Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Darren W. T. Lim"'
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S6. Adverse events of special interest (patients treated with spartalizumab)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f0d6f1f0449b030b61c2ad5339b24d
https://doi.org/10.1158/1078-0432.22484067
https://doi.org/10.1158/1078-0432.22484067
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S7. Primary PK parameters for spartalizumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4654f298b3b5b95f2d1fe549d47835ec
https://doi.org/10.1158/1078-0432.22484064
https://doi.org/10.1158/1078-0432.22484064
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Figure S2. Adverse events in crossover group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28793f51c06cf4dd88863fe91eeb4c0b
https://doi.org/10.1158/1078-0432.22484097.v1
https://doi.org/10.1158/1078-0432.22484097.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S2. Chemotherapy regimens given to patients in the chemotherapy arm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e697e4b2a33e6eb31107d28fe03682
https://doi.org/10.1158/1078-0432.22484082.v1
https://doi.org/10.1158/1078-0432.22484082.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S5. Adverse events ({greater than or equal to} 15% incidence of all grades events in any of the patient treatment arms)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db369c8bd894b191faa792dd64a2b3a
https://doi.org/10.1158/1078-0432.22484070.v1
https://doi.org/10.1158/1078-0432.22484070.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Purpose:No standard treatment exists for platinum-refractory, recurrent/metastatic nasopharyngeal cancer (NPC). This phase II study (NCT02605967) evaluated progression-free survival (PFS) of spartalizumab, an antiprogrammed cell death protein-1 (PD-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16654b198e7fddf4a1e74eebe9adc8c2
https://doi.org/10.1158/1078-0432.c.6531318
https://doi.org/10.1158/1078-0432.c.6531318
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Figure S3. Best percentage change from baseline in sum of diameters of target lesions for patients treated with spartalizumab (A) and chemotherapy (B)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e129ac1ba81c71214802a67ed0d560d
https://doi.org/10.1158/1078-0432.22484088
https://doi.org/10.1158/1078-0432.22484088
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S1. Patient disposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d05607a694aad5f719edf7b9f542a4b
https://doi.org/10.1158/1078-0432.22484085.v1
https://doi.org/10.1158/1078-0432.22484085.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Figure S1. CONSORT diagram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3241828f2bbcae8bf4e25873af7fa979
https://doi.org/10.1158/1078-0432.22484100
https://doi.org/10.1158/1078-0432.22484100
Autor:
Hong Sheng Quah, Rachael Bashford-Rogers, Daniel S.W. Tan, Melvin L.K. Chua, Darren W. T. Lim, Annalisa Mupo, Lisda Suteja, Yvonne Hui-Fang Teng, George S. Vassiliou, N. Gopalakrishna Iyer, João Lopes Dias
Publikováno v:
Cancer Immunology, Immunotherapy
Despite the conventional view that a truly random V(D)J recombination process should generate a highly diverse immune repertoire, emerging reports suggest that there is a certain bias toward the generation of shared/public immune receptor chains. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0d072485861dd6bd6c635d7cd3824d