Human melanoma-mediated inhibition of autologous CD4+ helper tumor-infiltrating lymphocyte growth in vitro.

Autor: Darrow, Timothy L., Wahab, Zeinab, Quinn-Allen, Mary Ann, Seigler, Hilliard F., Darrow, T L, Wahab, Z, Quinn-Allen, M A, Seigler, H F

Publikováno v: Cancer (0008543X); Apr1992, Vol. 69 Issue 7, p1843-1849, 7p

Melanoma-specific cytotoxic T cells generated from peripheral blood lymphocytes. Implications of a renewable source of precursors for adoptive cellular immunotherapy

Autor: Slingluff, C L, Darrow, T L, Seigler, H F

Cytotoxic T lymphocytes (CTL) specific for autologous human melanoma have been generated in vitro from peripheral blood lymphocytes (PBL) of five patients with resectable stage II malignant melanoma. The PBL were cultured with 5u/ml recombinant IL-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1fb5ec4a396080d98f696c6f4d3bab0
https://europepmc.org/articles/PMC1357828/

Dendritic cells infected with a vaccinia vector carrying the human gp100 gene simultaneously present multiple specificities and elicit high-affinity T cells reactive to multiple epitopes and restricted by HLA-A2 and -A3.

Autor: Yang S; Department of Surgery, Duke University Medical Center, Durham, NC 27710; and Department of Surgery, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA., Kittlesen D, Slingluff CL Jr, Vervaert CE, Seigler HF, Darrow TL

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2000 Apr 15; Vol. 164 (8), pp. 4204-11.

Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity.

Autor: Yang S; Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA., Vervaert CE, Burch J Jr, Grichnik J, Seigler HF, Darrow TL

Publikováno v: International journal of cancer [Int J Cancer] 1999 Nov 12; Vol. 83 (4), pp. 532-40.

Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow.

Autor: Yang S; Duke University Medical Center, Department of Surgery, Durham, North Carolina 27710, USA., Darrow TL, Vervaert CE, Seigler HF

Publikováno v: Cellular immunology [Cell Immunol] 1997 Jul 10; Vol. 179 (1), pp. 84-95.