Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Darryl J, Bornhop"'
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-6 (2021)
Abstract Background Lysophosphatidic acid (LPA) is a bioactive lysophospholipid that acts through its six cognate G protein-coupled receptors. As a family, lysophospholipids have already produced medicines (e.g., sphingosine 1-phosphate) as is being
Externí odkaz:
https://doaj.org/article/576572a9f27f4093997e939f6ad6b2f0
Autor:
Manisha Ray, Kazufumi Nagai, Yasuyuki Kihara, Amanda Kussrow, Michael N. Kammer, Aaron Frantz, Darryl J. Bornhop, Jerold Chun
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 8, Pp 1244-1251 (2020)
Native interactions between lysophospholipids (LPs) and their cognate LP receptors are difficult to measure because of lipophilicity and/or the adhesive properties of lipids, which contribute to high levels of nonspecific binding in cell membrane pre
Externí odkaz:
https://doaj.org/article/07f8a7465ce3454baabeb0ede8698fc2
Publikováno v:
ACS Omega, Vol 5, Iss 20, Pp 11308-11313 (2020)
Externí odkaz:
https://doaj.org/article/981a57b1d0a94dac84ab395f7f7f5ceb
Autor:
Hirotaka Mizuno, Yasuyuki Kihara, Amanda Kussrow, Allison Chen, Manisha Ray, Richard Rivera, Darryl J. Bornhop, Jerold Chun
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 1, Pp 212-217 (2019)
Lysophosphatidic acid (LPA) activates cognate G protein-coupled receptors (GPCRs) to initiate biological signaling cascades. Lysophospholipid (LP) receptor binding properties remain incompletely assessed because of difficulties with ligand lipophilic
Externí odkaz:
https://doaj.org/article/d948ee567305430cb11b204332660981
Publikováno v:
ACS Omega. 7:31916-31923
CYFRA 21.1, a cytokeratin fragment of epithelial origin, has long been a valuable blood-based biomarker. As with most biomarkers, the clinical diagnostic value of CYFRA 21.1 is dependent on the quantitative performance of the assay. Looking toward tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a3a78eb400913991ea93a92d376df6
https://doi.org/10.1021/acsomega.2c02763
https://doi.org/10.1021/acsomega.2c02763
Autor:
Robert J. Coffey, Darryl J. Bornhop, Bruce A. Aronow, M. Kay Washington, A. Coe Foutch, H. Charles Manning, Natasha G. Deane
Supplementary Figure S1 from Targeted Imaging of Colonic Tumors in Smad3−/− Mice Discriminates Cancer and Inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c991782ffe29adce883ed3c3b81557
https://doi.org/10.1158/1541-7786.22521180.v1
https://doi.org/10.1158/1541-7786.22521180.v1
Autor:
Robert J. Coffey, John C. Gore, Darryl J. Bornhop, Mace L. Rothenberg, Ronald M. Baldwin, M. Sib Ansari, Todd E. Peterson, Mohammed Noor Tantawy, Bonnie LaFleur, M. Kay Washington, Nathan J. Mutic, Jingping Xie, Eliot T. McKinley, Chirayu Shah, Shelby K. Wyatt, John M. Virostko, A. Coe Foutch, Nipun B. Merchant, H. Charles Manning
Purpose: To evaluate noninvasive molecular imaging methods as correlative biomarkers of therapeutic efficacy of cetuximab in human colorectal cancer cell line xenografts grown in athymic nude mice. The correlation between molecular imaging and immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447b9a40084e020ea7db55de79154c60
https://doi.org/10.1158/1078-0432.c.6517170
https://doi.org/10.1158/1078-0432.c.6517170
Autor:
Robert J. Coffey, John C. Gore, Darryl J. Bornhop, Mace L. Rothenberg, Ronald M. Baldwin, M. Sib Ansari, Todd E. Peterson, Mohammed Noor Tantawy, Bonnie LaFleur, M. Kay Washington, Nathan J. Mutic, Jingping Xie, Eliot T. McKinley, Chirayu Shah, Shelby K. Wyatt, John M. Virostko, A. Coe Foutch, Nipun B. Merchant, H. Charles Manning
Supplementary Figures S1-S4 from Molecular Imaging of Therapeutic Response to Epidermal Growth Factor Receptor Blockade in Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d3b5f977abfcdeb72512ec0826fd3d
https://doi.org/10.1158/1078-0432.22439745
https://doi.org/10.1158/1078-0432.22439745
Publikováno v:
ACS Omega, Vol 5, Iss 35, Pp 22683-22683 (2020)
Externí odkaz:
https://doaj.org/article/2f0c6a1d08f54b7d85272878e9954dcd
Autor:
Amanda Kussrow, Yasuyuki Kihara, Kazufumi Nagai, Michael N. Kammer, Manisha Ray, Darryl J. Bornhop, Aaron Frantz, Jerold Chun
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 8, Pp 1244-1251 (2020)
Journal of Lipid Research
Journal of Lipid Research
Native interactions between lysophospholipids (LPs) and their cognate LP receptors are difficult to measure because of lipophilicity and/or the adhesive properties of lipids, which contribute to high levels of nonspecific binding in cell membrane pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19c521184c5e01d54c42c8468bc5dc1
https://doi.org/10.1194/jlr.d120000880
https://doi.org/10.1194/jlr.d120000880