Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Darren Yong"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract E3 ubiquitin ligases are critical to the protein degradation pathway by catalyzing the final step in protein ubiquitination by mediating ubiquitin transfer from E2 enzymes to target proteins. Nedd4 is a HECT domain-containing E3 ubiquitin li
Externí odkaz:
https://doaj.org/article/6394859c60a04ec9a06bd35c4b9cd171
Autor:
Eitan Kugler, Shreyas Madiwale, Darren Yong, Julie A. I. Thoms, Yehudit Birger, David B. Sykes, Johannes Schmoellerl, Aneta Drakul, Valdemar Priebe, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei Chen, Brian Raught, Qiao Liu, Heather Ogana, Elisabeth Liedke, Jean-Pierre Bourquin, Johannes Zuber, Michael Milyavsky, John Pimanda, Gilbert G. Privé, Shai Izraeli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The ERG (ETS-related gene) transcription factor is linked to various types of cancer, including leukemia. However, the specific ERG domains and co-factors contributing to leukemogenesis are poorly understood. Drug targeting a transcription f
Externí odkaz:
https://doaj.org/article/d7035b0bdc8b4304be06aaa591c4d83a
Autor:
Duc Minh Nguyen, Rath, Deanna H., Devost, Dominic, Pétrin, Darlaine, Rizk, Robert, Ji, Alan X., Narayanan, Naveen, Darren Yong, Yong, Darren, Kuntz, Douglas A., Mian, Maha U. Q., Pomroy, Neil C., Keszei, Alexander F. A., Benlekbir, Samir, Mazhab-Jafari, Mohammad T., Rubinstein, John L., Hébert, Terence E., Privé, Gilbert G.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/23/2024, Vol. 121 Issue 17, p1-10, 10p
Autor:
Eitan Kugler, Shreyas Madiwale, Darren Yong, Yehudit Birger, Julie AI Thoms, David B Sykes, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei Chen, Brian Raught, Qiao Liu, Michael Milyavsky, John Pimanda, Gilbert G Privé, Shai Izraeli
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S215-S216
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::170fa8777d05455dc8dca76b47a7bed9
https://doi.org/10.1016/s2152-2650(22)01225-3
https://doi.org/10.1016/s2152-2650(22)01225-3
Autor:
Eitan Kugler, Shreyas Madiwale, Darren Yong, Yehudit Birger, Julie Thoms, David Sykes, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei Chen, Brian Raught, Qiao Liu, Michael Milyavsky, John Pimanda, Gilbert Privé, Shai Izraeli
The ETS transcription factor ERG is involved in several cancers including leukemias. We and others have demonstrated a direct role for ERG in leukemia initiation and maintenance of several subtypes of myeloid and lymphoid leukemias. However, ERG doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0246fccc765f49a40b4c85c49c541e
https://doi.org/10.21203/rs.3.rs-1426447/v1
https://doi.org/10.21203/rs.3.rs-1426447/v1
Autor:
Eitan Kugler, Shreyas Madiwale, Darren Yong, Yehudit Birger, Julie AI Thoms, David B Sykes, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei Chen, Brian Raught, Qiao Liu, Michael Milyavsky, John Pimanda, Gilbert G Privé, Shai Izraeli
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124c1a3cb4aa491c0d8e4ce02b053c36
https://doi.org/10.1016/s2152-2650(22)00769-8
https://doi.org/10.1016/s2152-2650(22)00769-8
Autor:
Anthony G. Fane, Stanislaus Raditya Suwarno, Emile Cornelissen, Lee Nuang Sim, Darren Yong Shern Lee, Tzyy Haur Chong
Publikováno v:
Chemosphere. 220:107-115
The presence of transparent exopolymer particles (TEP) in water bodies has been related to several adverse impacts in various water treatment processes. In recent years, there have been an increasing number of publications relating to TEP. Unfortunat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1bcac37400f1f2ff1e52b2dcdadc9f
https://doi.org/10.1016/j.chemosphere.2018.12.066
https://doi.org/10.1016/j.chemosphere.2018.12.066
Autor:
Gilbert Privé, Duc Minh Nguyen, Alan Ji, Darren Yong, Andrew Zhai, Neil Pomroy, Douglas Kuntz, Darlaine Petrain, Dominic Devost, Terry Hebert
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 78:a162-a162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a96ba76307bd4bd22ef3411a5cb57b
https://doi.org/10.1107/s2053273322098370
https://doi.org/10.1107/s2053273322098370
Autor:
Yehudit Birger, Julie A. I. Thoms, Gilbert G. Privé, Eitan Kugler, John E. Pimanda, Shreyas Madiwale, Shai Izraeli, Avigail Rein, Darren Yong
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:S180-S181
The ETS transcription factor ERG has a crucial role in hematopoiesis. It is essential for hematopoietic stem cell maintenance and megakaryopoiesis. Increased expression of ERG is associated with poor prognosis in acute myeloid leukemia. Previous stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2699993cbba57e6cba9c38e9dc4c2ff0
https://doi.org/10.1016/s2152-2650(20)30713-8
https://doi.org/10.1016/s2152-2650(20)30713-8
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