lucille M. Rich, Alessio Barilli, Mark Sabat, Jason S. Debley, Richard Myers, Michael R. Howitt, Jakob von Moltke
Publikováno v:
bioRxiv
Tuft cells are solitary chemosensory epithelial cells that can sense lumenal stimuli at mucosal barriers and secrete effector molecules to regulate the physiology and immune state of their surrounding tissue. In the small intestine, tuft cells detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a5077dec2253525a95e08a19d5a318
https://doi.org/10.1101/2023.03.17.533208
https://doi.org/10.1101/2023.03.17.533208
Autor:
Darshan N, Kasal, Zhitao, Liang, Maile K, Hollinger, Crystal Y, O'Leary, Wioletta, Lisicka, Anne I, Sperling, Albert, Bendelac
Publikováno v:
Proc Natl Acad Sci U S A
The type 2 helper effector program is driven by the master transcription factor GATA3 and can be expressed by subsets of both innate lymphoid cells (ILCs) and adaptive CD4(+) T helper (Th) cells. While ILC2s and Th2 cells acquire their type 2 differe
Autor:
Maile K. Hollinger, Anne I. Sperling, Darshan N. Kasal, Albert Bendelac, Zhitao Liang, Crystal Y O'Leary, Wioletta Lisicka
Publikováno v:
Proceedings of the National Academy of Sciences. 118
The type 2 helper effector program is driven by the master transcription factor GATA3 and can be expressed by subsets of both innate lymphoid cells (ILCs) and adaptive CD4+ T helper (Th) cells. While ILC2s and Th2 cells acquire their type 2 different
Autor:
Douglas E. Kline, Robbert M. Spaapen, Sravya Tumuluru, Xiufen Chen, Darshan N. Kasal, James Godfrey, Brendan W. MacNabb, Jovian Yu, Marlieke L.M. Jongsma, Justin Kline
Publikováno v:
SSRN Electronic Journal.
Antigen cross-presentation, wherein dendritic cells (DC) present exogenous antigen on MHC-I molecules, is considered the primary mechanism by which DCs initiate tumor-specific CD8+ T cell responses. Here, we demonstrate that MHC-dressing, an antigen
Autor:
Darshan N. Kasal, Albert Bendelac
Publikováno v:
The Journal of Experimental Medicine
Novel multi-transcription factor reporter mice were generated via CRISPR/Cas9 to dissect the developmental progression of ILC and LTi lineages. This study identifies lineage-specified precursors, indicating earlier bifurcation of ILC and LTi lineages
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Zbtb16-encoded PLZF is a signature transcription factor (TF) that directs the acquisition of T-helper effector programs during the development of multiple innate lymphocyte lineages, including natural killer T cell, innate lymphoid cell, mucosal-asso
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications
Nature Communications
Zbtb16-encoded PLZF is a signature transcription factor (TF) that directs the acquisition of T-helper effector programs during the development of multiple innate lymphocyte lineages, including natural killer T cell, innate lymphoid cell, mucosal-asso