Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Darryl J. Pappin"'
Autor:
Ezequiel Dantas, Anirudh Murthy, Tanvir Ahmed, Mujmmail Ahmed, Shakti Ramsamooj, Maurice A. Hurd, Tiffany Lam, Murtaza Malbari, Christopher Agrusa, Olivier Elemento, Chen Zhang, Darryl J. Pappin, Timothy E. McGraw, Brendon M. Stiles, Nasser K. Altorki, Marcus D. Goncalves
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background Lung cancer remains the major cause of cancer‐related deaths worldwide. Early stages of lung cancer are characterized by long asymptomatic periods that are ineffectively identified with the current screening programs. This defic
Externí odkaz:
https://doaj.org/article/9f3f0facc0d04731a5086808193bc9a9
Autor:
Kung-Chi Chang, Sarah D. Diermeier, Allen T. Yu, Lily D. Brine, Suzanne Russo, Sonam Bhatia, Habeeb Alsudani, Karen Kostroff, Tawfiqul Bhuiya, Edi Brogi, Darryl J. Pappin, C. Frank Bennett, Frank Rigo, David L. Spector
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
A group of long non-coding RNAs (lncRNAs), Mammary Tumor Associated RNA s 1-30 (MaTARs 1-30), are differentially expressed between mammary tumor cells and normal mammary epithelial cells. Here the authors report that MaTAR25 plays a role in breast ca
Externí odkaz:
https://doaj.org/article/6dafc61ca8e54b14af09f6dca2979a49
Autor:
Adam Naguib, Grinu Mathew, Colleen R. Reczek, Kaitlin Watrud, Alexandra Ambrico, Tali Herzka, Irene Casanova Salas, Matthew F. Lee, Nour El-Amine, Wu Zheng, M. Emilia Di Francesco, Joseph R. Marszalek, Darryl J. Pappin, Navdeep S. Chandel, Lloyd C. Trotman
Publikováno v:
Cell Reports, Vol 23, Iss 1, Pp 58-67 (2018)
Summary: A hallmark of advanced prostate cancer (PC) is the concomitant loss of PTEN and p53 function. To selectively eliminate such cells, we screened cytotoxic compounds on Pten−/−;Trp53−/− fibroblasts and their Pten-WT reference. Highly se
Externí odkaz:
https://doaj.org/article/ef92114328e64222bc2c836f7460a8f4
Autor:
Gyula Bencze, Szilvia Bencze, Keith D. Rivera, James D. Watson, Mate Hidvegi, Laszlo Orfi, Nicholas K. Tonks, Darryl J. Pappin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/c47f7a261d114bd4873160c6a67d63d1
Autor:
Adam Naguib, Gyula Bencze, Dannielle D. Engle, Iok I.C. Chio, Tali Herzka, Kaitlin Watrud, Szilvia Bencze, David A. Tuveson, Darryl J. Pappin, Lloyd C. Trotman
Publikováno v:
Cell Reports, Vol 10, Iss 1, Pp 8-19 (2015)
Phosphatidylinositol phosphate (PIP) second messengers relay extracellular growth cues through the phosphorylation status of the inositol sugar, a signal transduction system that is deregulated in cancer. In stark contrast to PIP inositol head-group
Externí odkaz:
https://doaj.org/article/53b18fd79ede4d1d8913e6ee1a3bf047
Autor:
Allen T Yu, Carmen Berasain, Sonam Bhatia, Keith Rivera, Bodu Liu, Frank Rigo, Darryl J Pappin, David L Spector
Publikováno v:
eLife, Vol 10 (2021)
Hepatocellular carcinoma, the most common type of liver malignancy, is one of the most lethal forms of cancer. We identified a long non-coding RNA, Gm19705, that is overexpressed in hepatocellular carcinoma and mouse embryonic stem cells. We named th
Externí odkaz:
https://doaj.org/article/72f24e0d4ca04037b061615c66b60f36
Autor:
Ming Zhu, Darryl J. Pappin, Li-Yuan Yu-Lee, Christopher J. Logothetis, Sue-Hwa Lin, Theocharis Panaretakis, Yu Chen Lee, Guoyu Yu, Jian H. Song, Keith Rivera, Song-Chang Lin, Guocan Wang
Publikováno v:
Oncogene. 41:757-769
Metastatic prostate cancer (PCa) in bone induces bone-forming lesions that enhance PCa progression. How tumor-induced bone formation enhances PCa progression is not known. We have previously shown that PCa-induced bone originates from endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d13f63e228f582049b00a5725a6ce3c7
https://doi.org/10.1038/s41388-021-02131-7
https://doi.org/10.1038/s41388-021-02131-7
Publikováno v:
Journal of Biological Chemistry. 299:104582
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75ee6903e49e853dfe42681fde30724
https://doi.org/10.1016/j.jbc.2023.104582
https://doi.org/10.1016/j.jbc.2023.104582
Autor:
David L. Spector, C. Frank Bennett, Kung-Chi Chang, Suzanne Russo, Tawfiqul Bhuiya, Sarah D. Diermeier, Edi Brogi, Darryl J. Pappin, Frank Rigo, Lily D. Brine, Karen Kostroff, Sonam Bhatia, Allen T. Yu, Habeeb Alsudani
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications
Misregulation of long non-coding RNA (lncRNA) genes has been linked to a wide variety of cancer types. Here we report on Mammary Tumor Associated RNA 25 (MaTAR25), a nuclear enriched and chromatin associated lncRNA that plays a role in mammary tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578b1f2f3824b5a546706d238916b057
https://doaj.org/article/6dafc61ca8e54b14af09f6dca2979a49
https://doaj.org/article/6dafc61ca8e54b14af09f6dca2979a49
Autor:
John P. Wilson, Darryl J. Pappin, Jonathan J. Ipsaro, Keith Rivera, Katharine H. Dusenbury, Krisann Marquart, Nikita Saha Turna, Carla M. Gauss, Samantha N. Del Giudice
Publikováno v:
J Proteome Res
Bottom-up proteomics is a mainstay in protein identification and analysis. These studies typically employ proteolytic treatment of biological samples to generate suitably sized peptides for tandem mass spectrometric (MS) analysis. In MS, fragmentatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad33f53423abf67807b4b9f8027eba74
https://doi.org/10.1021/acs.jproteome.9b00713
https://doi.org/10.1021/acs.jproteome.9b00713