Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Darren Wan‐Teck Lim"'
Publikováno v:
Journal of Big Data, Vol 11, Iss 1, Pp 1-28 (2024)
Abstract Hepatocellular carcinoma (HCC) presents a major health issue worldwide. This study introduces the HepScope gene set, developed through a hybrid approach that utilizes single-cell RNA sequencing (scRNA-seq), spatial transcriptomics (stRNA-seq
Externí odkaz:
https://doaj.org/article/49d4a783d21542e4a48efc9d79727e60
Autor:
Ariantika Ariantika, Rahayu Lubis, Asfriyati Asfriyati, Taufik Ashar, Nurmaini Nurmaini, Noni Novisari Soeroso, Kamal Basri Siregar, Darren Wan-Teck Lim
Publikováno v:
Jurnal Respirasi, Vol 10, Iss 3, Pp 228-235 (2024)
Introduction: Quality of life (QoL) is a multidomain concept that assesses a person through health status, functional status, and symptoms. The patient's QoL is greatly reduced due to the course of disease, severity of symptoms, and side effects of c
Externí odkaz:
https://doaj.org/article/8f66a92efbff4e15929efc126e9227e9
Autor:
Yuan Chen, Li Zhang, Xingjie Wu, Xuecheng Sun, Noah R. Sundah, Chi Yan Wong, Auginia Natalia, John K. C. Tam, Darren Wan-Teck Lim, Balram Chowbay, Beng Ti Ang, Carol Tang, Tze Ping Loh, Huilin Shao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Conventional magnetic biosensing technologies have reduced analytical capacity for magnetic field dimensionality and require extensive sample processing. To address these challenges, we spatially engineer 3D magnetic response gradients for d
Externí odkaz:
https://doaj.org/article/1205fa90508243ea8bd82a8fd32f8525
Autor:
Chaliza Soliha, Noni Novisari Soeroso, Fannie Rizki Ananda, Rozaimah Zain-Hamid, Syamsul Bihar, Darren Wan-Teck Lim
Publikováno v:
Jurnal Respirasi, Vol 10, Iss 2, Pp 93-98 (2024)
Introduction: One of the main ingredients in cigarettes is nicotine, which has a significant impact on a person's dependence on cigarettes. Nicotine can be detected in a smoker's urine as a sign that his body is processing nicotine. The important enz
Externí odkaz:
https://doaj.org/article/6f2fcfb93ac14d968b6b71b2938af08a
Autor:
Janice Ser Huey Tan, Timothy Kwang Yong Tay, Enya Hui Wen Ong, Michael Fehlings, Daniel Shao-Weng Tan, Nadiah Binte Sukma, Eileen Xueqin Chen, Jen-Hwei Sng, Connie Siew Poh Yip, Kok Hing Lim, Darren Wan-Teck Lim, Narayanan Gopalakrishna Iyer, Jacqueline Siok Gek Hwang, Melvin Lee Kiang Chua, Mei-Kim Ang
Publikováno v:
European Thyroid Journal, Vol 13, Iss 1, Pp 1-10 (2024)
Objective: Anaplastic thyroid cancer (ATC) is an aggressive disease associated with poor outcomes and resistance to therapies. Our study aim was to evaluate the activity of a combinatorial regimen of sandwich sequencing of pembrolizumab immunotherapy
Externí odkaz:
https://doaj.org/article/bcbd473df09d426dac1f9589976fe55d
Autor:
Ning-Yuan Lee, Melissa Hum, Sabna Zihara, Lanying Wang, Matthew K. Myint, Darren Wan-Teck Lim, Chee-Keong Toh, Anders Skanderup, Jens Samol, Min-Han Tan, Peter Ang, Soo-Chin Lee, Eng-Huat Tan, Gillianne G. Y. Lai, Daniel S. W. Tan, Yoon-Sim Yap, Ann S. G. Lee
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-15 (2023)
Abstract Background Cancer predisposition is most often studied in the context of single cancers. However, inherited cancer predispositions can also give rise to multiple primary cancers. Yet, there is a paucity of studies on genetic predisposition i
Externí odkaz:
https://doaj.org/article/606c22b537b34d029e0606d233c3a1b7
Autor:
Darren Wan-Teck Lim, Hsiang-Fong Kao, Lisda Suteja, Constance H. Li, Hong Sheng Quah, Daniel Shao-Weng Tan, Sze-Huey Tan, Eng-Huat Tan, Wan-Ling Tan, Justina Nadia Lee, Felicia Yu-Ting Wee, Amit Jain, Boon-Cher Goh, Melvin L. K. Chua, Bin-Chi Liao, Quan Sing Ng, Ruey-Long Hong, Mei-Kim Ang, Joe Poh-Sheng Yeong, N. Gopalakrishna Iyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Single-agent checkpoint inhibitor (CPI) activity in Epstein-Barr Virus (EBV) related nasopharyngeal carcinoma (NPC) is limited. Dual CPI shows increased activity in solid cancers. In this single-arm phase II trial (NCT03097939), 40 patients
Externí odkaz:
https://doaj.org/article/9dac3f0d6a524296a18f65ed171dcbf2
Autor:
Ning-Yuan Lee, Melissa Hum, Sabna Zihara, Lanying Wang, Matthew K. Myint, Darren Wan-Teck Lim, Chee-Keong Toh, Anders Skanderup, Jens Samol, Min-Han Tan, Peter Ang, Soo-Chin Lee, Eng-Huat Tan, Gillianne G. Y. Lai, Daniel S. W. Tan, Yoon-Sim Yap, Ann S. G. Lee
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/e9e788a2a8014f09833d11de0c9d51dd
Autor:
Muhammad Harbi Praditya, Noni Novisari Soeroso, Setia Putra Tarigan, Taufik Ashar, Darren Wan-Teck Lim
Publikováno v:
Jurnal Respirasi, Vol 9, Iss 1, Pp 12-17 (2023)
Introduction: Patients with lung adenocarcinoma following epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment will develop acquired resistance after 7 to 16 months of starting the medication, indicated by the emergence of
Externí odkaz:
https://doaj.org/article/a0d5e485a847407f8a298ce92278cc4f
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 6, Pp 100512- (2023)
Both tissue and plasma-based next generation sequencing (NGS) facilitate the identification of actionable oncogene alterations at diagnosis and resistant mechanisms on progression. The value of longitudinal profiling is less established among patient
Externí odkaz:
https://doaj.org/article/9131cf6902704589975b0d63fb756176