Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Darrick T. Balu"'
Autor:
Stephanie E. Brown, Ziyi (Zephyr) Wang, Emily L. Newman, Elif Engin, Sabina Berretta, Darrick T. Balu, Oluwarotimi O. Folorunso
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundNeurodevelopmental disorders (NDDs) can cause debilitating impairments in social cognition and aberrant functional connectivity in large-scale brain networks, leading to social isolation and diminished everyday functioning. To facilitate th
Externí odkaz:
https://doaj.org/article/14d7dc0db10340a084396a2763a6e052
Autor:
Oluwarotimi O. Folorunso, Stephanie E. Brown, Jugajyoti Baruah, Theresa L. Harvey, Shekib A. Jami, Inna Radzishevsky, Herman Wolosker, James M. McNally, John A. Gray, Anju Vasudevan, Darrick T. Balu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The proper development and function of telencephalic GABAergic interneurons is critical for maintaining the excitation and inhibition (E/I) balance in cortical circuits. Glutamate contributes to cortical interneuron (CIN) development via N-m
Externí odkaz:
https://doaj.org/article/c1a3de421db14b62abea4c8f005bf011
Autor:
David D. Aguilar, Leana K. Radzik, Felipe L. Schiffino, Oluwarotimi O. Folorunso, Mark R. Zielinski, Joseph T. Coyle, Darrick T. Balu, James M. McNally
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Abnormalities in electroencephalographic (EEG) biomarkers occur in patients with schizophrenia and those clinically at high risk for transition to psychosis and are associated with cognitive impairment. Converging evidence suggests N-methyl-
Externí odkaz:
https://doaj.org/article/f8ea1784276d4c4a8fbcc40d7b2e1e8c
Autor:
Darrick T. Balu, Harry Pantazopoulos, Cathy C.Y. Huang, Kevin Muszynski, Theresa Lynn Harvey, Yota Uno, Jacki M. Rorabaugh, Claire R. Galloway, Christian Botz-Zapp, Sabina Berretta, David Weinshenker, Joseph T. Coyle
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104511- (2019)
Although β-amyloid plaques are a well-recognized hallmark of Alzheimer's disease (AD) neuropathology, no drugs reducing amyloid burden have shown efficacy in clinical trials, suggesting that once AD symptoms emerge, disease progression becomes indep
Externí odkaz:
https://doaj.org/article/1a5c97093b8940d89bd516ac40a6131c
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 2, Pp 671-682 (2012)
There is substantial evidence, both pharmacological and genetic, that hypofunction of the N-methyl-d-aspartate receptor (NMDAR) is a core pathophysiological feature of schizophrenia. There are morphological brain changes associated with schizophrenia
Externí odkaz:
https://doaj.org/article/e1bcff4fa1a145e886f3b45463c163b5
Autor:
Stephen A. Tapanes, Dena Arizanovska, Madelen M. Díaz, Oluwarotimi O. Folorunso, Theresa Harvey, Stephanie E. Brown, Inna Radzishevsky, Liesl N. Close, Jonathan R. Jagid, Joacir Graciolli Cordeiro, Herman Wolosker, Darrick T. Balu, Daniel J. Liebl
Publikováno v:
Glia. 70:1133-1152
Synaptic damage is one of the most prevalent pathophysiological responses to traumatic CNS injury and underlies much of the associated cognitive dysfunction; however, it is poorly understood. The D-amino acid, D-serine, serves as the primary co-agoni
Autor:
Oluwarotimi O. Folorunso, Theresa L. Harvey, Stephanie E. Brown, Gabriele Chelini, Sabina Berretta, Darrick T. Balu
Publikováno v:
Neuroscience letters. 792
Alzheimer's disease (AD) is characterized behaviorally by cognitive deterioration and emotional disruption, and neuropathologically by amyloid-β (A β) plaques, neurofibrillary tangles, and complement C3 (C3)-expressing neurotoxic, reactive astrocyt
Publikováno v:
Am J Psychiatry
Publikováno v:
Neurochem Res
Shape-shifting, a phenomenon wide-spread in folklore, refers to the ability to physically change from one identity to another, typically from an innocuous entity to a destructive one. The amino acid D-serine over the last 25 years has "shape-shifted"
Autor:
Oluwarotimi Folorunso, David Aguilar, James M. McNally, Darrick T. Balu, Leana K. Radzik, Mark R. Zielinski, Joseph T. Coyle, Felipe L. Schiffino
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
IntroductionAbnormalities in electroencephalographic (EEG) biomarkers occur in patients with schizophrenia and those clinically at high risk for transition to psychosis and are associated with cognitive impairment. While the pathophysiology of schizo