Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Darryl Rideout"'
Autor:
Martha Mutomba, Jing Wang, Sergei Mailiartchouk, Tom Brady, Darryl Rideout, Christina Niemeyer, Hengyi Zhu, Cindy Fisher, Seymour Mong, Kal Ramnarayan
Publikováno v:
The Scientific World Journal, Vol 1, Pp 107-107 (2001)
Externí odkaz:
https://doaj.org/article/6a0522389a53490fa8fa89937ced89f9
Publikováno v:
Clinical & Experimental Pharmacology.
Objective: Novel agents to treat metastatic prostate cancer include a class of drugs which function primarily by inhibiting the action of the CYP17 enzyme, which results in decreased androgen synthesis. Abiraterone and related molecules have been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295434992cc4856045d57ae7b843f499
https://doi.org/10.4172/2161-1459.1000173
https://doi.org/10.4172/2161-1459.1000173
Publikováno v:
International Journal of Cancer. 61:840-847
Suramin is an experimental anti-neoplastic agent which has shown promising activity against prostatic carcinoma and lymphoma in clinical trials. To elucidate its mechanism of action, suramin was examined for an effect on the transport of folate compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00232046ed57f4ffec1069aca7652a71
https://doi.org/10.1002/ijc.2910610616
https://doi.org/10.1002/ijc.2910610616
Autor:
Darryl Rideout
Publikováno v:
Cancer Investigation. 12:189-202
(1994). Self-Assembling Drugs: A New Approach to Biochemical Modulation in Cancer Chemotherapy. Cancer Investigation: Vol. 12, No. 2, pp. 189-202.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0dedb1a0fa1f36eab344499b6c10ab
https://doi.org/10.3109/07357909409024874
https://doi.org/10.3109/07357909409024874
Publikováno v:
Leukemia Research. 17:247-253
Lipophilic cationic compounds accumulate more rapidly in the mitochondria of many carcinoma-derived cells than in non-transformed cells, thus leading to their pronounced cytotoxic effects on carcinoma cells. In this report, in order to measure tumori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e939c28f2c38036cadb31eaaa2b571f
https://doi.org/10.1016/0145-2126(93)90008-9
https://doi.org/10.1016/0145-2126(93)90008-9
Autor:
Christina Niemeyer, J. Sun, Jian Hua Zheng, S. H. Leppla, Venkatachalapathi V. Yalamoori, N. Duesberry, Kalyanaraman Ramnarayan, Mark D. Shenderovich, M. G. de Luna, Darryl Rideout
Publikováno v:
Peptides: The Wave of the Future ISBN: 9789401039055
Bacillus anthracis, the cause of anthrax, poses a considerable danger because of its potential use as a weapon by military organizations and terrorist groups. Respiratory anthrax infections are almost invariably fatal despite antibiotic treatment. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::601f1dd4830df740806527a81bbb2ef6
https://doi.org/10.1007/978-94-010-0464-0_310
https://doi.org/10.1007/978-94-010-0464-0_310
Autor:
Andres Bustamante, Alberto Manetta, Dennis Emma, Jasmin Patel, Philip M. Carpenter, Gisela Gamboa, Darryl Rideout, Yale D. Podnos, Luke Rawlings, Guillermo Dorion, Amir Nasseri
Publikováno v:
Gynecologic oncology. 60(2)
Phosphonium salts are part of a class of lipophilic cationic molecules that accumulate preferentially in mitochondria and inhibit the growth of human and rodent carcinoma cells in vitro and in animal models. The delocalized cations tested previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbeef07984a1a23594fe6d8526c8abad
https://pubmed.ncbi.nlm.nih.gov/8631539
https://pubmed.ncbi.nlm.nih.gov/8631539
Publikováno v:
International journal of cancer. 57(2)
Cationic phosphonium salts are interesting because they inhibit the proliferation of carcinoma cells more than untransformed epithelial cells in vitro. This differential anti-proliferative effect has been used to identify phosphonium salts and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fd7f7687c50223f417ed7e2d865d05
https://pubmed.ncbi.nlm.nih.gov/8157363
https://pubmed.ncbi.nlm.nih.gov/8157363
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 90(21)
Highly sensitive and convenient analysis of intracellular cationic drugs has been achieved by applying matrix-assisted laser desorption/ionization mass spectrometry (MALD-MS). Tetraphenylphosphonium cation was readily identified and quantified (using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfa5dcb7dbcb7b168762f6b4cd1cd62
https://pubmed.ncbi.nlm.nih.gov/8234281
https://pubmed.ncbi.nlm.nih.gov/8234281
Autor:
Cindy Fisher, Darryl Rideout, Kal Ramnarayan, Hengyi Zhu, Martha Mutomba, Sergei Mailiartchouk, Jing Wang, Christina Niemeyer, Seymour Mong, Thomas J. Brady
Publikováno v:
The Scientific World Journal
The Scientific World Journal, Vol 1, Pp 107-107 (2001)
The Scientific World Journal, Vol 1, Pp 107-107 (2001)
METHODS. The NMR structure of Bcl-xL complexed with a portion of the BH3 region of its ligand Bak (PDB accession number 1BXL) (6) was used to generate a computational model of Bcl-2 complexed with a corresponding portion of its intracellular ligand B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa3406f1d54ab8b7ed3cc8ff2557bcd
https://doi.org/10.1100/tsw.2001.23.124
https://doi.org/10.1100/tsw.2001.23.124