Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Darren Wethington"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009931 (2022)
Cytometry experiments yield high-dimensional point cloud data that is difficult to interpret manually. Boolean gating techniques coupled with comparisons of relative abundances of cellular subsets is the current standard for cytometry data analysis.
Externí odkaz:
https://doaj.org/article/a8882e979b7d4715acc9a9a6eec8a863
Autor:
Syed Abbas Ali, Yuya Nagai, Dean A. Lee, Gabriel Ghiaur, Marcelo de Souza Fernandes Pereira, Ezgi Elmas, Philip H. Imus, Meisam Naeimi Kararoudi, Darren Wethington, Ivan Borrello
Publikováno v:
Blood
Multiple myeloma (MM) is a plasma cell neoplasm that commonly expresses CD38. Daratumumab (DARA), a human monoclonal antibody targeting CD38, has significantly improved the outcome of patients with relapsed or refractory MM, but the response is trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71813a66573bec6f1fa365235f8a45e9
https://doi.org/10.1182/blood.2020006200
https://doi.org/10.1182/blood.2020006200
Mass cytometry (CyTOF) gives unprecedented opportunity to simultaneously measure up to 40 proteins in single cells, with a theoretical potential to reach 100 proteins. This high-dimensional single-cell information can be very useful to dissecting mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54624a7f59c578144d911bfc1f0b1b13
https://doi.org/10.1101/2021.12.02.470955
https://doi.org/10.1101/2021.12.02.470955
Publikováno v:
bioRxiv
Cytometry experiments yield high-dimensional point cloud data that is difficult to interpret manually. Boolean gating techniques coupled with comparisons of relative abundances of cellular subsets is the current standard for cytometry data analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecf72f5732e51d2cefee848cc3c31f9
https://europepmc.org/articles/PMC8095200/
https://europepmc.org/articles/PMC8095200/
Autor:
Andrew Stiff, Robert Wesolowski, William E. Carson, Himanshu Savardekar, Megan C. Duggan, Logan Good, Darren Wethington, Luke Scarberry, Brooke Benner, Steven Sun, Jack Hedberg, Gabby Lapurga
Publikováno v:
Cancer Research. 80:3414-3414
Myeloid derived suppressor cells (MDSCs) antagonize antitumor immune responses, and limit the efficacy of immune based therapies for cancer. As a result, MDSCs have garnered attention as therapeutic targets. Unfortunately, there has been limited succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dacade39868697b62c9deb0d041f491
https://doi.org/10.1158/1538-7445.am2020-3414
https://doi.org/10.1158/1538-7445.am2020-3414
Autor:
William C. L. Stewart, Mark E. Peeples, Jayajit Das, Phylip Chen, Alan S. Perelson, Susan D. Reynolds, Olivia Harder, Karthik Uppulury, Darren Wethington, Tiffany King, Stefan Niewiesk
Publikováno v:
J R Soc Interface
Respiratory syncytial virus (RSV) is a common virus that can have varying effects ranging from mild cold-like symptoms to mortality depending on the age and immune status of the individual. We combined mathematical modelling using ordinary differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b925df69f6bdd099d1e678eeca666847
https://doi.org/10.1098/rsif.2019.0389
https://doi.org/10.1098/rsif.2019.0389
Autor:
Wethington, Darren1,2 darren.wethington@nationwidechildrens.org, Mukherjee, Sayak3, Das, Jayajit1,2,4,5,6,7 jayajit@gmail.com
Publikováno v:
Quantitative Biology. Mar2023, Vol. 11 Issue 1, p59-71. 13p.
Autor:
Grewal, Rajdeep Kaur1 (AUTHOR), Das, Jayajit1,2,3,4,5,6 (AUTHOR) jayajit@gmail.com
Publikováno v:
PLoS Computational Biology. 5/18/2022, Vol. 18 Issue 5, p1-33. 33p. 3 Charts, 7 Graphs.
Autor:
Mukherjee, Soham1 (AUTHOR), Wethington, Darren2,3 (AUTHOR), Dey, Tamal K.1 (AUTHOR), Das, Jayajit2,3,4,5 (AUTHOR) jayajit@gmail.com
Publikováno v:
PLoS Computational Biology. 3/21/2022, Vol. 18 Issue 3, p1-22. 22p. 2 Diagrams, 6 Graphs.