Výsledky vyhledávání - "Darrow E. Haagensen"

Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

Autor: Jonathan D. Smith, Songwen Zhang, Monty Krieger, Fumiyuki Otsuka, Frank D. Kolodgie, Ronglih Liao, Kosuke Tsukamoto, D. R. Mani, Wei Weng, Jianru Shi, Darrow E. Haagensen, Renu Virmani, Jian Guan

Publikováno v: Proceedings of the National Academy of Sciences

Mice with homozygous null mutations in the HDL receptor (scavenger receptor class B, type I, or SR-BI) and apolipoprotein E (apoE) genes [SR-BI/apoE double KO (SR-BI(-/-)/apoE(-/-) or dKO) mice] spontaneously develop occlusive, atherosclerotic corona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c64116f7d2e63befc252ca9c2b64a64
https://doi.org/10.1073/pnas.1315986110

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IMMUNOLOCALIZATION OF APOLIPOPROTEIN D, ANDROGEN RECEPTOR AND PROSTATE SPECIFIC ANTIGEN IN EARLY STAGE PROSTATE CANCERS

Autor: Jacqueline M. Bentel, David J. Horsfall, Villis R. Marshall, Darrow E. Haagensen, Wayne D. Tilley, Carmela Ricciardelli, Steven X.D. Zhang

Publikováno v: Journal of Urology. 159:548-554

Purpose: To determine the cellular distribution and levels of immunohistochemical staining for apolipoprotein D (Apo-D), prostate specific antigen (PSA) and androgen receptor (AR) in early stage prostate cancers.Materials and Methods: Cellular distri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104c0ab3b6a58d5fbe3753a8b13a1524
https://doi.org/10.1016/s0022-5347(01)63981-8

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Interleukin-6 inhibits the potent stimulatory action of androgens, glucocorticoids and interleukin-1α on apolipoprotein D and GCDFP-15 expression in human breast cancer cells

Autor: Keiko Sugimoto, Yves Blais, Jacques Simard, Marie-Claude Carrière, Fernand Labrie, Darrow E. Haagensen

Publikováno v: International Journal of Cancer. 62:732-737

Our study was designed to investigate the potential interaction between steroid hormones and interleukin-6 (IL-6) in the regulation of apolipoprotein D (apo-D) and gross cystic disease fluid protein 15 (GCDFP-15) expression in ZR-75-1 human breast ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c9a63b6567a1d9dfddc23ca0d5089c
https://doi.org/10.1002/ijc.2910620614

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Is Cystic Disease Related to Breast Cancer?

Autor: Darrow E. Haagensen

Publikováno v: The American Journal of Surgical Pathology. 15:687-694

Human breast cystic disease is a common premenopausal benign breast condition. Apocrine metaplasia of normal breast epithelium is the lesion that allows cysts to develop. Apocrine metaplasia and breast cysts occur frequently in association with other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db092b9e8225af5a36969e5274f127e5
https://doi.org/10.1097/00000478-199107000-00010

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Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression in human breast cancer cells

Autor: Sebastien Gingras, Yves Blais, Jacques Simard, Fernand Labrie, Darrow E. Haagensen

Publikováno v: Molecular and cellular endocrinology. 121(1)

Human breast carcinomas are frequently infiltrated by inflammatory cells secreting several cytokines which may regulate the activity of both immune cells and neoplastic cells. The present study was designed to examine the potential action of interleu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dff6ad34dce2d3f72e8bc88e7f6472
https://pubmed.ncbi.nlm.nih.gov/8865161

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Differential expression of apolipoprotein-D and prostate specific antigen in benign and malignant prostate tissues

Autor: Wayne D. Tilley, Darrow E. Haagensen, Jacqueline M. Bentel, David J. Horsfall, Villis R. Marshall, James O. Aspinall

Publikováno v: The Journal of urology. 154(2 Pt 1)

Purpose: To investigate Apolipoprotein-D (Apo-D) and prostate specific antigen (PSA) immunohistochemical staining of nonmalignant and malignant human prostate tissues.Materials and Methods: Apolipoprotein-D and PSA immunoreactivity were evaluated by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b7adef5427e97363e2403aba29fe65
https://pubmed.ncbi.nlm.nih.gov/7541868

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Mitogenic effect of the 15-kDa gross cystic disease fluid protein (GCDFP-15) on breast-cancer cell lines and on immortal mammary cells

Autor: Darrow E. Haagensen, Anna Sapino, Paola Cassoni, Gianni Bussolati, Carlo Naldoni

The biological significance of a major protein component in the fluid of gross cystic breast disease and a recognized marker of apocrine metaplasia, i.e. the 15-kDa glycoprotein (GCDFP-15), is presently unknown. We have added GCDFP-15 to cell culture

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e6994db0c279a189ed1964c73bf0d7
http://hdl.handle.net/2318/29217

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Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells

Autor: Fernand Labrie, Darrow E. Haagensen, Keiko Sugimoto, Jacques Simard

Publikováno v: The Journal of steroid biochemistry and molecular biology. 51(3-4)

We have recently demonstrated that the biphasic action of androgens on LNCaP cell proliferation is opposite to their effect on apolipoprotein D (apo-D) secretion, the stimulation of apo-D secretion being associated with a steroid-induced inhibition o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0ced36672a1d62ce96b32424e5fd67
https://pubmed.ncbi.nlm.nih.gov/7526888

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