Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Darrick Pope"'
Publikováno v:
Journal of Chemical Information and Modeling. 54:1157-1165
The zinc metalloprotease neprilysin (NEP) promiscuously degrades small bioactive peptides. NEP is among a select group of metalloenzymes that degrade the amyloid beta-peptide (Aβ) in vivo and in situ. Since accumulation of neurotoxic Aβ aggregates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3be4216b8f0331892d9b28c55dcac9f
https://doi.org/10.1021/ci500015m
https://doi.org/10.1021/ci500015m
Autor:
A. Michael Crider, Abdu Adem, Adel M. Abuzenadah, Ali Jawad, Benjamin P. Repsold, Boris Decourt, Carmen Martínez-Rincón, Daniel Jun, Darrick Pope, David F. Fischer, David William Klaver, Dolores Rodríguez-Martínez, Eric A. Owens, Eugenie Nepovimova, Faizul H. Nasim, Fares Zeidán-Chuliá, Farhan Jalees Ahmad, Farzana L. Ansari, Filip Zemek, Giuseppina Tesco, Gjumrakch Aliev, Iqbal Ahmad, Ismael Ortuño-Soriano, Jacobus P. Petzer, Jacques Joubert, Jan Korabecny, Javed Ahmad, José Cláudio Fonseca Moreira, José L. Pacheco-del-Cerro, Julie Frearson, Kamil Kuca, Kamil Musilek, Karin E. Sandoval, Katarina Spilovska, Kenneth A. Witt, Lara Pacheco-Cuevas, Louis H.A. Prins, Maged M. Henary, Maria Kontoyianni, Marwan Sabbagh, Mauricio Alcolea-Palafox, Michael Cascio, Michael D. Wall, MiMi Macias, Mohamed A. Embaby, Mohammad A. Kamal, Mohammad Zaki Ahmad, Nasimudeen R. Jabir, Nigel H. Grieg, Nighat Sultana, Omar Aziz, Ondrej Soukup, Othman Sulaiman, Paloma Posada-Moreno, Pierfausto Seneci, Raza Murad Ghalib, Rokiah Hashim, Roland W. Bürli, Sarel F. Malan, Sayed Hasan Mehdi, Shams Tabrez, Sohail Akhter, Surendra Reddy Punganuru, Tyler L. Dost, Umer Rashid, Vageesh Revadigar, Vikneswaran Murugaiyah, Zafar Saied Saify, Ziyaur Rahman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cb3e4ebcf1e869a366b4b8ce214dec4
https://doi.org/10.1016/b978-0-12-803959-5.50020-9
https://doi.org/10.1016/b978-0-12-803959-5.50020-9
Autor:
Darrick Pope, Michael Cascio
Neprilysin (NEP) is one of the enzymes in the zinc-metalloendopeptidase family that displays a broad specificity in degrading small bioactive peptides. Crystal structures of seven NEP-inhibitor complexes as well as biochemical characterization of NEP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea7258fa7321e9ac75ceee50f367c13b
https://doi.org/10.1016/b978-0-12-803959-5.50013-1
https://doi.org/10.1016/b978-0-12-803959-5.50013-1