Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Darryl W. Maher"'
Autor:
Darryl W. Maher, Richard Steele, David Langton, Lisa K. C. Pearce, William B Smith, Michael Gold, Marianne Empson, Leon Rozen, Joanne Smart, John B. Ziegler, Mimi L.K. Tang, Constance H. Katelaris
Publikováno v:
Journal of Clinical Immunology. 32:897-906
This phase III, open-label, multi-centre study investigated the efficacy, safety, pharmacokinetics and quality of life impact of Evogam(®), a new chromatographically fractionated 16% subcutaneous immunoglobulin, utilising a 1:1 dose transition ratio
Autor:
Karl Bleasel, Robert G Stirling, Darryl W. Maher, Robert J. Heddle, Carolyn Stone, Pravin Hissaria
Publikováno v:
Internal Medicine Journal. 42:252-259
Background and aims: Intragam® 10 NF is the next generation 10% intravenous immunoglobulin with three pathogen reduction steps and a noncarbohydrate stabiliser. This open label, cross-over study in patients with primary immunodeficiency was designed
Autor:
John W Wilson, Jeffrey J. Presneill, Darryl W. Maher, John F. Cade, Jonathan Cebon, Paul Waring, Judith E. Layton, Nerina Harley
Publikováno v:
Critical Care Medicine. 28:2344-2354
To define the circulating levels of granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) during critical illness and to determine their relationship to the severity of illness as measured by the
Autor:
Russell L. Basser, Richard M. Fox, Jonathan Cebon, John S. Hill, Andrew H. Kaye, Kerrie Clarke, Howard Geldard, Michael D. Green, Carole Alt, Jane Bartlett, Denis J. Morgan, Darryl W. Maher
Publikováno v:
Journal of Clinical Oncology. 16:2181-2187
PURPOSE To determine the recommended dose, toxicity profile, and pharmacokinetics of KRN8602 (MX2-hydrochloride), a novel morpholino anthracycline with potent cytotoxicity against anthracycline-sensitive and resistant experimental tumors in vitro and
Autor:
Jonathan Cebon, Howard Geldard, Denis J. Morgan, Kerrie Clarke, Darryl W. Maher, John S. Hill, Andrew H. Kaye, Michael D. Green, Russell L. Basser, Samantha J Park, Stan S. Stylli
Publikováno v:
Cancer Chemotherapy and Pharmacology. 41:423-426
Purpose: To investigate the effect of granulocyte colony-stimulating factor (G-CSF) on the pharmacokinetics and pharmacodynamics of the new morpholino anthracycline drug MX2. Methods: A total of 25 patients with advanced malignant disease participate
Autor:
Kerrie Clarke, Jonathan Cebon, Samantha J Park, John S. Hill, Andrew H. Kaye, Michael D. Green, Darryl W. Maher, Stan S. Stylli, Russell L. Basser, Denis J. Morgan, Howard Geldard
Publikováno v:
Cancer Chemotherapy and Pharmacology. 40:202-208
The purpose of the present study was to investigate the pharmacokinetics and pharmacodynamics of the new morpholino anthracycline drug MX2. A total of 27 patients with advanced cancer participated in a dose-escalation study in the first cycle of trea
Autor:
Katherine M McGrath, Darryl W. Maher, Sue Houghton, Andrew Grigg, Andrew W. Boyd, Judith E. Layton, Heike Raunow, Andrew W. Roberts
Publikováno v:
Blood. 86:4437-4445
To define an optimal regimen for mobilizing and collecting peripheral blood progenitor cells (PBPC) for use in allogeneic transplantation, we evaluated the kinetics of mobilization by filgrastim (recombinant met- human granulocyte colony-stimulating
Autor:
Jonathan Cebon, Vincent Sinickas, John A. M. Gall, Donald Metcalf, George Hodgson, Darryl W. Maher, Dianne Grail, Graham J. Lieschke, Edouard G. Stanley, Ashley R. Dunn
Publikováno v:
Proceedings of the National Academy of Sciences. 91:5592-5596
Mice homozygous for a disrupted granulocyte/macrophage colony-stimulating factor (GM-CSF) gene develop normally and show no major perturbation of hematopoiesis up to 12 weeks of age. While most GM-CSF-deficient mice are superficially healthy and fert
Publikováno v:
British Journal of Haematology. 86:265-274
Haemopoietic growth factors (HGFs) are being administered to patients with neutropenic fever; however, little is known about the endogenous HGF response in these patients. Specific assays were used to study four HGFs, granulocyte (G-) CSF, granulocyt