Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Darrin J, Pochan"'
Autor:
Yi Shi, Tianren Zhang, Rui Guo, Zihan Zhang, Amanda L. McCahill, Yao Tang, Sabrina E. Liskey, Dai-Bei Yang, Christopher J. Kloxin, Jeffery G. Saven, Darrin J. Pochan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Surface charge patchiness of different charge types can influence the solution behaviours of colloidal particles and globular proteins. Herein, coiled-coil ‘bundlemer’ nanoparticles that display only a single type of surface charge (SC)
Externí odkaz:
https://doaj.org/article/b94d0f201150413c91aa62fbc09c883f
Autor:
Garrett A. Taggart, Aynur Guliyeva, Kyunghee Kim, Glenn P. A. Yap, Darrin J. Pochan, Thomas H. Epps, Eric D. Bloch
Publikováno v:
The Journal of Physical Chemistry C. 127:2379-2386
Autor:
José A. Villegas, Nairiti J. Sinha, Naozumi Teramoto, Christopher D. Von Bargen, Darrin J. Pochan, Jeffery G. Saven
Publikováno v:
Molecules, Vol 27, Iss 4, p 1237 (2022)
Protein complexes perform a diversity of functions in natural biological systems. While computational protein design has enabled the development of symmetric protein complexes with spherical shapes and hollow interiors, the individual subunits often
Externí odkaz:
https://doaj.org/article/4dd44c25805643cfbc50ead2fc68fde3
Autor:
Hao Qi, Hao Zhou, Qiyun Tang, Jee Young Lee, Zhiyuan Fan, Seyong Kim, Mark C. Staub, Tian Zhou, Shan Mei, Lin Han, Darrin J. Pochan, Hao Cheng, Wenbing Hu, Christopher Y. Li
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
In block copolymer vesicles, crystallization often leads to defects and renders the structures leaky that undermines their potential biomedical application. Here the authors use an emulsion solution method to control the crystallization of an amphiph
Externí odkaz:
https://doaj.org/article/cf1b0e80e6504b16bf9de4272a6c4ba7
Autor:
Sai S. Patkar, Yao Tang, Arriana M. Bisram, Tianren Zhang, Jeffery G. Saven, Darrin J. Pochan, Kristi L. Kiick
Publikováno v:
Angewandte Chemie International Edition.
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::245a1bc885463a3778e22f8e39c620b6
https://doi.org/10.1007/978-1-0716-2914-7_22
https://doi.org/10.1007/978-1-0716-2914-7_22
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2614
Our increased understanding of how a cell's microenvironment influences its behavior has fueled an interest in three-dimensional (3D) cell cultures for drug discovery. Particularly, scaffold-based 3D cultures are expected to recapitulate in vivo tiss
Autor:
Darrin J. Pochan, Nairiti Sinha, Christopher J. Kloxin, Matthew Langenstein, Jeffery G. Saven
Publikováno v:
Chemical Reviews. 121:13915-13935
Peptides have been extensively utilized to construct nanomaterials that display targeted structure through hierarchical assembly. The self-assembly of both rationally designed peptides derived from naturally occurring domains in proteins as well as i
Autor:
Darrin J. Pochan, Jeffery G. Saven, Christopher J. Kloxin, Zvi Kelman, Nairiti Sinha, Grethe V. Jensen
Publikováno v:
Journal of Biotechnology. 330:57-60
Computational design of fully artificial peptides is extensively researched by material scientists and engineers for the construction of novel nanostructures and biomaterials. Such design has yielded a peptide-based building block or bundlemer, a coi
Autor:
Lulu Xue, Ningqiang Gong, Sarah J. Shepherd, Xinhong Xiong, Xueyang Liao, Xuexiang Han, Gan Zhao, Chao Song, Xisha Huang, Hanwen Zhang, Marshall S. Padilla, Jingya Qin, Yi Shi, Mohamad-Gabriel Alameh, Darrin J. Pochan, Karin Wang, Fanxin Long, Drew Weissman, Michael J. Mitchell
Publikováno v:
Journal of the American Chemical Society. 144(22)
The development of lipid nanoparticle (LNP) formulations for targeting the bone microenvironment holds significant potential for nucleic acid therapeutic applications including bone regeneration, cancer, and hematopoietic stem cell therapies. However