Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Darryl H. Patrick"'
Autor:
Howard Y. Chen, Chennekatu P. Peter, Lea G. Stabinski, Dan Holder, Darryl H. Patrick, Srinivasa Prahalada, Richard E. Morrissey, Matthew J. van Zwieten, Georges De Burlet
Publikováno v:
Toxicologic Pathology. 26:185-200
The purpose of this study was to evaluate the pharmacological and toxicological effects of exogenous GH administration in normal adult dogs. Because porcine GH (pGH) is structurally identical to canine GH, pGH was selected for a 14-wk study in dogs.
Autor:
Charles Anderson, David W. Alberts, Scott J. Grossman, Darryl H. Patrick, Ronald S. Eydelloth, Neil Reinford, Peter F. Smith
Publikováno v:
Toxicology and Applied Pharmacology. 146:40-52
Oral administration of the HIV protease inhibitor L-689,502 caused cholestasis and hepatocyte injury in rats and dogs. These changes occurred rapidly, with elevations in serum transaminase observed as early as 6 hr after oral dosing in dogs. The acut
Autor:
Darryl H. Patrick, G. Durand-Cavagna, Jean-Pierre Gillet, Pierre Duprat, Anna C. Huber, Sylvain Molon-Noblot
Publikováno v:
Toxicologic pathology. 24(2)
The direct 5-lipoxygenase inhibitor L-739,010 was administered at a dose of 60 mg/kg/day per os to beagle dogs for 15 days. Histopathological examination of gallbladders from treated dogs showed epithelial vacuolation and submucosal infiltration by f
Autor:
Robert E. Wolf, David J. Cohen, Michael C. Hotard, Geoffrey M. Graeber, Rostik Zajtchuk, Darryl H. Patrick
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 25:903-908
Sixteen dogs were placed under general anesthesia and flail segments of the left chest were created by transecting ribs 7,8,9, and 10 anteriorly and posteriorly. Fractures were 10 cm apart so that a 10-cm flail segment encompassing four ribs was crea
Publikováno v:
Journal of Neurosurgery. 60:712-717
✓ Corticosteroids are frequently used in the treatment of spinal trauma, although neither experimental nor clinical evidence to support their use is persuasive. Recently there have been claims that extremely high doses (“megadoses”) of corticos
Publikováno v:
Journal of the Neurological Sciences. 73:55-60
The myelin-specific ganglioside GM4, when incubated with myelin basic protein prior to inoculation, prevents experimental allergic encephalomyelitis in the guinea pig. The monosialoganglioside GM1, the predominant ganglioside of mammalian myelin, als
Autor:
Geoffrey M. Graeber, Carmel M. Cordova, Donald O. Castell, Abraham H. Dachman, Stanley B. Benjamin, Darryl H. Patrick, David J. Cohen, Arnold C. Friedman
Publikováno v:
The Annals of Thoracic Surgery. 41:135-142
Minimal data are available about the Angelchik antireflux prosthesis although it has been inserted in more than 14,000 patients. The present animal study was designed to evaluate the effectiveness and mechanism of action of this prosthesis. A reprodu
Natural history of the obstructed rabbit appendix: observations with radiography, sonography, and CT
Publikováno v:
AJR. American journal of roentgenology. 148(2)
Chronic (1-3 months' duration) appendiceal obstruction was induced in 11 rabbits to assess the pathologic consequences and to study the associated radiologic, sonographic, and CT findings. Three pathologic/radiologic groups resulted with approximatel
Publikováno v:
Brain research. 296(1)
Guinea pigs inoculated with a mixture of myelin basic protein and the myelin-specific ganglioside, sialosylgalactosylceramide (GM4), do not develop the signs or neuropathology of experimental allergic encephalomyelitis. The results indicate that GM4
Publikováno v:
Investigative Radiology. 21:S2