Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Darrin A. Lindhout"'
Autor:
Lei Ling, Hui Tian, Alex M. DePaoli, R. Marc Learned, Taruna Arora, Xunshan Ding, Mark Humphrey, Hong Yang, Jer-Yuan Hsu, Kalyani Mondal, Darrin A. Lindhout, Van Phung, Xueyan Wang, Mei Zhou
PDF file - 142KB, Supplementary Table S1. Serum Parameters of db/db Mice After Continuous Exposure to FGF19 or M70 for 24 Weeks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fee3bc699f1740d0952d152d013b5cc
https://doi.org/10.1158/0008-5472.22403538
https://doi.org/10.1158/0008-5472.22403538
Autor:
Yannan Xi, Benbo Song, Iris Ngan, Mark J. Solloway, Mark Humphrey, Yan Wang, Kalyani Mondal, Hao Wu, Wenhui Liu, Darrin A. Lindhout, Diana Li, Hugo Matern, Avantika Kekatpure, Raj Haldankar, Daniel D. Kaplan, Hong Yang, Ophelia Pedersen, Anna Chen, Mei Zhou, Bethany Winans, Wei Guo, Alan Kutach, Marie Fanget, Michael Fox, Jie Tang, Jiping Zha, Husam Younis, David Shen, Alex DePaoli, Hui Tian, Zhonghao Liu
Publikováno v:
Cell Reports. 39:110872
Type 1 diabetes mellitus (T1D) is a chronic disease with potentially severe complications, and β-cell deficiency underlies this disease. Despite active research, no therapy to date has been able to induce β-cell regeneration in humans. Here, we dis
Autor:
Hui Tian, Benbo song, Bethany Winans, Darrin A. Lindhout, Mei Zhou, Wei Guo, Hao Wu, Jiping Zha, Mark J. Solloway, Hugo Matern, Zhonghao Liu, Daniel D. Kaplan, Yan Wang, Michael Fox, Husam Younis, Marie Fanget, Ophelia Pedersen, Diana Li, Alex M. DePaoli, Yannan Xi, David Shen, Anna Chen, Iris Ngan, Hong Yang, Avantika Kekatpure, Wenhui Liu, Alan Kutach, Jie Tang, Raj Haldankar, Mark G. Humphrey, Kalyani Mondal
Publikováno v:
SSRN Electronic Journal.
Type 1 Diabetes (T1D) is a chronic disease with potentially severe complications, and β-cell deficiency underlies this disease. Despite active research, no therapy to date has been able to induce β-cell regeneration in humans. Here, we discovered t
Autor:
Van Phung, Higbee Jared Martin, Marilyn Wang, Rowena Suriben, Yan Wang, Dina A. Ayupova, Diana Li, Hung-I Harry Chen, Subhash D. Katewa, André O. White, Zhengyu Gao, Michele McEntee, Andrea Olland, Damodharan Lakshminarasimhan, Richard Ventura, Michael Chen, Julie Oeffinger, Jie Tang, Shelley R. Starck, Jer-Yuan Hsu, Darrin A. Lindhout, Pranali Taskar, Kalyani Mondal, Mark J. Solloway, Raj Haldankar, Avantika Kekatpure, Bernard B. Allan, Betty Chan Li
Publikováno v:
Nature medicine. 26(8)
Cancer cachexia is a highly prevalent condition associated with poor quality of life and reduced survival1. Tumor-induced perturbations in the endocrine, immune and nervous systems drive anorexia and catabolic changes in adipose tissue and skeletal m
Autor:
Kalyani Mondal, Geoffrey Horner, Manuel E. Lopez, Mark J. Solloway, Chen M, Laird T, Gao Z, Raj Haldankar, Andre White, Yao J, Wang M, Tang J, Avantika Kekatpure, Hugo Matern, Bernard B. Allan, Chan J, Alice Chen Y, Dina A. Ayupova, Higbee Jared Martin, Damodharan Lakshminarasimhan, Li B, Tian H, To C, Hsu Jy, Alan Kutach, Tom Parsons, Wang Sp, Shen Wd, Suzanne Christine Crawley, Joo W, Junming Yie, Darrin A. Lindhout, cEntee M, Fu D
Publikováno v:
Nature. 550:255-259
Under homeostatic conditions, animals use well-defined hypothalamic neural circuits to help maintain stable body weight, by integrating metabolic and hormonal signals from the periphery to balance food consumption and energy expenditure. In stressed
Autor:
Jer-Yuan Hsu, Suzanne Crawley, Michael Chen, Dina A. Ayupova, Darrin A. Lindhout, Jared Higbee, Alan Kutach, William Joo, Zhengyu Gao, Diana Fu, Carmen To, Kalyani Mondal, Betty Li, Avantika Kekatpure, Marilyn Wang, Teresa Laird, Geoffrey Horner, Jackie Chan, Michele McEntee, Manuel Lopez, Damodharan Lakshminarasimhan, Andre White, Sheng-Ping Wang, Jun Yao, Junming Yie, Hugo Matern, Mark Solloway, Raj Haldankar, Thomas Parsons, Jie Tang, Wenyan D. Shen, Yu Alice Chen, Hui Tian, Bernard B. Allan
Publikováno v:
Nature. 551(7680)
This corrects the article DOI: 10.1038/nature24042.
Autor:
Mei Zhou, Mark Humphrey, Van Phung, Xunshan Ding, Kalyani Mondal, R. Marc Learned, Xueyan Wang, Alex M. DePaoli, Taruna Arora, Jer-Yuan Hsu, Hui Tian, Lei Ling, Darrin A. Lindhout, Hong Yang
Publikováno v:
Cancer Research. 74:3306-3316
Hepatocellular carcinoma (HCC), one of the leading causes of cancer-related death, develops from premalignant lesions in chronically damaged livers. Although it is well established that FGF19 acts through the receptor complex FGFR4-β-Klotho (KLB) to
Autor:
Elisabetta Viani Puglisi, R. Andrew Marshall, Darrin A. Lindhout, Sean A. McKenna, Insil Kim, Colin Echeverría Aitken, Joseph D. Puglisi
Publikováno v:
Nature Protocols. 2:3270-3277
RNA synthesis using in vitro transcription by phage T7 RNA polymerase allows preparation of milligram quantities of RNA for biochemical, biophysical and structural investigations. Previous purification approaches relied on gel electrophoretic or grav
Autor:
Corey W. Liu, Joseph D. Puglisi, Sean A. McKenna, Colin Echeverría Aitken, Darrin A. Lindhout
Publikováno v:
Progress in Nuclear Magnetic Resonance Spectroscopy. 51:199-215
The Role of Electrostatics in the Interaction of the Inhibitory Region of Troponin I with Troponin C
Publikováno v:
Biochemistry. 44:14750-14759
We have addressed the electrostatic interactions occurring between the inhibitory region of cardiac troponin I with the C-lobe of troponin C using scanning glycine mutagenesis of the inhibitory region. We report variations in the electric potentials