Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Darrin J. Bast"'
Publikováno v:
FEMS Immunology & Medical Microbiology. 51:547-554
Streptococcus iniae causes invasive disease and death in fish, and to a lesser extent, sporadic cases of soft-tissue infections in humans. A two-component system termed sivS/R, which regulates capsule expression, was previously identified and charact
Publikováno v:
Infection and Immunity. 75:5011-5017
Streptococcus pyogenes is a ubiquitous and versatile pathogen that causes a variety of infections with a wide range of severity. The versatility of this organism is due in part to its capacity to regulate virulence gene expression in response to the
Publikováno v:
FEMS Immunology & Medical Microbiology. 50:366-374
Streptococcus iniae causes disease in fish and humans and the presence of capsule is associated with virulence. Tn917 transposon mutagenesis was performed to identify capsule-associated genes and a mutant was isolated, with an insertion in a genetic
Autor:
Dennis G. Cvitkovitch, Joyce C. S. de Azavedo, Peter Chang, Kowthar Y. Salim, Martin Handfield, Jeffrey D. Hillman, Darrin J. Bast
Publikováno v:
Infection and Immunity. 73:6026-6038
Group A Streptococcus (GAS) causes a range of diseases in humans, from mild noninvasive infections to severe invasive infections. The molecular basis for the varying severity of disease remains unclear. We identified genes expressed during invasive d
Publikováno v:
Journal of Antimicrobial Chemotherapy. 54:424-428
OBJECTIVE: Long-term therapy for anthrax might induce antimicrobial resistance in Bacillus anthracis. The aim of the present study was to investigate the potential of 18 different antibiotics to select resistant isolates of B. anthracis, (ST-1 and St
Autor:
Galia Rahav, Carla Duncan, Joyce C. S. de Azavedo, Ethan Rubinstein, Darrin J. Bast, Abed Athamna, David J. Farrell, Donald E. Low
Publikováno v:
Journal of Antimicrobial Chemotherapy. 54:90-94
Received 20 January 2004; returned 9 March 2004; revised 19 April 2004; accepted 21 April 2004Objectives: To identify and characterize the mechanisms of high-level fluoroquinolone resistancein two strains of Bacillus anthracis following serial passa
Autor:
M. Massalha, Darrin J. Bast, B. Medlej, Ethan Rubinstein, A. Nura, Muhammad Athamna, A. Athamna, Itzhak Ofek
Publikováno v:
Journal of Antimicrobial Chemotherapy. 53:247-251
OBJECTIVES To investigate the in vitro acquisition of resistance to antibiotics by Bacillus anthracis. METHODS The in vitro activities of 18 antibacterial agents against two strains of B. anthracis, the Sterne strain and the Russian anthrax vaccine s
Publikováno v:
Emerging Infectious Diseases
Scopus-Elsevier
Emerging Infectious Diseases, Vol 9, Iss 7, Pp 833-837 (2003)
Scopus-Elsevier
Emerging Infectious Diseases, Vol 9, Iss 7, Pp 833-837 (2003)
The emergence of Streptococcus pneumoniae resistance to β-lactam and macrolide antimicrobial agents has led to recommendations that fluoroquinolones with increased activity against S. pneumoniae, such as levofloxacin, moxifloxacin, and gatifloxacin,
Autor:
Michel Laverdière, Allison McGeer, Ross J. Davidson, C. Restieri, Richard Gauthier, Darrin J. Bast, Karl Weiss, Laurie Kilburn, Joyce C. S. de Azavedo, Donald E. Low
Publikováno v:
Clinical Infectious Diseases. 33:517-522
Over the course of a 20-month period, in a hospital respiratory ward in which ciprofloxacin was often used as empirical antimicrobial therapy for lower respiratory tract infections (LRTIs), 16 patients with chronic bronchitis developed nosocomial LRT
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:1911-1914
To determine if susceptibility testing of Streptococcus pneumoniae could detect those isolates that had one of the recognized mechanisms of fluoroquinolone resistance, 101 isolates were selected; the levofloxacin MIC for 28 of these isolates was ≥4